Results 91 to 100 of about 584,928 (206)

Activation of Glutamatergic Neurons in the Supramammillary Nucleus Promotes the Recovery of Consciousness under Sevoflurane Anesthesia

Advanced Science, EarlyView.
Selective lesioning of SuM glutamatergic neurons promoted the induction of and delayed emergence from sevoflurane anesthesia and increased sevoflurane sensitivity. Optogenetic stimulation of SuM glutamatergic neurons or the SuM‐MS projection promoted behavioral arousal and cortical activation under steady‐state sevoflurane anesthesia and reduced the ...
Jiayan Li, Yehui Wu, Yihan Wang, Yumin Wu, Rong Hu, Si Long, Wenqi Huang, Liming Nie, Zhongxing Wang   +8 more
wiley   +1 more source

The Heliospheric Termination Shock [PDF]

arXiv, 2008
The heliospheric Termination Shock is the largest (by dimension) shock in the heliosphere. It is believed that it is also the strongest shock and is responsible for the generation of the Anomalous Cosmic Ray component in the heliosphere. This chapter review the gross properties and observations of the Termination Shock.
arxiv  

SIRT3‐Mediated Deacetylation of DRP1K711 Prevents Mitochondrial Dysfunction in Parkinson's Disease

Advanced Science, EarlyView.
SIRT3‐mediated deacetylation of DRP1 at K711 resists mitochondrial dysfunction and DA neuronal death in PD, uncovering a treatment target. Abstract Dysregulation of mitochondrial dynamics is a key contributor to the pathogenesis of Parkinson's disease (PD).
Ye Xi, Kai Tao, Xiaomin Wen, Dayun Feng, Zifan Mai, Hui Ding, Honghui Mao, Mingming Wang, Qian Yang, Jie Xiang, Jie Zhang, Shengxi Wu   +11 more
wiley   +1 more source

Implantable Self‐Powered Systems for Electrical Stimulation Medical Devices

Advanced Science, EarlyView.
In this paper, the design strategy and clinical application of ISS are discussed in depth from four aspects: the design and optimization of the energy collection module, the selection and preparation of adaptive electrode materials, the innovation of system design strategy, and the biological effect of electrical stimulation of ISS.
Xi Cui, Li Wu, Chao Zhang, Zhou Li
wiley   +1 more source

Autophagy Related 5 Promotes Mitochondrial Fission and Inflammation via HSP90‐HIF‐1α‐Mediated Glycolysis in Kidney Fibrosis

Advanced Science, EarlyView.
When the normal kidney is subjected to injurious stimuli, it can lead to persistent activation of ATG5. The activation of ATG5 promotes HSP90‐HIF‐1α interaction, resulting in stabilization of HIF‐1α and subsequent activation of glycolysis. Consequently, this process contributes to mitochondrial fission and inflammation, ultimately culminating in kidney
Yan Hu, Jinqing Li, Hui Chen, Yingfeng Shi, Xiaoyan Ma, Yi Wang, Xialin Li, Qin Zhong, Yishu Wang, Daofang Jiang, Shougang Zhuang, Na Liu   +11 more
wiley   +1 more source

MXene‐Supported Single‐Atom Electrocatalysts

Advanced Science, EarlyView.
This review discusses the characteristics and synthesis of MXenes to elucidate their benefits as support materials. Next, methods and characterization for anchoring SAs onto MXene are discussed. Subsequently, a comprehensive discussion is provided on the recent applications of MXene‐supported SACs in electrocatalysis. Finally, the future challenges and
Jianan He, Joshua D. Butson, Ruijia Gu, Adrian Chun Minh Loy, Qining Fan, Longbing Qu, Gang Kevin Li, Qinfen Gu   +7 more
wiley   +1 more source

Assembly and Functionality of 2D Protein Arrays

Advanced Science, EarlyView.
2D protein arrays‐based outstanding properties, including their remarkable structural stability, exceptional physiochemical properties, and tunable electronic and mechanical attributes, have become a key functional platform for developing advanced functional materials.
Mingming Du, Fanmeng Zeng, YueFei Wang, Ying Li, Guangcun Chen, Jiang Jiang, Qiangbin Wang   +6 more
wiley   +1 more source

Popular political attitudes in Samoa: Findings of the Pacific Attitudes Survey

Asia &the Pacific Policy Studies, Volume 9, Issue 3, Page 408-429, September 2022., 2022
Abstract Popular political attitudes surveys have been conducted globally for several decades, but the Pacific region remains an exception. This paper presents the findings of the first Pacific Attitudes Survey (PAS), conducted in Samoa from December 2020‐January 2021.
Michael Leach, Julien Barbara, Ioana Chan Mow, Sina Vaai, Christopher Mudaliar, Patila Amosa, Louise Mataia, Susana Tauaa, Taema Imo, Vernetta Heem   +9 more
wiley   +1 more source

Three‐State Thermochromic Smart Window for Building Energy‐Saving

Advanced Science, EarlyView.
A unique three‐state thermochromic smart window (TSSW) featuring W‐VO₂ and perovskite adapts to cold, warm, and hot states, dynamically modulating visible and NIR transmittance across the solar spectrum for superior energy efficiency. Abstract Smart windows that dynamically regulate solar spectrum transmission to reduce energy consumption in heating ...
Meiling Liu, Xiansheng Li, Wenshuo Zhang, Lanxin Li, Liang Li, Chengming Wang, Gang Pei, Bin Zhao, Chongwen Zou   +8 more
wiley   +1 more source

COVID‐19 in the Pacific territories: Isolation, borders and the complexities of governance

Asia &the Pacific Policy Studies, Volume 9, Issue 3, Page 394-407, September 2022., 2022
Abstract Early experience of COVID‐19 in seven Pacific politically dependent territories (Guam, American Samoa, Pitcairn, Tokelau, French Polynesia, Wallis and Futuna, and New Caledonia) emphasises a diversity of contexts, responses, outcomes and possible futures.
John Connell
wiley   +1 more source