Results 131 to 140 of about 8,462,031 (305)

SPHINX31 acts as a SRPK1 inhibitor targeting the ATR/DNA‐PKcs/CHK1 replicative checkpoint to inhibit cell growth in non‐small cell lung cancer

open access: yesMolecular Oncology, EarlyView.
The kinase SRPK1 directly interacts with the protein TOPBP1 and regulates the pre‐mRNA splicing of WIZ thereby contributing to the activation of the ATR/CHK1 replicative checkpoint in response to replicative stress. This allows cancer cells' genomic stability and survival.
Amani Shreim   +17 more
wiley   +1 more source

Research on an Ultra-Short-Term Wind Speed Prediction Method Based on Improved Combined Neural Networks [PDF]

open access: yes
Ultra-short-term wind speed prediction is the key to ensure the implementation effect of wind turbine pitch angle feedforward control, and has an important impact on improving the environmental adaptability of wind turbines.
SHAO Yixiang   +5 more
core   +1 more source

Targeting the EpCAM‐AXL axis to overcome drug resistance in lung cancer

open access: yesMolecular Oncology, EarlyView.
Lung cancer cells often evade therapy by hijacking signaling pathways. We reveal that cleaved EpCAM (sEpCAM) stabilizes the oncogenic protein AXL, driving NF‐κB and STAT3‐mediated chemoresistance. This EpCAM‐AXL axis identifies a high‐risk patient subset with poor prognosis.
Alexa Guerrero‐Alba   +5 more
wiley   +1 more source

Short-term prediction of coronary artery disease using serum metabolomic patterns. [PDF]

open access: yesAm Heart J Plus, 2022
Petrazzini BO   +12 more
europepmc   +1 more source

Short-Term Flood Prediction System

open access: yesGeoinformatica Polonica, 2014
AbstractThis paper describes a fully functional short-term flood prediction system. Its effect has been tested on watershed of Lubieńka river in Małopolska. To use this system it must have a data set also described in this paper. A modification of the system to adopt for predicting flash floods was described.
openaire   +1 more source

Characterization of therapeutic antibodies targeting lymphatic and vascular resistance factor for the treatment of hypervascularized and highly metastatic cancers

open access: yesMolecular Oncology, EarlyView.
LVRF (lymphatic and vascular resistance factor) is a VEGFA splice variant upregulated in response to anti‐angiogenic therapy that fosters tumor adaptation through enhanced vascularization, lymphangiogenesis, and metastatic dissemination. Targeting LVRF with fully human neutralizing antibodies disrupts these processes and limits resistant tumor growth ...
Marion David   +12 more
wiley   +1 more source

Hybrid LSTM Neural Network for Short-Term Traffic Flow Prediction

open access: yes, 2019
The existing short-term traffic flow prediction models fail to provide precise prediction results and consider the impact of different traffic conditions on the prediction results in an actual traffic network. To solve these problems, a hybrid Long Short&
Yuelei Xiao, Yang Yin
core   +1 more source

Guiding AlphaFold to predict how Munc13‐1 opens Syntaxin‐1

open access: yesFEBS Open Bio, EarlyView.
The syntaxin‐1 Habc‐domain (orange), linker (pink) and SNARE motif (yellow) form a closed conformation that binds to Munc18‐1 (violet) and is opened by the Munc13‐1 MUN domain (cyan) to form the SNARE complex that triggers neurotransmitter release.
Madhurima Chattopadhyay   +2 more
wiley   +1 more source

Financial Integration and the Market for Short-Term Paper [PDF]

open access: yes
The market for short-term paper continues to be somewhat fragmented and domestic in nature, owing primarily to different legal systems.
Doran, David
core  

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