Results 251 to 260 of about 3,914,190 (307)

Yeast Gcn2 retains activity following humanization of its auto‐phosphorylation region

FEBS Open Bio, EarlyView.
Using Saccharomyces cerevisiae as a model to study Gcn2 activation and regulation is limited by the lack of antibodies detecting phosphorylated Gcn2. To overcome this, we engineered Gcn2‐HsC, a yeast Gcn2 variant recognizable by commercial anti‐human phospho‐GCN2 antibodies.
Reuben A. Anderson, Anja H. Schiemann, Evelyn Sattlegger   +2 more
wiley   +1 more source

Beyond Systolic Blood Pressure Variability: Additional Considerations for Blood Pressure Monitoring in Acute Ischemic Stroke. [PDF]

J Clin Hypertens (Greenwich)
Demirkıran A, Aydın C, Engin M.
europepmc   +1 more source

Malformin A1–mediated cytotoxicity in ovarian cancer cells occurs through pyroptosis and autophagy

FEBS Open Bio, EarlyView.
This study investigated the effects of the natural compound Malformin A1 (MA1) on the cytoskeleton that regulates cell proliferation and migration. Disruption of the cytoskeleton can impair these processes and promote cancer cell death. MA1 disrupted cytoskeletal organization, induced DNA damage, inflammation, activated autophagy, and pyroptosis ...
Nada Abdullah Hassan, Ikram A. Burney, Shika Hanif Malgundkar, Siva Ramamoorthy, Ressin Varghese, Mohamed A. Al‐Kindi, Hamad Al Riyami, Shadia Al Bahlani, Sergey Dobretsov, Syed Imran Hassan, Benjamin K. Tsang, Yahya Tamimi   +11 more
wiley   +1 more source

Temporal Dynamics of Influenza-Associated Anxiety Symptom Linguistic Markers on Weibo (2023-2024): Observational Study. [PDF]

JMIR Infodemiology
Ou Y, Bruijn GJ, Schulz PJ.
europepmc   +1 more source

Ionomycin suppresses cancer cell growth by disrupting mitochondrial transcription

FEBS Open Bio, EarlyView.
In this study, we identify a new function for the selective Ca2+ ionophore, ionomycin, as an inhibitor of mitochondrial transcription. Both total and nascent RNA analyses revealed that ionomycin treatment reduces the transcription of mitochondrial genes.
Lishen Wang, Mingqiang Deng, Dongmei He, Diqin Lai, Dongjun Liu, Dengyong Zhu, Zhenhua Zhang, Peng Tang, Chuanman Zhou, Menghui Yin, Xichen Bao   +10 more
wiley   +1 more source

Short-term blood pressure variability assessed by ambulatory blood pressure monitoring as a predictor of subclinical target organ damage. [PDF]

Front Cardiovasc Med
Hong Y, Xie S, Jiang H.
europepmc   +1 more source

Exploring the influence of lactoferrin on wound healing and related signaling pathways: a systematic review

FEBS Open Bio, EarlyView.
Lactoferrin promotes wound healing by activating MAPK, PI3K/Akt, and extracellular matrix pathways, enhancing fibroblast remodeling, proliferation, and re‐epithelialization. These mechanisms highlight its therapeutic potential in inflammation control, tissue repair, and remodeling.
Morgana Lüdtke Azevedo, Kátia Cristiane Hall, Matheus dos Santos Fernandez, Geovanna Peter Corrêa, Rafael Guerra Lund   +4 more
wiley   +1 more source

From Static Structures to Molecular Dynamics: Emerging Directions in X-Ray and Electron Materials Characterization. [PDF]

Materials (Basel)
Sasaki D, Mio K, Sasaki YC.
europepmc   +1 more source

Stability of movement by a multi-element system: drifts and random walk within and orthogonal to the uncontrolled manifold during multi-finger force production. [PDF]

Exp Brain Res
De SD, Latash ML.
europepmc   +1 more source

The Relationship Between Physical Activity and Mobile Phone Addiction Among Adolescents: A Cross-Lagged Study. [PDF]

Behav Sci (Basel)
Wang H, Dai Y.
europepmc   +1 more source