Results 141 to 150 of about 1,244,170 (347)

Non-Gaussian Current Fluctuations in a Short Diffusive Conductor [PDF]

, 2018
Edouard Pinsolle, Samuel Houle, Christian Lupien, Bertrand Reulet   +3 more
openalex   +1 more source

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

Molecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat, Aslihan Kucuk, Omer Erdogan, Samed Ozer, Bensu Kozan, Tugba Cuceli, Erkan Gumus, Evrim Cevik, Ozge Cevik   +8 more
wiley   +1 more source

Climate Fluctuations and Growing Sensitivity of Grape Production in Abruzzo (Central Italy) over the Past Sixty Years

Geographies
The sensitivity of the agricultural production system to short- and long-term climate variations significantly affects the availability and prices of food resources, raising relevant issues of sustainability and food security.
Vincenzo Guerriero, Anna Rita Scorzini, Bruno Di Lena, Mario Di Bacco, Marco Tallini   +4 more
doaj   +1 more source

The short-term mortality fluctuation data series, monitoring mortality shocks across time and space [PDF]

, 2021
Dmitri A. Jdanov, Ainhoa Alústiza Galarza, Vladimir M. Shkolnikov, Domantas Jasilionis, László Németh, David A. Leon, Carl Boe, Magali Barbiéri   +7 more
openalex   +1 more source

Correlation of the differential expression of PIK3R1 and its spliced variant, p55α, in pan‐cancer

Molecular Oncology, EarlyView.
PIK3R1 undergoes alternative splicing to generate the isoforms, p85α and p55α. By combining large patient datasets with laboratory experiments, we show that PIK3R1 spliced variants shape cancer behavior. While tumors lose the protective p85α isoform, p55α is overexpressed, changes linked to poorer survival and more pronounced in African American ...
Ishita Gupta, Yang Song, Madeleine Ndahayo, Anirudh Saxena, Theresa Guo, Dylan Z. Kelley, Jessica Gore, Andrew Hennigan, Alexa Anderson, John C. Papadimitriou, Daria A. Gaykalova   +10 more
wiley   +1 more source

Sudden Infant Death Syndrome: Abnormalities in Short Term Fluctuations in Heart Rate and Respiratory Activity [PDF]

, 1984
David Gordon, Richard J. Cohen, Dorothy H. Kelly, S. Akselrod, Daniel C. Shannon, Barney Kenet, F. Andrew Ubel, O. Dale Williams   +7 more
openalex   +1 more source

A Model of Foreign Exchange Rate Indetermination [PDF]

Economic agents undertake actions to protect themselves from the short-run impact of foreign exchange rate fluctuations: Nominal goods prices are set in consumers' currencies, and firms hedge foreign exchange risk.
Charles Engel
core  

Basroparib inhibits YAP‐driven cancers by stabilizing angiomotin

Molecular Oncology, EarlyView.
Basroparib, a selective tankyrase inhibitor, suppresses Wnt signaling and attenuates YAP‐driven oncogenic programs by stabilizing angiomotin. It promotes AMOT–YAP complex formation, enforces cytoplasmic YAP sequestration, inhibits YAP/TEAD transcription, and sensitizes YAP‐active cancers, including KRAS‐mutant colorectal cancer, to MEK inhibition.
Young‐Ju Kwon, Dong Young Kim, Yuna Kim, Uk‐Il Kim, Jae‐Sung Kim   +4 more
wiley   +1 more source

NEW INSIGHT INTO SHORT-WAVELENGTH SOLAR WIND FLUCTUATIONS FROM VLASOV THEORY [PDF]

, 2012
F. Sahraoui, G. Belmont, M. L. Goldstein
openalex   +1 more source

Understanding Short-Term and Long-Term Price Fluctuations of Main Staple Food Commodities in Aceh Province, Indonesia: An ARDL Investigation

, 2023
Hadi Arisyah Putra, Ade Habya Fijay, Suriani Suriani, Chenny Seftarita, Edi Saputra Ringga, Heri Wintara, Oka Fadliansah   +6 more
openalex   +2 more sources