Results 241 to 250 of about 532,861 (306)

A dsRNA Viral Transcriptional Regulator Evades Innate Immunity by Hijacking Host CoTranscription Factor DHX9

Advanced Science, EarlyView.
This study identifies a new viral mechanism by a viral protein σ3 that functions as a vTR to suppress NF‐κB gene expression via its direct interaction with the host helicase DHX9. Through their interaction, σ3 not only impairs the initial recruitment of Pol II but also affects Pol II pause‐release and ultimately suppresses NF‐κB gene expression ...
Xueyang Pang, Shiyu Liu, Yixiao Zhu, Meleana M. Hinchman, Nan Qiao, Xuejun Li, Weiqian Dai, Yingying Tong, Man Xing, Jiling Ren, John S. L. Parker, Yingying Guo, Dongming Zhou   +12 more
wiley   +1 more source

Activating the Osteoblastic USP26 Pathway Alleviates Multi‐Organ Fibrosis by Decreasing Insulin Resistance

Advanced Science, EarlyView.
The loss of Ubiquitin Specific Peptidase 26 (USP26) in osteoblasts results in decreased bone formation, as well as multi‐organ fibrosis associated with insulin resistance (IR). Mechanistically, the absence of USP26 reduces glycolysis and lactate accumulation, leading to decreased histone H3 lysine 18 lactylation (H3K18LA) in the promoter region of KH ...
Jiyuan Tang, Wenkai Ye, Liang He, Zhou Dan, Leilei Chang, Zijie You, Yuanyue Jiang, Guoqing Tang, Lianfu Deng, Changwei Li   +9 more
wiley   +1 more source

Deep Learning and Machine Learning Modeling Identifies Thidiazuron as a Key Modulator of Somatic Embryogenesis and Shoot Organogenesis in <i>Ferula assa-foetida</i> L. [PDF]

Biology (Basel)
Kumari K, Mittal S, Sharma K, Singh S, Upadhyay J, Acharya V, Kadyan V, Yadav SK, Joshi R.   +8 more
europepmc   +1 more source

Quasi‐Periodic Porous Structures‐Based Temperature and Pressure Dual‐Mode Electronic Skin for Material Cognition

Advanced Science, EarlyView.
A quasi‐periodic porous structure‐based temperature and pressure dual‐mode electronic skin was proposed. Benefiting from the quasi‐periodic porous structure, the temperature and pressure sensing performance of the electronic skin can be precisely constructed and optimized by changing the size of the porous structure. By analyzing the thermoelectric and
Xiaoguang Gao, Chengzhen Xue, Xiaoliang Zhang, Xuejuan Meng, Xiaochun Li, Li Niu   +5 more
wiley   +1 more source

A virtual reality test to evaluate dismounted soldiers' cognitive and psychomotor performance in an operationally relevant setting. [PDF]

Front Psychol
Koedijk M, Landman A, Bottenheft C, Fonken YM, Binsch O.   +4 more
europepmc   +1 more source

Distribution, Growth, and Phosphorus Relationships of Water Milfoil in Lake Winnipesaukee, New Hampshire [PDF]

, 1979
Baker, Alan L., Chagnon, Ellen
core   +1 more source

Diffusion‐MRI‐Based Estimation of Cortical Architecture via Machine Learning (DECAM) in Primate Brains

Advanced Science, EarlyView.
We present Diffusion‐MRI‐based Estimation of Cortical Architecture via Machine Learning (DECAM), a deep‐learning framework for estimating primate brain cortical architecture optimized with best response constraint and cortical label vectors. Trained using macaque brain high‐resolution multi‐shell dMRI and histology data, DECAM generates high‐fidelity ...
Tianjia Zhu, Minhui Ouyang, Shufang Tan, Jianlin Guo, Ziqin Zhang, Xuan Liu, Risheng Liu, Hao Huang   +7 more
wiley   +1 more source

Optimizing Daily Light Integral in Seedling Stage Accelerates Heading and Flowering in Wheat Under LED Lighting. [PDF]

Plants (Basel)
Zhong L, Ji X, Liu J, Zhou Q, He D.
europepmc   +1 more source

CLinNET: An Interpretable and Uncertainty‐Aware Deep Learning Framework for Multi‐Modal Clinical Genomics

Advanced Science, EarlyView.
Identifying disease‐causing genes in neurocognitive disorders remains challenging due to variants of uncertain significance. CLinNET employs dual‐branch neural networks integrating Reactome pathways and Gene Ontology terms to provide pathway‐level interpretability of genomic alterations.
Ivan Bakhshayeshi, Mohammad Mahdi Hosseini, Ahmadreza Argha, Roxana Zahedi, Nigel H. Lovell, Hamid Alinejad‐Rokny   +5 more
wiley   +1 more source