Results 61 to 70 of about 358,334 (318)
Re-tubularization of highly-ischemic anti-mesenteric border (ReHAB)
Journal of Pediatric Surgery Case Reports, 2021 Complex gastroschisis and other etiologies of intestinal compromise present a difficult medical and surgical challenge in the neonatal and pediatric population.
Joseph J. Lopez, Richard J. Hendrickson
doaj +1 more source
The use of FK-506 for small intestine llotransplantation: Inhibition of acute rejection and prevention of fatal graft-versus-host disease [PDF]
, 1990 Small intestine allotransplantation in humans is not yet feasible due to the failure of the current methods of immunosuppression. FK-506, a powerful new immunosuppressive agent that is synergistic with cyclosporine, allows long-term survival of ...
Banner, B +7 more
core +1 more source
Molecular Oncology, EarlyView.Methods to improve antibody–drug conjugate (ADC) treatment durability in cancer therapy are needed. We utilized ADCs and immune‐stimulating antibody conjugates (ISACs), which are made from two non‐competitive antibodies, to enhance the entry of toxic payloads into cancer cells and deliver immunostimulatory agents into immune cells.
Tiexin Wang +3 more
wiley +1 more source
Adolescent reproductive health and awareness of HIV among rural high school students, North Western Ethiopia. [PDF]
, 2004 Ethiopia is faced with an increasing problem from HIV infection, and the vulnerability of adolescents is a key concern. There is little information on the knowledge, attitudes and practices of this age group with respect to HIV, sexually transmitted ...
Banat, Ibrahim M +3 more
core +2 more sources
Molecular Oncology, EarlyView.Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee +8 more
wiley +1 more source
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
Congenital short bowel syndrome: a rare cause of neonatal intestinal obstruction
Journal of International Medical Research, 2020 Congenital short bowel syndrome (CSBS) is an uncommon gastrointestinal disorder in which an unclear aetiology causes considerable intrauterine reduction in small bowel length.
Mostafa Zain +3 more
doaj +1 more source
Molecular Oncology, EarlyView.Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley +5 more
wiley +1 more source
ジョウミャク エイヨウ ノ サポート オ フヨウ トスル タンチョウ ショウコウグン ノ イチセイジンレイ [PDF]
, 2010 We report a case of survival in the absence of intravenous nutritional support in an adult patient with short bowel syndrome, despite the very short length of the small and large intestine.
尾形 貴史 +8 more
core +1 more source
Exploring the genetics of irritable bowel syndrome: A GWA study in the general population and replication in multinational case-control cohorts [PDF]
, 2014 OBJECTIVE: IBS shows genetic predisposition, but adequately powered gene-hunting efforts have been scarce so far. We sought to identify true IBS genetic risk factors by means of genome-wide association (GWA) and independent replication studies.
Agreus, Lars +43 more
core +1 more source