Results 111 to 120 of about 1,772,398 (306)

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

FEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta, Hari Baskar Balasubramanian, Amir Pasokh, Marietta Zille   +3 more
wiley   +1 more source

Structure‐forward targeting of claudins with synthetic binders

FEBS Letters, EarlyView.
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley   +1 more source

Ultra‐Short‐Term Wind Power Prediction Based on Digital Twins

IET Renewable Power Generation
To address the issue of insufficient consideration of wind turbine physical characteristics and wind farm meteorological features in wind power forecasting, this paper proposes an ultra‐short‐term wind power prediction model based on digital twin ...
Aotian Yuan, Hengrui Ma, Changhua Yang, Hui Xiao, Bo Wang, David Wenzhong Gao, Qing La   +6 more
doaj   +1 more source

Machine Learning based Short-term Prediction of Air-conditioning Load through Smart Meter Analytics

, 2017
The present paper is focused on short-term prediction of air-conditioning (AC) load of residential buildings using the data obtained from a conventional smart meter.
M. Manivannan, Behzad Najafi, F. Rinaldi
semanticscholar   +1 more source

The microbiome in human skin aging

FEBS Letters, EarlyView.
Age‐related skin changes encompass the well‐known visible phenotypic alterations, together with microbiome dysbiosis and a series of molecular aging hallmarks. These hallmarks characterize not only a fully stablished aged phenotype but also the skin aging process itself.
Manuel Huerta Arana, Cornelia Wiegand, Omid Omrani, Mario Fabri   +3 more
wiley   +1 more source

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

Molecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang, Ayesha Alvero, Yi Qin, Mingjin Wang, Alexandra Fox, Yanfeng Li, Michael Millman, Amy Kemper, Gil Mor, Xian Shuang Liu, Michael Chopp, Zheng Gang Zhang, Yi Zhang   +12 more
wiley   +1 more source

Short-term prediction of on-street parking occupancy using multivariate variable based on deep learning

Journal of Traffic and Transportation Engineering (English ed. Online)
Short-term prediction of on-street parking occupancy is essential to the ITS system, which can guide drivers in finding vacant parking spaces. And the spatial dependencies and exogenous dependencies need to be considered simultaneously, which makes short-
Mengqi Lyu, Yanjie Ji, Chenchen Kuai, Shuichao Zhang   +3 more
doaj   +1 more source

Dengue in Myanmar: Spatiotemporal epidemiology, association with climate and short-term prediction. [PDF]

PLoS Negl Trop Dis, 2023
Zaw W, Lin Z, Ko Ko J, Rotejanaprasert C, Pantanilla N, Ebener S, Maude RJ.   +6 more
europepmc   +1 more source

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch, Isabel Vogel, Sina Nokodian, Johanna Moeller, Antonia Blechschmidt, Vicky Hecht, Vanessa Kuentzel, Katharina Thiedig, Melissa Schwab, Oliver Schilling, Holger Bronger, Marion Kiechle, Viktor Magdolen, Tobias Dreyer   +13 more
wiley   +1 more source

Short-Term Prediction of Multi-Energy Loads Based on Copula Correlation Analysis and Model Fusions. [PDF]

Entropy (Basel), 2023
Xie M, Lin S, Dong K, Zhang S.
europepmc   +1 more source