Results 151 to 160 of about 990,795 (392)

Functional Materials Targeted Regulation of Gasdermins: From Fundamentals to Functionalities and Applications

Advanced Science, EarlyView.
Targeted regulation of pyroptosis to modulate the immune landscape is a novel design strategy for cancer immunotherapy and anti‐inflammatory treatment. Pyroptosis, as a double‐edged sword, underscores the importance of optimizing the design strategy of functional materials and appropriately activating pyroptosis for the effective treatment of diseases.
Luyao Tian, Shuo Piao, Xia Li, Lanping Guo, Luqi Huang, Wenyuan Gao   +5 more
wiley   +1 more source

Ventricular assist device implantation in the elderly [PDF]

, 2014
BACKGROUND: Dramatic advances in ventricular assist device (VAD) design and patient management have made mechanical circulatory support an attractive therapeutic option for the growing pool of elderly heart failure patients.
Boyd, Jack H., Hiesinger, William, Woo, Y. Joseph   +2 more
core   +1 more source

Microenvironmental Modulation for Therapeutic Efficacy of Extracellular Vesicles

Advanced Science, EarlyView.
Recent studies highlighted the heterogeneity of EVs and the influence of microenvironmental signals on their therapeutic efficacy. This review offers a comprehensive overview of strategies and mechanisms to optimize the therapeutic efficacy of EVs through physical, biochemical, and mechanical modulation.
Bilu Xiang, Shiying Zhang, Irene Shuping Zhao, Xueqi Gan, Yang Zhang   +4 more
wiley   +1 more source

Impellent impeller—Switching intra‐aortic balloon pump to IMPELLA‐CP after ST‐segment elevation myocardial infarction and refractory cardiogenic shock

Clinical Case Reports, 2019
Cardiogenic shock is a dreadful complication of myocardial infarction. Despite widespread use and availability, intra‐aortic balloon pump (IABP) does not reduce mortality nor improves outcomes.
Marco Contarini, Francesco Costa, Maria Victoria Garcia Ruiz, Renato F. M. Scalise, Giovanni De Velli, Paola Murè, Paolo Mazzone, Giorgio Sacchetta, Giuseppe Andò   +8 more
doaj   +1 more source

Acute Biventricular Mechanical Circulatory Support for Cardiogenic Shock

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2017
BackgroundBiventricular failure is associated with high in‐hospital mortality. Limited data regarding the efficacy of biventricular Impella axial flow catheters (BiPella) support for biventricular failure exist.
Sudeep Kuchibhotla, Michele L. Esposito, Catalina Breton, Robert Pedicini, Andrew Mullin, Ryan O'Kelly, Mark Anderson, Dennis L. Morris, George Batsides, Danny Ramzy, Mark Grise, Duc Thinh Pham, Navin K. Kapur   +12 more
doaj   +1 more source

Implementation of anaphylaxis management guidelines [PDF]

, 2012
Anaphylaxis management guidelines recommend the use of intramuscular adrenaline in severe reactions, complemented by antihistamines and corticoids; secondary prevention includes allergen avoidance and provision of self-applicable first aid drugs.
Gough, Hannah, Grabenhenrich, Linus, Hawranek, Thomas, Hompes, Stephanie, Keil, Thomas, Koehli, Alice, Mahler, Vera, Nemat, Katja, Pföhler, Claudia, Ruëff, Franziska, Scherer, Kathrin, Treudler, Regina, Worm, Margitta   +12 more
core   +1 more source

Moisture Harvesting by the Structure Regulation of Hygroscopic Hydrogel for Energy and Water Sustainability

Advanced Electronic Materials, EarlyView.
Hygroscopic hydrogels are capable of utilizing the moisture from air, which can transfer the gaseous water to liquid by a surface phase transition. Taking advantage of this water, sustainable water production, thermal management, and electricity generation can be realized.
Yujie Du, Yongliang Zheng, Hong Liu, Shujing Zhao, Xiaomian Wang, Lin Yang   +5 more
wiley   +1 more source

The brain‐before‐heart strategy for coronary artery bypass grafting in the severely atherosclerotic aorta: A single‐institution experience

Clinical Cardiology, Volume 45, Issue 12, Page 1264-1271, December 2022., 2022
Abstract Background Severe atherosclerosis of the ascending aorta (SAA) in patients undergoing surgical revascularization by coronary artery bypass grafting (CABG) is becoming an increasing problem as more elderly patients are diagnosed with coronary artery disease.
Rakan I. Nazer, Ali M. Albarrati
wiley   +1 more source

Stress Cardiomyopathy Managed with Extracorporeal Support after Self-Injection of Epinephrine

Case Reports in Critical Care, 2017
A 28-year-old man was admitted to the ICU for self-injection of Epinephrine. This injection resulted in the rapid development of a catecholamine-induced cardiomyopathy (inverted Takotsubo) with a severe cardiogenic shock.
Bourenne Jeremy, Fresco Raphaëlle, Kerbaul François, Michelet Pierre, Gainnier Marc   +4 more
doaj   +1 more source

Real-life use of left ventricular circulatory support with Impella in cardiogenic shock after acute myocardial infarction: 12 years AMC experience

European heart journal. Acute cardiovascular care, 2018
Aims: Mortality in cardiogenic shock patients remains high. Short-term mechanical circulatory support with Impella can be used to support the circulation in these patients, but data from randomised controlled studies and ‘real-world’ data are sparse. The
D. Ouweneel, J. D. Brabander, M. Karami, K. Sjauw, A. Engström, M. Vis, J. Wykrzykowska, M. Beijk, K. Koch, J. Baan, R. J. Winter, J. Piek, W. Lagrand, T. Cherpanath, A. Driessen, Riccardo Cocchieri, B. Mol, J. Tijssen, J. Henriques   +18 more
semanticscholar   +1 more source