Results 61 to 70 of about 4,085,017 (238)

Until Sniffer Dogs Can Talk: CRIM-TRACK

, 2022
This image is a digitally drawn short comic highlighting the CRIM-TRACK sniffer, a device that utilises a colourimetric sensor system to detect illicit compounds by their vapour at sensitivity rivalling a sniffer dog, but with better discrimination. Both
Hardy, Iona, Iona Hardy (8394924)
core   +1 more source

Pharmacological chromatin remodeling enhances response to estrogen therapy in ER+ breast cancer

Molecular Oncology, EarlyView.
Estrogen therapy elicits clinical benefit in ~ 30% of patients with endocrine‐resistant estrogen receptor (ER)‐positive breast cancer. Based on findings that ER transcriptional activation underlies response to estrogen therapy, we tested the effects of epigenetic dysregulation via pharmacological inhibition of histone deacetylases (HDACi).
Anneka L. Johnson Thomas, Barbara Karakyriakou, Patricia C. Muskus, Alyssa M. Roberts, Justin Rendleman, Alexa Warren, Hanxu Lu, Kimberly A. Birmingham, Malone K. Friedman, Abigail E. Goen, Huijuan Yang, Owen M. Wilkins, Fred W. Kolling, Eugene Demidenko, Julie M. Jorns, Brock C. Christensen, Todd W. Miller   +16 more
wiley   +1 more source

Short-term prediction algorithm of air target track based on residual correction CNN-BiLSTM [PDF]

Zhihui kongzhi yu fangzhen
To solve the problem of low track prediction accuracy caused by the limitations of deep learning and the cumulative error generated by recursive prediction strategies, a short-term prediction algorithm for air target tracks based on residual correction ...
WANG Shuo, WU Nan, HUANG Jie, WANG Jiantao
doaj   +1 more source

Spatial biology in cancer epigenetics

Molecular Oncology, EarlyView.
Spatial epigenomics combines molecular profiling with tissue architecture to reveal how gene regulation is organized within intact tissues. In cancer, these technologies uncover the mechanisms driving tumor heterogeneity and microenvironmental interactions, opening new opportunities for biomarker discovery and precision medicine.
Eva Crespo‐García, Manel Esteller
wiley   +1 more source

Track Irregularity Time Series Analysis and Trend Forecasting

Discrete Dynamics in Nature and Society, 2012
The combination of linear and nonlinear methods is widely used in the prediction of time series data. This paper analyzes track irregularity time series data by using gray incidence degree models and methods of data transformation, trying to find the ...
Jia Chaolong, Xu Weixiang, Wang Futian, Wang Hanning   +3 more
doaj   +1 more source

Somatostatin receptor 4 (SSTR4) is a tumor suppressor in cutaneous and head & neck squamous cell carcinomas

Molecular Oncology, EarlyView.
This study identifies somatostatin receptor 4 (Sstr4) as a critical tumor suppressor against skin and head/neck cancers (HNSCC, cSCC, and BCC). The loss of Sstr4 removes a check on cell growth, causing hyperactivation of the MAPK‐ERK signaling pathway (↑).
Ali Taqvi, Tuan Khang Huynh, Adway Kadam, Zahra Kardan, Yue Yan, Amina Jamal Laham, Sampath Kumar Loganathan   +6 more
wiley   +1 more source

Reduction of Corrugation by Semi-Active Track [PDF]

, 2004
This article discusses possibilities for application of semi-active actuators to reduce rail and wheel wear. A simple model of a vehicle/track interaction is presented. The model is extended with a model of semi-active actuators. The feedback control law
Preumont, A., Valasek, M., Vaculin, O.
core  

Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies

FEBS Open Bio, EarlyView.
We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli, Mohammad Nour Alsamsam, Ugnė Bagdonaitė, Van Truc Vu, Chun‐Jen Huang, Polina Kuzhir, Mindaugas Zaremba, Aurimas Kopūstas, Marijonas Tutkus   +8 more
wiley   +1 more source

CS Track Investigating Citizen Science brochure

, 2022
CS Track, a research project funded by the European Commission, aims at broadening knowledge about citizen science by applying data analysis to publicly available information from the web and collecting complementary data through questionnaires and ...
CS Track
core   +1 more source

From energy provision to protein synthesis: Tunnelling nanotubes as mediators of intercellular metabolic cooperation in cancer

FEBS Open Bio, EarlyView.
The cytoskeleton‐mediated transport of mitochondria via tunnelling nanotubes restores respiration, increases ATP production, rescues cells from apoptosis, activates the AKT/mTOR signalling pathway, promotes cell migration and invasiveness, contributes to cancer progression and treatment resistance.
Stanislava Martínková, Jan Trnka
wiley   +1 more source