Results 121 to 130 of about 8,462,031 (305)

Somatostatin receptor 4 (SSTR4) is a tumor suppressor in cutaneous and head & neck squamous cell carcinomas

Molecular Oncology, EarlyView.
This study identifies somatostatin receptor 4 (Sstr4) as a critical tumor suppressor against skin and head/neck cancers (HNSCC, cSCC, and BCC). The loss of Sstr4 removes a check on cell growth, causing hyperactivation of the MAPK‐ERK signaling pathway (↑).
Ali Taqvi, Tuan Khang Huynh, Adway Kadam, Zahra Kardan, Yue Yan, Amina Jamal Laham, Sampath Kumar Loganathan   +6 more
wiley   +1 more source

Short-term prediction of on-street parking occupancy using multivariate variable based on deep learning

Journal of Traffic and Transportation Engineering (English ed. Online)
Short-term prediction of on-street parking occupancy is essential to the ITS system, which can guide drivers in finding vacant parking spaces. And the spatial dependencies and exogenous dependencies need to be considered simultaneously, which makes short-
Mengqi Lyu, Yanjie Ji, Chenchen Kuai, Shuichao Zhang   +3 more
doaj   +1 more source

Castration‐resistant prostate cancer cells are addicted to the high activity of cyclin‐dependent kinase 2

Molecular Oncology, EarlyView.
We show that emergence of castration‐resistant prostate (CRPC) is associated with significant upregulation of cyclins that positively regulate cyclin‐dependent kinase 2 (CDK2) and concomitant downregulation of CDK4 cyclins. This renders CRPC cells dependent on the high activity of CDK2, and CDK2 inhibitors synergistically sensitize CRPC cells to both ...
Joyeeta Chatterjee, Alessia Marin, Shivani Yalala, Harri M. Itkonen   +3 more
wiley   +1 more source

The VHL tumor suppressor at the crossroad of protein folding, aggregation, and cancer

Molecular Oncology, EarlyView.
Mutations, environmental stress, and chaperone dysfunction can destabilize pVHL, promoting its conversion from the native folded state into amyloid‐like assemblies. This transition may contribute to protein storage, cell dormancy, survival, and drug resistance.
Lara Abad, Silvio Carlo Ermanno Tosatto, Emanuela Leonardi   +2 more
wiley   +1 more source

Short Term Aircraft Trajectory Prediction

, 2009
Im Kontext mit Lotsenunterstützungssystemen soll mit einer “Short Term Aircraft Trajectory Prediction“ ausgehend vom aktuellen Flugzustand eine Vorausberechnung der zu erwartenden Flugzustände im 30 Sekunden Bereich erfolgen.
Stump, Raimar
core  

Lower Limb Kinematics Trajectory Prediction Using Long Short-Term Memory Neural Networks

, 2020
Lower Limb Kinematics Trajectory Prediction Using Long Short-Term Memory Neural ...
Daniel Lai (17963087), R Begg (13283700), A Zaroug (19814103), K Mudie (11660092)   +3 more
core  

p190A/ARHGAP35 and p190B/ARHGAP5 proteins in endometrial cancer: a novel cancer‐relevant paralog interplay

Molecular Oncology, EarlyView.
This study identifies ARHGAP5, in addition to the frequently mutated ARHGAP35, as significantly mutated in endometrial cancer. Mutations in both genes co‐occur and are associated with their correlated downregulation. Functional CRISPR studies show that both paralogs regulate similar pathways, including actin cytoskeleton organization.
Mathilde Pinault, Capucine Heraud, Mélissa Correia de Oliveira, Véronique Neaud, Valérie Valesco, Valérie Prouzet‐Mauleon, Béatrice Turcq, Jean‐William Dupuy, Anne‐Aurélie Raymond, Sabrina Croce, Frédéric Saltel, Valérie Lagrée, Violaine Moreau   +12 more
wiley   +1 more source

Combining meteorological and power information of station-measurement and model-prediction with the hybrid CNN-Transformer and CNN-BiLSTM for ultra-short-term photovoltaic power forecasting

International Journal of Electrical Power & Energy Systems
The photovoltaic (PV) industry is rapidly developing and plays a key role in the renewable energy sector. PV power is affected by meteorological factors, which are cyclical and stochastic.
Yuchen Dai, Yuanbing Wang, Yaodeng Chen, Junwen Wu, Jie Chao   +4 more
doaj   +1 more source

Dengue in Myanmar: Spatiotemporal epidemiology, association with climate and short-term prediction. [PDF]

PLoS Negl Trop Dis, 2023
Zaw W, Lin Z, Ko Ko J, Rotejanaprasert C, Pantanilla N, Ebener S, Maude RJ.   +6 more
europepmc   +1 more source

Unique circulating miRNAome signatures captured with distinct molecular states in Lynch syndrome and sporadic colorectal cancer

Molecular Oncology, EarlyView.
Circulating microRNA profiles distinguish nonmalignant Lynch syndrome from cancer‐associated Lynch syndrome, sporadic colorectal cancer, and healthy controls. Age‐stratified analysis reveals disease‐specific regulatory states, and a six‐miRNA panel shows concordant separation in an independent colorectal tissue cohort.
Ramadhani Salum Chambuso, Md Shohel Ul Islam, Rosa M Xicola, Raj Ramesar, Xavier Llor, Sinclair Steele   +5 more
wiley   +1 more source