Results 221 to 230 of about 55,448 (270)

Nanozymes for Advanced Hemoglobin‐Based Oxygen Carriers: Applications in Blood Substitution, Wound Healing, Antitumor Therapy, and Beyond

Advanced Science, EarlyView.
This review explores how hemoglobin‐based oxygen carriers (HBOCs) combined with nanozymes create multifunctional materials that deliver oxygen while maintaining redox homeostasis. Beyond artificial blood substitutes, these constructs enable wound healing with light‐triggered oxygen release, cancer therapy through enhanced oxygenation and reactive ...
Despoina Douka, Ana María Pablo‐Sainz‐Ezquerra, Eva Jakljevič, Niki Ktena, Leticia Hosta‐Rigau   +4 more
wiley   +1 more source

Crystal Facet‐Polysaccharide Matching in CFS‐P Nanocrystals Drives Fungal Uptake, Vacuole Destruction, and Selective Antifungal Activity

Advanced Science, EarlyView.
Facet‐engineered PVP‐capped CuFeSe2 nanocrystals exhibit potent, selective antifungal activity by strongly binding cell‐wall mannan, enabling vacuolar entry and organelle disruption. High‐index facets show superior mannan affinity, validated by theoretical calculations and experiments. CFS‐P induces vacuolar cavitation, mitochondrial abnormalities, and
Zhaohui Wang, Xiaojin Deng, Xujuan Huang, Yuhang Pan, Yao Qin, Lu Zhang, Le Xu, Tianyi Qin, Deteng Zhang, Yi Ma, Yalong Wang   +10 more
wiley   +1 more source

Endogenous Engineering Reprograms Extracellular Vesicles for Enhanced Therapeutic Function

Advanced Science, EarlyView.
This review explains how Extracellular vesicles‐producing cells can be endogenously engineered to load therapeutic proteins and nucleic acids. We summarize physiological and genetic strategies that harness native sorting pathways for selective cargo loading.
Jinghui Wang, Wenxuan Zhao, Xiaoming Hu, Yishu Wang, Peidong Yang, Diwei Zheng, Yugang Wang, Guanghui Ma, Min Shi, Wei Wei, Shuang Wang   +10 more
wiley   +1 more source

Anticipatory Corticosteroid Administration to Asymptomatic Women with a Short Cervix

American Journal of Perinatology, 2017
Objective A short cervix is an important risk factor for spontaneous preterm birth. There is substantial evidence that antenatal exposure to corticosteroids significantly benefits infants that are born when delivery occurs between 24 and 34 weeks' gestation and after 48 hours but within 7 days of their administration.
Douglas S, Richards, Luchin F, Wong, M Sean, Esplin, Dave S, Collingridge   +3 more
openaire   +3 more sources

Progesterone and the Risk of Preterm Birth among Women with a Short Cervix

New England Journal of Medicine, 2007
Previous randomized trials have shown that progesterone administration in women who previously delivered prematurely reduces the risk of recurrent premature delivery. Asymptomatic women found at midgestation to have a short cervix are at greatly increased risk for spontaneous early preterm delivery, and it is unknown whether progesterone reduces this ...
Fonseca, E B, Celik, E, Parra, M, Singh, M, Nicolaides, K H, Thornton, S, Alfirevic, Z, Smith, G, Radhakrishnan, P, Khoury, O, Divianathan, L, Kaul, A, Rao, A, Kuppusamy, R, Molina, F, Turan, S, Gajewska, K, Palanappian, V, Paramasivam, G, Atzei, A, Poggi, S, Vafaie, H, Hagan, P, Coward, H, Milovanovic, Z, Nikolopoulou, D, Tsolakidis, F, Rencoret, G, Pedraza, D, Valdes, E, Valadares, S, Damiao, R, Skentou, H   +32 more
openaire   +4 more sources

Is midtrimester short cervix a sign of intraamniotic inflammation?

American Journal of Obstetrics and Gynecology, 2009
We sought to determine the relationship between the degree of cervical shortening and intraamniotic inflammation in patients presenting with a midtrimester short cervix.Amniocentesis was performed on singleton pregnancies between 16-24 weeks' gestation with a sonographic cervical length (CL) 1500 pg/mL, CL of 5 mm had an 86% sensitivity, 85 ...
Daniel G, Kiefer, Sean M, Keeler, Orion A, Rust, Christopher P, Wayock, Anthony M, Vintzileos, Nazeeh, Hanna   +5 more
openaire   +4 more sources

A sonographic short cervix as the only clinical manifestation of intra-amniotic infection

Journal of Perinatal Medicine, 2006
Objective: A sonographically short cervix is a powerful predictor of spontaneous preterm delivery. However, the etiology and optimal management of a patient with a short cervix in the mid-trimester of pregnancy remain uncertain. Microbial invasion of the
Sonia Hassan, Roberto Romero, Jimmy Espinoza   +2 more
exaly   +2 more sources

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Short Cervix in a Patient With Twin Gestation

Obstetrics & Gynecology, 2017
A 28-year-old woman, gravida 1 para 0, with twin gestation presents for routine anatomic survey at 20 weeks of gestation without any complaints. On transabdominal ultrasonography, the ultrasonographer notes concern for cervical funneling and proceeds to perform a transvaginal ultrasonogram, which reveals a short cervix of 18 mm.
Manisha, Gandhi, Nathan S, Fox
openaire   +4 more sources

Does the presence of a funnel increase the risk of adverse perinatal outcome in a patient with a short cervix?

American Journal of Obstetrics and Gynecology, 2005
OBJECTIVE: This study was undertaken to determine whether the presence of a dilated internal os (funneling or beaking) alters the outcome of patients with a short cervix documented by transvaginal ultrasound in the second trimester. STUDY DESIGN: Between
Orion A Rust, Robert O Atlas, William E Roberts   +2 more
exaly   +2 more sources