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Compassionate use of the Seraph® 100 affinity blood filter in pediatric refractory streptococcal septic shock: a case report. [PDF]
Front PediatrMontero-Yeboles R +5 more
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Lancet, The, 1998
1. Septic shock is still a major complication of patients in intensive care units (ICUs) and, therefore, a main goal of ICU-related research. 2. After the unsatisfying results of multicenter clinical trials in blocking proinflammatory mediators such as tumor necrosis factor and interleukin-1 or endotoxin itself, research has focused on other important ...
Mark E Astiz, Eric C Rackow, M E Astiz
exaly +5 more sources
1. Septic shock is still a major complication of patients in intensive care units (ICUs) and, therefore, a main goal of ICU-related research. 2. After the unsatisfying results of multicenter clinical trials in blocking proinflammatory mediators such as tumor necrosis factor and interleukin-1 or endotoxin itself, research has focused on other important ...
Mark E Astiz, Eric C Rackow, M E Astiz
exaly +5 more sources
The Lancet, 2005
Septic shock, the most severe complication of sepsis, is a deadly disease. In recent years, exciting advances have been made in the understanding of its pathophysiology and treatment. Pathogens, via their microbial-associated molecular patterns, trigger sequential intracellular events in immune cells, epithelium, endothelium, and the neuroendocrine ...
Djillali, Annane +2 more
openaire +2 more sources
Septic shock, the most severe complication of sepsis, is a deadly disease. In recent years, exciting advances have been made in the understanding of its pathophysiology and treatment. Pathogens, via their microbial-associated molecular patterns, trigger sequential intracellular events in immune cells, epithelium, endothelium, and the neuroendocrine ...
Djillali, Annane +2 more
openaire +2 more sources
Shock, 2022
ABSTRACT Sepsis and septic shock usually show a high mortality rate and frequently need of intensive care unit admissions. After fluid resuscitation, norepinephrine (NE) is the first-choice vasopressor in septic shock patients. However, high-NE doses are associated with increased rates of adverse effects and mortality.
Elio, Antonucci +4 more
openaire +2 more sources
ABSTRACT Sepsis and septic shock usually show a high mortality rate and frequently need of intensive care unit admissions. After fluid resuscitation, norepinephrine (NE) is the first-choice vasopressor in septic shock patients. However, high-NE doses are associated with increased rates of adverse effects and mortality.
Elio, Antonucci +4 more
openaire +2 more sources
SEPTIC ABORTION AND SEPTIC SHOCK
Clinical Obstetrics and Gynecology, 1970PIP: Septic shock in obstetric cases is described, and patient management is discussed. Cases of septic abortion complicated by septic shock differ from those resulting from bacterial shock. During the 10 years prior to 1968, Boston City Hospital had a yearly average of 550-600 abortions, and about 26% were septic.
B A, Santamarina, S A, Smith
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Septic Shock (Endotoxic Shock)
Clinical Obstetrics and Gynecology, 1973PIP: The pathophysiology, clinical aspects, medical, and surgical management of endotoxin shock are reviewed. In the primate, the pathophysiology of endotoxin shock is contributed to by selective vasopasm, disseminated intravascular coagulation, and reduced myocardial response to sympathetic stimuli. Studies in the baboon measured various parameters of
D, Cavanagh, P S, Rao
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Pathophysiology of Septic Shock
Critical Care Clinics, 2018Fundamental features of septic shock are vasodilation, increased permeability, hypovolemia, and ventricular dysfunction. Vasodilation owing to increased nitric oxide and prostaglandins is treated with vasopressors (norepinephrine first). Increased permeability relates to several pathways (Slit/Robo4, vascular endothelial growth factor, angiopoietin 1 ...
James A, Russell +2 more
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