Results 81 to 90 of about 190,792 (295)

Gut Microbiota‐Derived Anandamide Mediates the Therapeutic Effects of Urolithin A on Alcohol‐Induced Cognitive and Social Dysfunction via CB1R‐DRD2‐RAP1 Signaling Axis

open access: yesAdvanced Science, EarlyView.
This study reveals that Urolithin A (UA) counteracts alcohol‐induced cognitive and social dysfunction (AICSD) via a gut microbiome‐dependent mechanism. UA‐enriched Bacteroids sartorii and Parabacteroids distasonis elevate anandamide (AEA), which activates the CB1R‐DRD2‐Rap1 signaling cascade to drive synaptic repair and reduce neuroinflammation ...
Hongbo Zhang   +9 more
wiley   +1 more source

Effect of teduglutide, a glucagon-like peptide-2 analog, in eosinophilic enterocolitis: a case report

open access: yesFrontiers in Pediatrics
We successfully treated a 4-year-old girl with short bowel syndrome and eosinophilic enterocolitis with teduglutide, a glucagon-like peptide-2 analog.
Shoko Ogawa   +7 more
doaj   +1 more source

Short bowel syndrome: A review of management options

open access: yesThe Saudi Journal of Gastroenterology, 2011
Extensive resection of the intestinal tract frequently results in inadequate digestion and/or absorption of nutrients, a condition known as short bowel syndrome (SBS).
Prasad Seetharam, Gabriel Rodrigues
doaj   +1 more source

Biomechanical Force Prediction for Lengthening of Small Intestine during Distraction Enterogenesis

open access: yesBioengineering, 2020
Distraction enterogenesis has been extensively studied as a potential treatment for short bowel syndrome, which is the most common form of intestinal failure. Different strategies including parenteral nutrition and surgical lengthening to manage patients
Hadi S. Hosseini, James C. Y. Dunn
doaj   +1 more source

Cadaveric small bowel and small bowel-liver transplantation in humans [PDF]

open access: yes, 1992
Five patients had complete cadaveric small bowel transplants under FK506 immunosuppression, one as an isolated graft and the other 4 in continuity with a liver. Three were children and two were adults.
Abu-Elmagd, K   +13 more
core   +1 more source

A Novel Function of Nonadecanoic Acid in Regulating Glucose Homeostasis

open access: yesAdvanced Science, EarlyView.
This study identifies the odd‐chain fatty acid C19:0 as an endogenous ligand of GPR120 that promotes glucose homeostasis via Gαq signaling. In obesity, elevated palmitic acid suppresses endogenous C19:0 production through a miRNA–PPARα–HACL1 pathway, offering a promising direction for understanding the role of OCFAs in human health.
Yanting Hou   +14 more
wiley   +1 more source

An International Urogynecological Association (IUGA)/International Continence Society (ICS) joint report on the terminology for the conservative and nonpharmacological management of female pelvic floor dysfunction [PDF]

open access: yes, 2016
There has been an increasing need for the terminology on the conservative management of female pelvic floor dysfunction to be collated in a clinically based consensus report.This Report combines the input of members and elected nominees of the ...
Abramov, Yoram   +14 more
core   +3 more sources

Pathogenic Role of FGFR3 Autoantibodies in Small Fiber Neuropathy

open access: yesAdvanced Science, EarlyView.
Autoantibodies against fibroblast growth factor receptor 3 (FGFR3) are identified as pathogenic drivers of pain in small fiber neuropathy. By binding to sensory neurons in dorsal root ganglia, FGFR3 autoantibodies activate MAPK signaling and induce hyperexcitability and mechanical hypersensitivity, establishing FGFR3 autoantibodies as a therapeutic ...
Lyuba Y. Salih   +12 more
wiley   +1 more source

Multidisciplinary Management in Pediatric Ultrashort Bowel Syndrome

open access: yesJournal of Multidisciplinary Healthcare, 2020
Christina Belza,1 Paul W Wales1,2 1Group for Improvement of Intestinal Function and Treatment (GIFT), The Hospital for Sick Children, University of Toronto, Toronto, Canada; 2Division of General and Thoracic Surgery, The Hospital for Sick Children ...
Belza C, Wales PW
doaj  

Osmolality of Elemental and Semi-Elemental Formulas Supplemented with Nonprotein Energy Supplements [PDF]

open access: yes, 2008
Elemental and semi-elemental formulas are used to feed infants with short bowel syndrome, who may not be able to tolerate feeds of more than 310 mOsm kg(-1).
Pereira-da-Silva, L   +3 more
core   +1 more source

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