Results 61 to 70 of about 3,477 (212)
Physics and Imaging in Radiation OncologyBackground and purpose: Very High-Energy Electron (VHEE) radiotherapy stands as a promising alternative to proton therapy in view of the FLASH effect, which allows for differential sparing of healthy tissues under ultra-high dose rate irradiation.
Flavia Gesualdi +7 more
doaj +1 more source
Directed evolution of enzymes at the crossroads of tradition and innovation
FEBS Open Bio, EarlyView.An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova +2 more
wiley +1 more source
Value of MRI Outcomes for Preventive and Early‐Stage Trials in Spinocerebellar Ataxias 1 and 3
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective To examine the value of MRI outcomes as endpoints for preventive and early‐stage trials of two polyglutamine spinocerebellar ataxias (SCAs). Methods A cohort of 100 participants (23 SCA1, 63 SCA3, median Scale for the Assessment and Rating of Ataxia (SARA) score = 5, 42% preataxic, and 14 gene‐negative controls) was scanned at 3T up ...
Thiago J. R. Rezende +26 more
wiley +1 more source
In vitro regeneration of Centaurium erythraea Rafn from shoot tips and other seedling explants
Acta Societatis Botanicorum Poloniae, 2011 Various explants from 30-day-old seedlings of Centaurium erythraea Rafn were evaluated for their morphogenetic capacity under in vitro culture conditions.
Ewelina Piątczak, Halina Wysokińska
doaj +1 more source
EFFORTS TO IMPROVE FUTSAL SHOOTING THROUGH GAME VARIATIONS
Gladi : Jurnal Ilmu KeolahragaanThis research is action research to improve shooting skills in futsal games in class V and VI students who are registered as futsal extracurricular participants at SDN Srengseng Sawah 04 with a total of 53 students as subjects. This action research uses the Kemmis Taggart model which consists of two cycles. The actions in this research use a variety of
Yusuf, Ramdan Muhammad +2 more
openaire +2 more sources
Screening Routine Clinical Notes for Epilepsy Surgery Candidates Using Large Language Models
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Epilepsy surgery is severely underutilized despite proven efficacy, with substantial under‐referral of eligible patients in routine clinical practice. This study evaluated the potential role of large language models (LLMs) as decision‐support tools for screening unstructured clinical notes to identify epilepsy surgery candidates and ...
Uriel Fennig +9 more
wiley +1 more source
A 17 Year Old With Developmental Delay Presenting With Increasing Confusion and Imbalance
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Methylmalonic acidemia is an autosomal recessive genetic disorder primarily caused by defects in methylmalonyl‐CoA mutase and cobalamin (vitamin B12) metabolism. These defects disrupt the tricarboxylic acid cycle and oxidative phosphorylation, leading to the abnormal accumulation of metabolic products such as methylmalonic acid, propionic acid,
Wei Zhao, Yingli Zhang, Hongliang Zheng
wiley +1 more source
Cálculo de Esforço nos Semicondutores do Inversor Fonte Z
Eletrônica de Potência, 2016 Este trabalho apresenta o cálculo dos esforços de corrente nos semicondutores do inversor fonte Z trifásico operando com a modulação Boost Simples. O inversor fonte Z possui uma malha de impedância conhecida como malha Z, que possibilita realizar as ...
Vitor T. Odaguiri +2 more
doaj +1 more source
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Neurochemical levels measured by brain MR spectroscopy (MRS) have been proposed as endpoints for clinical trials in early‐stage spinocerebellar ataxia (SCA) trials. We tested their trial‐readiness by quantifying neurochemicals in three affected brain regions in early‐stage cohorts of SCA2 and SCA3, examining their reproducibility in ...
James M. Joers +19 more
wiley +1 more source
IEEE Access, 2020 In a single-stage buck-boost quasi-switched boost inverter (qSBI), the shoot-through state insertion causes high amplitude common-mode voltage. Consequently, the qSBI becomes less attractive in transformerless photovoltaic (PV) systems.
Truong-Duy Duong +5 more
doaj +1 more source