Results 41 to 50 of about 1,246,503 (300)

Aquaporin‐3 and aquaporin‐5 impact the development of pancreatic ductal adenocarcinoma spheroids

FEBS Open Bio, EarlyView.
Schematic representation of the role of aquaporin‐3 (AQP3) and aquaporin‐5 (AQP5) in pancreatic ductal adenocarcinoma (PDAC). Both proteins are upregulated in PDAC and are associated with tumor progression and metastatic potential. Silencing AQP3 or AQP5 in PDAC spheroids results in decreased diameter, area, and overall growth, underscoring their key ...
Catarina Pimpão, Diogo M. Engrácia, Graça Soveral, Filipa Mendes   +3 more
wiley   +1 more source

An enhanced instantaneous detonation model for underwater explosions involving condensed explosives

Scientific Reports
The dynamic characteristics of underwater explosion phenomena, involving complex multi-phase and multi-interface motions such as shock wave propagation, charge detonation, and bubble motion, are typically predicted using compressible multiphase flow ...
Ji-ping Chen, Jun Wang, Hai-tao Li, Jian-qiang Pan, Hai-bin Mao, Jun Yu   +5 more
doaj   +1 more source

Molecular characterization of covRS mutations in M1UK Streptococcus pyogenes

FEBS Open Bio, EarlyView.
Group A Streptococcus (GAS) acquires covRS mutations driving a hypervirulent bacterial state, frequently associated with invasive disease‐like necrotizing fasciitis. We demonstrate that the newly emerged M1UK GAS lineage can also acquire these mutations.
Jarrad Pritchard, Emma‐Jayne Proctor, Jiawa Wang, Nikolas P. Johnston, Andrew Hayes, Georgia McCorkell, Haibo Yu, Jai Tree, Mark R. Davies, Mark J. Walker, Ronald Sluyter, Stephan Brouwer, Martina L. Sanderson‐Smith   +12 more
wiley   +1 more source

Severe Sepsis and Septic Shock: Timing of Septic Shock Onset Matters

, 2017
Introduction: Timing of septic shock onset may play a prognostic role in severe sepsis; however, clinical evidence provides contradictory results. This study aimed to investigate possible associations between timing of onset of septic shock and patient ...
余忠仁;柯文哲;黃俊達;蔡壁如, Huang, Chun-Ta;Tsai, Yi-Ju;Tsai, Pi-Ru;Yu, Chong-Jen;Ko, Wen-Je   +1 more
core   +1 more source

Immediate versus delayed weight bearing for fractures of the pelvis, acetabulum, distal femur, and proximal and distal tibia: a feasibility randomized controlled trial

Pilot and Feasibility Studies
Background Early weight bearing is frequently allowed and encouraged following fixation of hip and femoral and tibial shaft fractures, while pelvis, acetabulum, and lower extremity periarticular fractures are often prescribed 6–12 weeks of restricted ...
Peter N. Mittwede, Vivian Li, David O. Okhuereigbe, Alice C. Bell, Casey Loudermilk, Haley K. Demyanovich, Joshua E. Lawrence, Kristin E. Turner, Murali Kovvur, Jordan P. Brand, Daniel J. Cunningham, Daniel J. Johnson, Aresh Sepehri, Marcus F. Sciadini, Jason W. Nascone, Mark J. Gage, Eric C. Hempen, Nathan N. O’Hara, Gerard P. Slobogean, Robert V. O’Toole   +19 more
doaj   +1 more source

Shock Detectives: classifying MMS observations of Earth’s magnetosheath via citizen science

Frontiers in Astronomy and Space Sciences
We present a dataset of 35,483 unique 1 minute periods (∼591 h) of quasi-perpendicular and quasi-parallel magnetosheath MMS classifications manually reviewed with the help of citizen scientists.
Vicki Toy-Edens, Wenli Mo, Savvas Raptis, Nathan C. Bell, Magdalena Dąbrowska, Thorsten Eschweiler, Rachel A. Ford, Virgilio Gonano, Andrey C. R. B. Gorokhov, Jose Manuel Leal Quesada, Adeline M. Luperchio, Antonio Pasqua   +11 more
doaj   +1 more source

Hyperosmotic stress‐induced redistribution of pre‐mRNA cleavage factor I subunits is associated with shifts in alternative polyadenylation

FEBS Open Bio, EarlyView.
Hyperosmotic stress triggers the relocation of the CFIm complex from the nucleus to the cytoplasm. This shift creates a nuclear ‘stoichiometric bottleneck’, limiting CFIm availability for mRNA processing. Consequently, specific mRNAs like NUDT21 and DICER1 undergo targeted 3′UTR shortening, demonstrating how spatial protein dynamics drive rapid ...
Hitomi Soumiya, Masatake Osawa, Hidefumi Fukumitsu   +2 more
wiley   +1 more source

Rebaudi's stevia: Natural noncaloric sweeteners

California Agriculture, 1982
Stevia, a Paraguayan plant that produces compounds 250 times as sweet as table sugar, is being studied for possible commercial production here.
C Shock
doaj  

Effect of terahertz irradiation on DNA damage repair in living cells

FEBS Open Bio, EarlyView.
We investigated the effect of terahertz (THz) wave irradiation on DNA double‐strand break (DSB) repair in living cells. We found that THz irradiation enhanced DSB repair at specific frequencies, whereas heat treatment inhibited it, indicating that this effect is nonthermal and frequency‐specific.
Yuya Ueno, Shota Yamazaki, Hiromichi Hoshina, Masahiko Harata   +3 more
wiley   +1 more source

Numerical Study of Shock/Boundary Layer Interaction of Chemically Reacting Flow in Shock Tube [PDF]

, 2015
In this paper, a high-order Navier-Stokes solver is developed for chemically reacting flow and is applied to investigate the unsteady, viscous interaction between shock wave and boundary layer in an air filled shock tube.
Chen S(陈松), Sun QH(孙泉华)
core   +1 more source