Results 61 to 70 of about 97,868 (303)

Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining

open access: yesMolecular Oncology, EarlyView.
IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis   +3 more
wiley   +1 more source

In vitro regeneration of Centaurium erythraea Rafn from shoot tips and other seedling explants

open access: yesActa Societatis Botanicorum Poloniae, 2011
Various explants from 30-day-old seedlings of Centaurium erythraea Rafn were evaluated for their morphogenetic capacity under in vitro culture conditions.
Ewelina Piątczak, Halina Wysokińska
doaj   +1 more source

Polarization‐resolved femtosecond Vis/IR spectroscopy tailored for resolving weak signals in biological samples using minimal sample volume

open access: yesFEBS Open Bio, EarlyView.
Unique biological samples, such as site‐specific mutant proteins, are available only in limited quantities. Here, we present a polarization‐resolved transient infrared spectroscopy setup with referencing to improve signal‐to‐noise tailored towards tracing small signals. We provide an overview of characterizing the excitation conditions for polarization‐
Clark Zahn, Karsten Heyne
wiley   +1 more source

Adaptive shoot-through duty ratio control methodology of stand-alone quasi Z-source inverter

open access: yes, 2023
This paper presents an adaptive shoot-through duty ratio control methodology for a stand-alone three-phase quasi-Z-source inverter (qZSI). In practice, variable active and reactive load powers must be met by a qZSI-based stand-alone system.
Das, Sudip   +3 more
core   +1 more source

Identifying transcription factors controlling the basal expression of human MRP4 highlights a substantial role for Sp1

open access: yesFEBS Open Bio, EarlyView.
The MRP4 transporter exports several drugs and signaling molecules. Here, we identified key promoter elements regulating basal MRP4 expression. Using reporter assays, we defined a conserved region with essential Sp1 and contributory Ets sites, which controlled basal MRP4 expression.
Debora Singer   +7 more
wiley   +1 more source

Dissipation Loop for Shoot-Through Faults in HVDC Converter Cells

open access: yes, 2018
Converter cells for HVDC applications store large amounts of energy. This energy might be dissipated in a very short time in case of a shoot-through fault.
Jacobs, Keijo,   +5 more
core   +1 more source

Cálculo de Esforço nos Semicondutores do Inversor Fonte Z

open access: yesEletrônica de Potência, 2016
Este trabalho apresenta o cálculo dos esforços de corrente nos semicondutores do inversor fonte Z trifásico operando com a modulação Boost Simples. O inversor fonte Z possui uma malha de impedância conhecida como malha Z, que possibilita realizar as ...
Vitor T. Odaguiri   +2 more
doaj   +1 more source

Directed evolution of enzymes at the crossroads of tradition and innovation

open access: yesFEBS Open Bio, EarlyView.
An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova   +2 more
wiley   +1 more source

Shoot-through protection for an inverter consisting of the next-generation IGBTs with gate impedance reduction

open access: yes, 2020
Attention has been paid to the next-generation IGBT toward CMOS compatible wafer processes, which can be driven by a 5-V logic level due to its low threshold gate voltage. This low threshold voltage makes the so-called shoot-through fault severer.
16176   +23 more
core   +1 more source

Modulation Techniques for a Modified Three-Phase Quasi-Switched Boost Inverter With Common-Mode Voltage Reduction

open access: yesIEEE Access, 2020
In a single-stage buck-boost quasi-switched boost inverter (qSBI), the shoot-through state insertion causes high amplitude common-mode voltage. Consequently, the qSBI becomes less attractive in transformerless photovoltaic (PV) systems.
Truong-Duy Duong   +5 more
doaj   +1 more source

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