Results 121 to 130 of about 908,035 (248)

OTUD6A‐Mediated Deubiquitination of PRDX1 Protects Against Oral Ulcer by Restoring Mitochondrial Function

Advanced Science, EarlyView.
In human oral keratinocytes, OTUD6A promoted cell migration by deubiquitinating and stabilizing PRDX1. Conversely, OTUD6A deficiency reduced PRDX1 stability, triggering mitochondrial dysfunction and aggravating OU progression. ABSTRACT Oral ulcers (OU), as the most highly prevalent and recurrent oral mucosal lesion, have an unclear pathogenesis that ...
Xiaoyu Sun, Ruiwei Jia, Xingbei Pan, Rui Huang, Jiahong Chen, Ziyi Yao, Lei Yin, Jun Ma, Hongjieliang Wang, Xinyu Huang, Yilin Ma, Yifan Ping, Yuanyuan Chen, Huining Wang, Shengbin Huang, Guang Liang   +15 more
wiley   +1 more source

Numerical study of the influence of the rupture of burst discs on shock wave propagation in hydrogen-oxygen detonation tube

Case Studies in Thermal Engineering
Hydrogen-oxygen detonation tube has a wide range of applications. However, the role of burst discs is often oversimplified, overlooking the detrimental effects of their non-ideal rupture on shock wave propagation.
Yuhan Song, Xiangfeng Chen, Xinyu Yang, Kai Cao, Ming Fu, Xiaoyong Liu, Yayun Li   +6 more
doaj   +1 more source

Endothelial miR‐15a/16‐1 Regulation of SYNE1 Mediates Structural and Functional Recovery after Traumatic Brain Injury

Advanced Science, EarlyView.
Endothelial miR‐15a/16‐1 deletion promotes long‐term recovery after traumatic brain injury by restoring SYNE1 expression. Enhanced endothelial SYNE1 preserves vascular integrity, protects white and gray matter, and improves neurological function. The endothelial miR‐15a/16‐1–SYNE1 axis emerges as a key regulator of neurovascular repair and a potential ...
Shun Li, Na Qiu, Chao Zhou, Andrew Ni, Ping Sun, Jia‐Jun Liu, Xin‐Lei Huang, Tian‐Qing Xiong, Yu‐Chi Zhang, Hai‐Zhou Liu, Xiao‐Tao Xu, Rui Wang, Shi‐Qing Zhang, Yu‐Xin Zhang, Silvia Liu, C. Edward Dixon, Jun Chen, Ke‐Jie Yin   +17 more
wiley   +1 more source

A shock tube method in the kinetic study of nonequilibrium ionization-recombination by rarefaction wave cooling

, 2004
A shock tube method is introduced to study the ionization–recombination kinetics of high temperature gas, in which a test gas is heated and ionized by a reflected shock wave and subsequently quenched by a strong rarefaction wave reflected on the end wall
王苏, 崔季平, 何宇中, 范秉诚
core   +2 more sources

Computational Investigations and Control of Shock Interference

Applied Sciences
Computational fluid dynamics (CFD) has aided the development, design, and analysis of hypersonic airbreathing propulsion technologies, such as scramjets. The complex flow field in a scramjet isolator has been the subject of intense interest and study for
Cameron Alexander, Ragini Acharya
doaj   +1 more source

RNA Promotes Synapsin Condensates That Organize Synaptic Vesicles in Live Neurons and Enable Localized Translation in Reconstituted System

Advanced Science, EarlyView.
Condensates at synapses organize synaptic vesicles (SVs) and are crucial for efficient neurotransmitter release, yet how RNA contributes to this mesoscale architecture remains poorly understood. Here we uncover that RNA modulates synapsin–driven condensates.
Branislava Rankovic, Zachary M. Geisterfer, Akshita Chhabra, Vladimir M. Jovanovic, Ian Seim, Christian Hoffmann, Antonela Condric, Gerard Aguilar Pérez, Rinse de Boer, Lars T. Hofstede, Jingao Sun, Kiara Freitag, Katja Nowick, Marina Jendrach, Frank L. Heppner, Vladimir Despic, Michaela Müller‐McNicoll, Stephan Sigrist, Geert van den Bogaart, Sofiia Reshetniak, Amy S. Gladfelter, Dragomir Milovanovic   +21 more
wiley   +1 more source

Investigating the use of low and high-density polyethylene blends with waste material from three-layer factory tube for the third layer of shock tubes

Frontiers in Chemistry
Polymeric shock tubes are now widely used in explosives systems for drilling and mining operations. Most shock tubes on the market consist of three layers of polymer, the first layer being Surlyn 8940 copolymer, the second layer Nucrel 31001 and the ...
Ali Khalili Gashtroudkhani, Mohammad Dahmardeh Ghaleno, Saeed Soltan Abadi, Maryam Pouyani   +3 more
doaj   +1 more source

Youngstown Sheet and Tube Company's Indiana Harbor Works

, 1920
Youngstown Sheet and Tube Company's Indiana Harbor Works standing on the shores of Lake Michigan in East Chicago, Indiana, ca. 1920-1929. James A. Campbell purchased the Indiana Harbor Works in 1923 as part of an expansion of the Youngstown Sheet and ...
Youngstown Sheet and Tube Company
core  

Versatile Co‐Engineering of Immunogenic Cell Death‐Primed Dead Tumor Cell Bodies With Tumor‐Activated MnO2 for cGAS‐STING‐Potentiated Personalized Immunotherapy

Advanced Science, EarlyView.
DTBEI@CS@MnO2, fabricated via modular electrostatic co‐engineering and photothermal/photodynamic immunogenic cell death, specifically responds to the acidic and GSH‐rich tumor microenvironment. This triggers the release of DTBEI that provides tumor antigens, DNA, and DAMPs, as well as the generation of Mn2+, thereby synergistically potentiating cGAS ...
Bolun Xu, Xuan Lu, Yuquan Wang, Haihua Ji, Ying Zhang, Yiqun Wan, Hao Wan   +6 more
wiley   +1 more source

Influence of piston nonuniformity and illumination on the formation of a hypersonic shock wave in a laser-driven shock wave

Российский технологический журнал
Objectives. The study investigates the influence of inhomogeneities of laser flux intensity and piston (mylar film) thickness in a laser shock tube by comparing the conditions for the formation and dynamics of shock wave propagation in a laser shock tube
I. G. Lebo, V. A. Komarova, M. A. Ryzhkov   +2 more
doaj   +1 more source