Results 51 to 60 of about 55,448 (270)

Long-term indomethacin therapy and cervical stabilization in dichorionic twin pregnancies

The Journal of Maternal-Fetal & Neonatal Medicine
Objective To evaluate the effect of long-term indomethacin therapy (LIT) in stabilizing cervical length in dichorionic-diamniotic (DCDA) twin pregnancies with a short cervix.Methods This retrospective cohort study included 54 dichorionic-diamniotic twin ...
Mevlut Bucak, Karl Seif, Katherine Goetzinger, Sifa Turan, Christopher Harman, Ozhan Turan   +5 more
doaj   +1 more source

The impact of cervical conization size with subsequent cervical length changes on preterm birth rates in asymptomatic singleton pregnancies

Scientific Reports, 2021
The study aimed to explore the impact of cervical conization size (CCS) with subsequent cervical length (USCL) changes on preterm birth (PTB) rates in asymptomatic singleton pregnancies as compared to pregnancy outcomes in healthy women with an intact ...
Sergei V. Firichenko, Michael Stark, Ospan A. Mynbaev   +2 more
doaj   +1 more source

Serum vitamin (OH-25) D levels in cases (with a short cervix) and controls (with a normal cervix).

, 2014
Serum vitamin (OH-25) D levels in cases (with a short cervix) and controls (with a normal cervix).
Danielle S. Abbott (606403), Rachel M. Tribe (292018), Paul T. Seed (292014), Manju Chandiramani (292013), Andrew H. Shennan (292017), Evonne C. Chin-Smith (606404)   +5 more
core   +1 more source

Positron emission tomography/computerised tomography imaging in detecting and managing recurrent cervical cancer: systematic review of evidence, elicitation of subjective probabilities and economic modelling. [PDF]

, 2013
© Queen’s Printer and Controller of HMSO 2013. This work was produced by Meads et al. under the terms of a commissioning contract issued by the Secretary of State for Health.
Meads, C., P Barton, P Guest, C Davenport, Borowiack, E., Khan, K., Thangaratinam, S, Martin-Hirsch, P., Sundar, S.; id_orcid, Zapalska, A., Guest, Peter, Thangaratinam, S.; id_orcid, Barton, P., C Meads, T Roberts, Kowalska, M., P Auguste, Małysiak, S, M Kowalska, A Zapalska, Khan, K, S Sundar, S Thangaratinam, Meads, C, Roberts, T., Davenport, C, Sundar, S, Barton, P, Auguste, P., Kowalska, M, Guest, P, P Martin-Hirsch, Martin-Hirsch, P, Davenport, C.; id_orcid, S Małysiak, Zapalska, A, Roberts, T, E Borowiack, Auguste, P, Małysiak, S., K Khan, Borowiack, E   +41 more
core   +1 more source

Interventions to prevent preterm delivery in women with short cervix before fetoscopic laser surgery for twin–twin transfusion syndrome

, 2022
OBJECTIVE: Preoperative short cervical length (CL) remains a major risk factor for preterm birth after laser surgery for twin-twin transfusion syndrome (TTTS), but the optimal intervention to prolong pregnancy remains elusive. The objective of this study
J. Miller, H. Galan, A. Baschat, S. Blackwell, E. P. Bergh, Peiro, J L, Thom, E, Papanna, R, A. Johnson, Baschat, A, Macpherson, C, Galan, H, C. Brock, C. Pedroza, R. Papanna, C. Buskmiller, J. Fisher, N. Behrendt, Habli, M, E. Thom, M. Habli, Pedroza, C, Blackwell, S, Snowise, S, J. L. Peiro, Brock, C, Fisher, J, Miller, J, Buskmiller, C, C. Macpherson, Behrendt, N, Bergh, E P, S. Snowise, Johnson, A   +33 more
core   +1 more source

Cell‐cycle‐specific lesion evolution rather than inhibition of double‐strand‐break repair underpins cisplatin radiosensitization

Molecular Oncology, EarlyView.
We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu, Xixi Lin, Emil Mladenov, Veronika Mladenova, Jürgen Thomale, Ali Sak, Yao Wang, Yunxuan Deng, Eleni Gkika, Martin Stuschke, George Iliakis   +10 more
wiley   +1 more source

Is the Relationship between Short Interpregnancy Interval and Preterm Birth Related to a Short Cervix?

, 2017
Objective Our objective was to determine if the relationship between interpregnancy interval (IPI) and preterm delivery was related to cervical shortening.
S. Govindappagari, C. Gyamfi-Bannerman, A. Merriam, N. Zork   +3 more
core   +1 more source

Adaptor protein CIN85 potentiates the motility of osteosarcoma cells via the Akt/mTOR and MMP2‐COL3A1 axis

Molecular Oncology, EarlyView.
CIN85 is highly expressed in osteosarcoma, particularly in metastatic lesions. Its overexpression increases cell migration and Matrigel invasion, while silencing CIN85 suppresses these behaviors. Transcriptome analysis shows that CIN85 regulates MMP2, COL3A1, and Akt/mTOR signaling. Targeting these pathways reverses CIN85‐induced motility, highlighting
Iryna Horak, Iva Staniczková Zambo, Matěj Přikryl, Peter Múdry, Danica Zapletalová, Jarmila Navrátilová, Jiří Navrátil, Jan Šmarda, Liudmyla Drobot, Petr Beneš, Lucia Knopfová   +10 more
wiley   +1 more source

Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining

Molecular Oncology, EarlyView.
IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis, Jack V. Mills, Wojciech Niedzwiedz, Valentine M. Macaulay   +3 more
wiley   +1 more source

947 Recurrence risk of short cervix in women with history of short cervix and term delivery [PDF]

American Journal of Obstetrics and Gynecology, 2021
Samsiya Ona, Shai Bejerano, Cheng Chen, Melanie Polin, Brittany Arditi, Joy-Sarah Vink, Jaclyn L. Coletta, Cynthia Gyamfi-Bannerman, Amy Turitz   +8 more
openaire   +1 more source