Results 111 to 120 of about 8,462,031 (305)
Molecular Oncology, EarlyView.The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka +9 more
wiley +1 more source
Predictions of short-term rates and the expectations hypothesis of the term structure of interest rates [PDF]
Despite its important role in monetary policy and finance, the expectations hypothesis (EH) of the term structure of interest rates has received virtually no empirical support.
Guidolin, Massimo, Thornton, Daniel L.
core
Long-Term Traffic Prediction Using Deep Learning Long Short-Term Memory
Traffic conditions are a key factor in our society, contributing to quality of life and the economy, as well as access to professional, educational, and health resources. This emphasizes the need for a reliable road network to facilitate traffic fluidity
Wael Khallouli +7 more
core +1 more source
Molecular Oncology, EarlyView.Breast cancer remains a major cause of cancer death in women, frequently developing endocrine therapy resistance. This study demonstrates that upregulated p21‐activated kinase 1 (PAK1) activity drives resistance to tamoxifen and long‐term estrogen deprivation in ER+ breast cancer models.
Luisa Schwarzmüller +10 more
wiley +1 more source
Molecular Oncology, EarlyView.Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq +8 more
wiley +1 more source
, 2019 Digital platforms are changing cities in many subtle and profound ways. The short-term rentals website Airbnb is just one prominent example of how new online intermediaries reshape urban practices and imaginaries, change social relationships, disrupt ...
Laura Lieto
core
Molecular Oncology, EarlyView.Detecting circulating tumor cells (CTCs) in blood before surgery may help predict outcomes in patients with head and neck squamous cell carcinoma (HNSCC). Here, we show when combined with tumor size and lymph node involvement from routine imaging, CTC status identifies high‐risk patients with poorer survival—offering a simple, minimally invasive tool ...
Susanne Flach +9 more
wiley +1 more source
Prediction of short-term clinical outcomes of CTS patients by baseline ultrasound results.
, 2016 Prediction of short-term clinical outcomes of CTS patients by baseline ultrasound results.
Rene Thonhofer (3135201) +16 more
core +1 more source
Ultra‐Short‐Term Wind Power Prediction Based on Digital Twins
IET Renewable Power GenerationTo address the issue of insufficient consideration of wind turbine physical characteristics and wind farm meteorological features in wind power forecasting, this paper proposes an ultra‐short‐term wind power prediction model based on digital twin ...
Aotian Yuan +6 more
doaj +1 more source
PANoptosis in the pathogenesis of myelodysplastic syndromes
Molecular Oncology, EarlyView.PANoptosis, a combination of three types of programmed cell death, is mediated by a large protein complex called a PANoptosome. In healthy bone marrow hematopoietic cells, PANoptosis is restricted by inhibitory signaling. In MDS, bone marrow cells become sensitive to the PANoptotic stimuli due to the aberrant inactivation of inhibitory signaling or ...
Rohit Thalla +4 more
wiley +1 more source