Results 71 to 80 of about 334,674 (285)

Circulating tumor cell viability during and after radiotherapy mirrors treatment response in cancer patients

Molecular Oncology, EarlyView.
Radiotherapy (RT) response depends on the DNA repair capacity of tumor and host cells. We show that circulating tumor cell (CTC) counts and apoptosis rates before and after RT predict treatment response and outcome, which can be accessed via easily accessible liquid biopsy approaches. Created in BioRender. Wikman, H.
Yvonne Goy, Jana Löptien, Cornelia Coith, Afroditi Nanou, Katharina Hintelmann, Pinnschmidt Hans, Cordula Petersen, Klaus Pantel, Sabine Riethdorf, Kerstin Borgmann, Harriet Wikman   +10 more
wiley   +1 more source

A light‐triggered Time‐Resolved X‐ray Solution Scattering (TR‐XSS) workflow with application to protein conformational dynamics

FEBS Open Bio, EarlyView.
Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei, Fredrik Orädd, Konstantinos Magkakis, Magnus Andersson   +3 more
wiley   +1 more source

Postural myoadaptive disorders in short track athletes

Insight - Sports Science
Our article is the first to conduct a study of short track athletes in the Russian Federation, which revealed the presence of postural muscle changes in the back. The study used a neuro-orthopedic examination, original instruments and a questionnaire method.
Yuri Olegovich Novikov, Anna Sergeevna Yasinskaya, Sofya Marsovna Musina   +2 more
openaire   +1 more source

Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies

FEBS Open Bio, EarlyView.
We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli, Mohammad Nour Alsamsam, Ugnė Bagdonaitė, Van Truc Vu, Chun‐Jen Huang, Polina Kuzhir, Mindaugas Zaremba, Aurimas Kopūstas, Marijonas Tutkus   +8 more
wiley   +1 more source

Exon 7 splicing of ERα predicts poor prognosis and increases phenotypic heterogeneity in luminal a subtype breast cancer

FEBS Open Bio, EarlyView.
ERα splice variant ERα∆7 lacks the C‐terminus, and its expression may change phenotypes of breast cancers. Our results showed that ERα∆7 is found in the luminal A subtype, and elevated ERα∆7 levels are linked to improved cell survival with lower proliferation and migration.
Long Wai Tsui, Taobo Hu, Thomson Christian Husein, Wai Hei Shek, Bingrong Chen, Depeng Wang, Shu Wang, Weichuan Yu, Xiaodan Fan, Mengping Long, Toyotaka Ishibashi   +10 more
wiley   +1 more source

Search for \nu_\mu -> \nu_\tau oscillations in appearance mode in the OPERA experiment [PDF]

, 2011
The OPERA experiment in the underground Gran Sasso Laboratory (LNGS) has been designed to perform the first detection of neutrino oscillations in direct appearance mode in the muon neutrino to tau neutrino channel.
Kose, Umut
core   +2 more sources

Analysing the significance of small conformational changes and low occupancy states in serial crystallographic data

FEBS Open Bio, EarlyView.
This protocol paper outlines methods to establish the success of a time‐resolved serial crystallographic experiment, by means of statistical analysis of timepoint data in reciprocal space and models in real space. We show how to amplify the signal from excited states to visualise structural changes in successful experiments.
Jake Hill, Yelyzaveta Pulnova, Elke De Zitter, Helen M. Ginn, Briony A. Yorke   +4 more
wiley   +1 more source

Blood‐based proteomic profiling reveals context‐dependent changes in BCL2‐associated signaling during taxane therapy in breast cancer patients

FEBS Open Bio, EarlyView.
Chemotherapy side effects significantly impact cancer survivors' quality of life. Using protein levels in blood samples from breast cancer patients before and after 12 weeks of taxane treatment, we detected treatment‐dependent changes in calcium signaling and aging pathways associated with cancer recurrence.
Saira Munshani, Eiman Y. Ibrahim, Rozalyn L. Rodwin, Leah M. Ferrucci, Kim Blenman, Maryam Lustberg, Barbara E. Ehrlich   +6 more
wiley   +1 more source

Short-term prediction algorithm of air target track based on residual correction CNN-BiLSTM [PDF]

Zhihui kongzhi yu fangzhen
To solve the problem of low track prediction accuracy caused by the limitations of deep learning and the cumulative error generated by recursive prediction strategies, a short-term prediction algorithm for air target tracks based on residual correction ...
WANG Shuo, WU Nan, HUANG Jie, WANG Jiantao
doaj   +1 more source

A High Statistics Search for Electron-Neutrino --> Tau-Neutrino Oscillations

, 1998
We present new limits on nu_e to nu_tau and nu_e to nu_sterile oscillations by searching for electron neutrino dissappearance in the high-energy wide-band CCFR neutrino beam.
A. Bodek, A. O. Bazarko, A. Romosan, A. Romosan, B. Achkar, B. J. King, B. J. King, C. Arroyo, C. Athanassopolous, C. G. Arroyo, C. H. Albright, C. McNulty, D. A. Harris, D. Naples, E. G. Stern, F. J. Sciulli, G. Feldman, G. Ingelman, G. Zacek, H. Budd, H. Schellman, J. Conrad, J. H. Kim, J. Yu, K. S. McFarland, L. de Barbaro, M. H. Shaevitz, M. J. Lamm, M. Vakili, N. Ushida, O. Erriquez, P. de Barbaro, P. Spentzouris, P. Z. Quintas, R. A. Johnson, R. B. Drucker, R. H. Bernstein, R. M. Barnett, S. Jadach, S. R. Mishra, T. Bolton, T. Kinnel, U. K. Yang, W. C. Lefmann, W. G. Seligman, W. H. Smith, W. K. Sakumoto, W. K. Sakumoto, W. Marsh, Y. Fukada   +49 more
core   +1 more source