Results 51 to 60 of about 3,477 (212)

Phosphoinositides and inositol phosphates as molecular glues

open access: yesFEBS Letters, EarlyView.
Inositol phosphates (IPs) and phosphoinositides (PIPs) regulate diverse eukaryotic processes. Beyond recruiting signaling proteins or acting as structural cofactors, recent studies suggest they mediate protein–protein interactions as natural molecular glues.
Aleshia Seaton‐Terry   +9 more
wiley   +1 more source

Morpho-histological analysis of shoot regeneration and large-scale propagation of an endangered species Rhododendron mucronulatum Turcz. [PDF]

open access: yesСибирский лесной журнал, 2018
An efficient system for the in vitro propagation of the endangered medicinal and winter-hardy ornamental plant, Rhododendron mucronulatum Turcz., through high frequency shoot induction from seedlings and in vitro-derived apical shoots was developed ...
Yu. G. Zaytseva, T. I. Novikova
doaj   +1 more source

Transcriptomics and metabolomics reveal effect of arbuscular mycorrhizal fungi on growth and development of apple plants

open access: yesFrontiers in Plant Science, 2022
Arbuscular mycorrhizal fungi (AMF) and plants form a symbiotic relationship that promotes plant growth and development. However, the regulatory mechanisms through which AMF promote plant growth and development are largely unexplored.
Shan Jing   +9 more
doaj   +1 more source

Pre‐analytical optimization of cell‐free DNA and extracellular vesicle‐derived DNA for mutation detection in liquid biopsies

open access: yesMolecular Oncology, EarlyView.
Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen   +11 more
wiley   +1 more source

Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining

open access: yesMolecular Oncology, EarlyView.
IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis   +3 more
wiley   +1 more source

Ex Situ Conservation of Atriplex taltalensis I.M. Johnst. via In Vitro Culturing of Its Axillary Shoots

open access: yesDiversity, 2022
Atriplex taltalensis is an endangered shrub endemic to northern Chile. Sparse populations of this species can be found in areas with extreme edaphoclimatic conditions in the Atacama desert, and its seeds have a poor germination rate.
Carolina Muñoz-Alcayaga   +3 more
doaj   +1 more source

Dissipation Loop for Shoot-Through Faults in HVDC Converter Cells

open access: yes2018 International Power Electronics Conference (IPEC-Niigata 2018 -ECCE Asia), 2018
Converter cells for HVDC applications store large amounts of energy. This energy might be dissipated in a very short time in case of a shoot-through fault. Measures to avoid shoot-through or handle the extreme currents during a fault and prevent damage from neighboring components are essential to ensure a continued operation of the converter.
Jacobs, Keijo   +2 more
openaire   +3 more sources

Polarization‐resolved femtosecond Vis/IR spectroscopy tailored for resolving weak signals in biological samples using minimal sample volume

open access: yesFEBS Open Bio, EarlyView.
Unique biological samples, such as site‐specific mutant proteins, are available only in limited quantities. Here, we present a polarization‐resolved transient infrared spectroscopy setup with referencing to improve signal‐to‐noise tailored towards tracing small signals. We provide an overview of characterizing the excitation conditions for polarization‐
Clark Zahn, Karsten Heyne
wiley   +1 more source

Micropropagation of Plantago asiatica L. through culture of shoot-tips

open access: yesActa Societatis Botanicorum Poloniae, 2011
Shoot-tip multiplication of the medicinal species - Plantago asiatica was carried on MS medium with IAA and BAP or kinetin. Best results in micropropagation were achieved by adding 0.1 mg/dm3 IAA and 1 mg/dm3 BAP. After 6 weeks shoots were transferred to
Joanna Makowczyńska   +1 more
doaj   +1 more source

Identifying transcription factors controlling the basal expression of human MRP4 highlights a substantial role for Sp1

open access: yesFEBS Open Bio, EarlyView.
The MRP4 transporter exports several drugs and signaling molecules. Here, we identified key promoter elements regulating basal MRP4 expression. Using reporter assays, we defined a conserved region with essential Sp1 and contributory Ets sites, which controlled basal MRP4 expression.
Debora Singer   +7 more
wiley   +1 more source

Home - About - Disclaimer - Privacy