Results 51 to 60 of about 2,480,958 (301)

Rapid screening of staphylokinase protein variants using an unpurified cell‐free expression system

open access: yesFEBS Open Bio, EarlyView.
An unpurified cell‐free protein synthesis (CFPS) platform enables rapid functional screening of staphylokinase variants. Direct plasminogen‐activation assays performed in microplate format provide real‐time activity readouts, allowing rapid identification and ranking of variants with improved or reduced fibrinolytic activity without protein ...
Maria Tomková   +3 more
wiley   +1 more source

An enhanced instantaneous detonation model for underwater explosions involving condensed explosives

open access: yesScientific Reports
The dynamic characteristics of underwater explosion phenomena, involving complex multi-phase and multi-interface motions such as shock wave propagation, charge detonation, and bubble motion, are typically predicted using compressible multiphase flow ...
Ji-ping Chen   +5 more
doaj   +1 more source

Long‐term hippocampal alterations and cognitive impairment in a murine model of surgical sepsis

open access: yesFEBS Open Bio, EarlyView.
Using a mouse model of surgical sepsis, we tested long‐term memory and analyzed the transcriptome of single cells isolated from the hippocampus. Survivor mice showed worse memory, loss of certain brain cell subpopulations, and abnormal immune cell activity—suggesting that post‐sepsis brain alterations may be linked to cognitive deficits.
Dong Seong Cho   +4 more
wiley   +1 more source

Reverse undercompressive shock structures in driven thin film flow

open access: yes, 2002
We show experimental evidence of a new structure involving an undercompressive and reverse undercompressive shock for draining films driven by a surface tension gradient against gravity.
A. L. Bertozzi   +10 more
core   +1 more source

On Dispersive and Classical Shock Waves in Bose-Einstein Condensates and Gas Dynamics [PDF]

open access: yes, 2006
A Bose-Einstein condensate (BEC) is a quantum fluid that gives rise to interesting shock wave nonlinear dynamics. Experiments depict a BEC that exhibits behavior similar to that of a shock wave in a compressible gas, eg.
A. V. Gurevich   +22 more
core   +3 more sources

Identifying transcription factors controlling the basal expression of human MRP4 highlights a substantial role for Sp1

open access: yesFEBS Open Bio, EarlyView.
The MRP4 transporter exports several drugs and signaling molecules. Here, we identified key promoter elements regulating basal MRP4 expression. Using reporter assays, we defined a conserved region with essential Sp1 and contributory Ets sites, which controlled basal MRP4 expression.
Debora Singer   +7 more
wiley   +1 more source

Rebaudi's stevia: Natural noncaloric sweeteners

open access: yesCalifornia Agriculture, 1982
Stevia, a Paraguayan plant that produces compounds 250 times as sweet as table sugar, is being studied for possible commercial production here.
C Shock
doaj  

13 Prognostication in super refractory status epilepticus: Preliminary results from an international survey study

open access: yesJournal of Clinical and Translational Science
OBJECTIVES/GOALS: Super refractory status epilepticus (SRSE) is associated with high mortality, often due to withdrawal of life sustaining therapy (WLST) based on perceived poor neurological prognosis.
Matthew R. Woodward   +5 more
doaj   +1 more source

Spinal Shock [PDF]

open access: yesMayo Clinic Proceedings, 1996
The term "spinal shock" applies to all phenomena surrounding physiologic or anatomic transection of the spinal cord that results in temporary loss or depression of all or most spinal reflex activity below the level of the injury. Hypotension due to loss of sympathetic tone is a possible complication, depending on the level of the lesion.
P P, Atkinson, J L, Atkinson
openaire   +2 more sources

Lipopolysaccharide uptake is augmented in lipopolysaccharide‐tolerant mouse macrophage‐like cells via increased CD14 expression

open access: yesFEBS Open Bio, EarlyView.
In normal (nontolerant) cells, CD14 is crucial for both LPS uptake and LPS signaling. In LPS‐tolerant cells, in which LPS‐induced TNF‐α and IFN‐β production is suppressed, there is a dramatic increase in surface CD14 expression. The overexpressed CD14 in LPS‐tolerant cells is responsible for the enhanced LPS uptake without inducing pro‐inflammatory ...
Saeka Nishihara   +3 more
wiley   +1 more source

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