Results 231 to 240 of about 308,842 (252)

Innovations in Short-Read Sequencing Technologies and Their Applications to Clinical Genomics

Clinical Chemistry
Abstract Background Massively parallel sequencing (MPS) of nucleic acids has been a transformative technology for basic and applied genomic science, increasing efficiencies and decreasing costs to enable studies of unprecedented scope and impact.
Katarzyna Polonis, Joseph H Blommel, Andrew E O Hughes, David Spencer, Joseph A Thompson, Molly C Schroeder   +5 more
openaire   +2 more sources

HLA Typing from Short-Read Sequencing Data with OptiType

2018
The established standards for HLA genotyping rely on targeted DNA sequencing techniques. However, the increasing abundance of short-read sequencing data has prompted a demand for computational tools capable of HLA typing from general purpose sequencing data as well.
openaire   +2 more sources

Innovative technologies crowd the short-read sequencing market

Nature, 2023
openaire   +2 more sources

Comparison of Structural and Short Variants Detected by Linked-Read and Whole-Exome Sequencing in Multiple Myeloma

Cancers, 2021
Ashwini Kumar, Sadiksha Adhikari, Matti Kankainen   +2 more
exaly  

Optical genome mapping and revisiting short-read genome sequencing data reveal previously overlooked structural variants disrupting retinal disease−associated genes

Genetics in Medicine, 2023
Suzanne E de Bruijn, Marcel R Nelen
exaly  

Oxford Nanopore R10.4 long-read sequencing enables the generation of near-finished bacterial genomes from pure cultures and metagenomes without short-read or reference polishing

Nature Methods, 2022
Mantas Sereika, Rasmus H Kirkegaard, Søren M Karst   +2 more
exaly  

Finding the right fit: evaluation of short-read and long-read sequencing approaches to maximize the utility of clinical microbiome data

Microbial Genomics, 2022
Jeanette L Gehrig, Daniel M Portik, Eric Jackson   +2 more
exaly  

Direct Comparative Analysis of a Pharmacogenomics Panel with PacBio Hifi® Long-Read and Illumina Short-Read Sequencing

Journal of Personalized Medicine, 2023
David Barthelemy, Lea Payen
exaly  

Short‐ and long‐read metabarcoding of the eukaryotic rRNA operon: Evaluation of primers and comparison to shotgun metagenomics sequencing

Molecular Ecology Resources, 2022
Meike A C Latz, Vesna Grujcic, Sonia Brügel   +2 more
exaly  

Short and Long-Read Sequencing Survey of the Dynamic Transcriptomes of African Swine Fever Virus and the Host Cells

Frontiers in Genetics, 2020
Dora Tombácz, Zsolt Csabai, Norbert Moldovan   +2 more
exaly