Results 71 to 80 of about 148,592 (309)

Diagnostic and Prognostic Significance of the Prothrombin Time/International Normalized Ratio in Sepsis and Septic Shock

Clinical and Applied Thrombosis/Hemostasis, 2022
Objective The study investigates the diagnostic and prognostic significance of the prothrombin time/international normalized ratio (PT/INR) in patients with sepsis and septic shock.
Tobias Schupp MD, Kathrin Weidner MD, Jonas Rusnak MD, Schanas Jawhar MS, Jan Forner MS, Floriana Dulatahu MS, Lea Marie Brück MS, Ursula Hoffmann MD, Thomas Bertsch MD, Julian Müller MD, Christel Weiß PhD, Ibrahim Akin MD, Michael Behnes MD   +12 more
doaj   +1 more source

Immune Checkpoint Inhibitor–Related Myositis and Associated Triad Overlap Syndrome

Arthritis Care &Research, EarlyView.
Objective Immune checkpoint inhibitor (ICI) myositis is a rare but a highly morbid condition, particularly with the ICI myositis triad syndrome of myositis, myocarditis, and myasthenia gravis. We report the clinical characteristics of ICI myositis and all‐cause mortality in these patients.
Selene Rubino, Grant W. Cannon, Brian C. Sauer, Jorge Rojas, Gregory J. Stoddard, Gary A. Kunkel, Jessica A. Walsh, Bryant R. England, Joshua F. Baker, Tawnie J. Braaten   +9 more
wiley   +1 more source

Translational gap in pediatric septic shock management: an ESPNIC perspective [PDF]

, 2019
International audienceBACKGROUND: The Surviving Sepsis Campaign and the American College of Critical Care Medicine guidelines have provided recommendations for the management of pediatric septic shock patients.
Tissieres, Pierre, Javouhey, Etienne, Maclaren, G, Infection, Systemic Inflammation, The, Kneyber, Martin; id_orcid, Nadel, Simon, Kneyber, Martin, Javouhey, E, ESPNIC Refractory Septic Shock Definition taskforce and the Infe, Kneyber, M, Section, Sepsis Espnic, Morin, L, Schlapbach, LJ, Schlapbach, Luregn Jan, Taskforce, Espnic Refractory Septic Shock Definition, Jansen, NJG, Morin, Luc, Infection, Systemic Inflammation,, Peters, MJ, Nadel, S, Maclaren, Graeme, Tissieres, P, Peters, Mark J., Jansen, Nicolaas J. G.   +23 more
core   +1 more source

Decellularized Extracellular Matrix (dECM) in Tendon Regeneration: A Comprehensive Review

Advanced Healthcare Materials, EarlyView.
Decellularized Extracellular Matrix (dECM) offers a promising solution by replicating the native tendon microenvironment and promoting regeneration. This review highlights advances in the decellularization methods, as well as their integration with emerging technologies and translational progress in tendon tissue engineering.
Kumaresan Sakthiabirami, Yeonwoo Park, Seong Kyeong Jo, Min Hee Kim, Jae Hwang Song   +4 more
wiley   +1 more source

Natural Biomaterials for Osteochondral Repair: From Source to Strategy

Advanced Healthcare Materials, EarlyView.
Biological origin‐guided overview of natural biomaterials and therapeutic strategies for osteochondral tissue engineering. The circular diagram categorizes representative materials and strategies into plant/algae‐derived, microbial‐derived, animal‐derived, and human‐derived sources, centered on an osteochondral defect repair model.
Hengyu Liu, Hanyang Zhang, Wenbo Yang, Hao Chen, Jincheng Wang, Fei Chang   +5 more
wiley   +1 more source

Papel do sistema simpático na disfunção cardiovascular do choque séptico [PDF]

, 2014
Dissertação (mestrado) - Universidade Federal de Santa Catarina, Centro de Ciências Biológicas, Programa de Pós-Graduação em Farmacologia, Florianópolis, 2014.O choque séptico é um potente estímulo para a ativação de vários sistemas orgânicos e dentre ...
Favero, Ana Maria
core  

The Systemic Alterations of Lipids, Alanine-Glucose Cycle and Inter-Organ Amino Acid Metabolism in Swine Model Confirms the Role of Liver in Early Phase of Septic Shock

Frontiers in Physiology, 2019
Septic shock is a medical emergency and is one of the main causes of mortality in critically ill patients. Given the pathophysiological complexity of sepsis spectrum and progression in clinical settings, animal models become essential tools to improve ...
Manuela Ferrario, Laura Brunelli, Fuhong Su, Antoine Herpain, Antoine Herpain, Roberta Pastorelli   +5 more
doaj   +1 more source

Double‐Transition‐Metal MXenes: Multimetallic 2D Platforms for Next‐Generation Biomedicine

Advanced Materials, EarlyView.
The present work explores recent progress in double‐transition‐metal MXenes and focuses on their potential as multifunctional biomedical nanoplatforms whose tunable optical, electronic, mechanical, and surface properties enable imaging, theranostics, antimicrobial activity, biosensing, tissue engineering, and drug delivery.
Parsa Namakiaraghi, Mohammad Mozafari, Masoud Soroush   +2 more
wiley   +1 more source

Septic shock resuscitation: what goals and how to achieve them? [PDF]

, 2009
The need to achieve adequate tissue oxygen delivery early in patients with septic shock is well established. However, it is less well recognized that tissue hypoperfusion can exist despite normalization of systemic hemodynamics.
Jakob, Stephan
core   +1 more source

Should Vasopressors Be Started Early in Septic Shock?

, 2021
Sepsis can influence blood volume, its distribution, vascular tone, and cardiac function. Persistent hypotension or the need for vasopressors after volume resuscitation is part of the definition of septic shock. Since increased positive fluid balance has
Jakob, Stephan M., Takala, Jukka, Cioccari, Luca   +2 more
core   +1 more source