Results 31 to 40 of about 2,480,958 (301)

Magnetohydrodynamic Simulation of the Interaction between Interplanetary Strong Shock and Magnetic Cloud and its Consequent Geoeffectiveness 2: Oblique Collision

open access: yes, 2009
Numerical studies of the interplanetary "shock overtaking magnetic cloud (MC)" event are continued by a 2.5 dimensional magnetohydrodynamic (MHD) model in heliospheric meridional plane.
Baker   +68 more
core   +1 more source

The planar cell polarity protein Vangl2 interacts with the PDZ‐domains of Scribble but not with a unique PDZ‐like domain in Inturned

open access: yesFEBS Letters, EarlyView.
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes   +4 more
wiley   +1 more source

Transmission and Emission of Solar Energetic Particles in Semi-transparent Shocks. [PDF]

open access: yes, 2014
While major solar energetic particle (SEP) events are associated with coronal mass ejection (CME)-driven shocks in solar wind, accurate SEP measurements reveal that more than one component of energetic ions exist in the beginning of the events.
Axford   +21 more
core   +1 more source

Combining antibody conjugates with cytotoxic and immune‐stimulating payloads maximizes anti‐cancer activity

open access: yesMolecular Oncology, EarlyView.
Methods to improve antibody–drug conjugate (ADC) treatment durability in cancer therapy are needed. We utilized ADCs and immune‐stimulating antibody conjugates (ISACs), which are made from two non‐competitive antibodies, to enhance the entry of toxic payloads into cancer cells and deliver immunostimulatory agents into immune cells.
Tiexin Wang   +3 more
wiley   +1 more source

A Neural Network Method for Land Use Change Classification, with Application to the Nile River Delta [PDF]

open access: yes, 2001
Detecting and monitoring changes in conditions at the Earth's surface are essential for understanding human impact on the environment and for assessing the sustainability of development. In the next decade, NASA will gather high-resolution multi-spectral
Carpenter, Gail   +3 more
core   +1 more source

Pre‐analytical optimization of cell‐free DNA and extracellular vesicle‐derived DNA for mutation detection in liquid biopsies

open access: yesMolecular Oncology, EarlyView.
Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen   +11 more
wiley   +1 more source

Numerical investigation on unsteady force suppression of pump-jet rotor by oscillating stator trailing edge flaps

open access: yesZhongguo Jianchuan Yanjiu, 2023
ObjectivesThe unsteady force of the rotor is the main excitation source of pump-jet shafting vibration, and rotor-stator interaction has an important impact on the characteristics of the unsteady force.
Wanghao TANG   +3 more
doaj   +1 more source

Shock dynamics in non-uniform media [PDF]

open access: yes, 1983
The theory of shock dynamics in two dimensions is reformulated to treat shock propagation in a non-uniform medium. The analysis yields a system of hyperbolic equations with source terms representing the generation of disturbances on the shock wave as it ...
Catherasoo, C. J., Sturtevant, B.
core   +1 more source

Revisiting Mission‐Oriented Cancer Research to tackle the increasing burden of cancer in Europe–a policy perspective

open access: yesMolecular Oncology, EarlyView.
Translational cancer research and its implementation through competitively selected Comprehensive Cancer Centers across Europe should be the primary policy focus for addressing the increasing cancer burden in Europe and counteract the present main strategy to convert cancer to a chronic disease.
Manuel Heitor   +2 more
wiley   +1 more source

ARTMAP Neural Network Classification of Land Use Change [PDF]

open access: yes, 2001
The ability to detect and monitor changes in land use is essential for assessment of the sustainability of development. In the next decade, NASA will gather high-resolution multi-spectral and multi-temporal data, which could be used for detecting and ...
Carpenter, Gail   +3 more
core   +1 more source

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