Results 51 to 60 of about 334,674 (285)
The anticipated performance of calorimeter crystals in the environment expected after the planned High-Luminosity upgrade of the Large Hadron Collider (HL-LHC) at CERN has to be well understood, before informed decisions can be made on the need for ...
Dissertori, G. +7 more
core +2 more sources
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva +5 more
wiley +1 more source
Structural biology of ferritin nanocages
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley +1 more source
Deep shower interpretation of the cosmic ray events observed in excess of the Greisen-Zatsepin-Kuzmin energy [PDF]
We consider the possibility that the ultra-high-energy cosmic ray flux has a small component of exotic particles which create showers much deeper in the atmosphere than ordinary hadronic primaries.
A. M. Hillas +11 more
core +2 more sources
AAA+ protein unfoldases—the Moirai of the proteome
AAA+ unfoldases are essential molecular motors that power protein degradation and disaggregation. This review integrates recent cryo‐electron microscopy (cryo‐EM) structures and single‐molecule biophysical data to reconcile competing models of substrate translocation.
Stavros Azinas, Marta Carroni
wiley +1 more source
Evaluating Short-Wave Effects in Railway Track Using the Rail Surface Signal
Condition assessment and maintenance planning of railway infrastructure is a prerequisite for safe and reliable train operation. As the loads are constantly increasing, condition assessment of the track must also be further developed.
Markus Loidolt, Stefan Marschnig
doaj +1 more source
Nuclear emulsion measurements of the astronauts' radiation exposures on Skylab missions 2, 3, and 4 [PDF]
On the Skylab missions, Ilford G.5 and K.2 emulsions were flown as part of passive dosimeter packs carried by the astronauts on their wrists. Due to the long mission times, latent image fading and track crowing imposed limitations on a quantitative track
Schaefer, H. J., Sullivan, J. J.
core +2 more sources
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat +8 more
wiley +1 more source
A Novel Short-Range Prediction Model for Railway Track Irregularity
In recent years, with axle loads, train loads, transport volume, and travel speed constantly increasing and railway network steadily lengthening, shortcomings of current maintenance strategies are getting to be noticed from an economical and safety ...
Peng Xu +3 more
doaj +1 more source
Trigger efficiencies at BES III
Trigger efficiencies at BES III were determined for both the J/psi and psi' data taking of 2009. Both dedicated runs and physics datasets are used; efficiencies are presented for Bhabha-scattering events, generic hadronic decay events involving charged ...
Da-Peng Jin +12 more
core +1 more source

