Results 111 to 120 of about 6,347,071 (258)
Relations professionnelles entres bibliothèques et petits éditeurs indépendants (Les) [PDF]
L’enquête menée par le MOTif part d’un constat a priori simple : les petits éditeurs souhaitent être plus présents dans les rayons des bibliothèques, tandis que les bibliothécaires peuvent regretter de ne pas connaître ces mêmes éditeurs et par ...
Le MOTif
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Spatial biology in cancer epigenetics
Molecular Oncology, EarlyView.Spatial epigenomics combines molecular profiling with tissue architecture to reveal how gene regulation is organized within intact tissues. In cancer, these technologies uncover the mechanisms driving tumor heterogeneity and microenvironmental interactions, opening new opportunities for biomarker discovery and precision medicine.
Eva Crespo‐García, Manel Esteller
wiley +1 more source
BMC Bioinformatics, 2008 Background The structure of many eukaryotic cell regulatory proteins is highly modular. They are assembled from globular domains, segments of natively disordered polypeptides and short linear motifs.
López Rodrigo +4 more
doaj +1 more source
Molecular Oncology, EarlyView.This study identifies somatostatin receptor 4 (Sstr4) as a critical tumor suppressor against skin and head/neck cancers (HNSCC, cSCC, and BCC). The loss of Sstr4 removes a check on cell growth, causing hyperactivation of the MAPK‐ERK signaling pathway (↑).
Ali Taqvi +6 more
wiley +1 more source
Molecular Oncology, EarlyView.We show that emergence of castration‐resistant prostate (CRPC) is associated with significant upregulation of cyclins that positively regulate cyclin‐dependent kinase 2 (CDK2) and concomitant downregulation of CDK4 cyclins. This renders CRPC cells dependent on the high activity of CDK2, and CDK2 inhibitors synergistically sensitize CRPC cells to both ...
Joyeeta Chatterjee +3 more
wiley +1 more source
Molecular Oncology, EarlyView.Arginine methylation can be viewed as a persistence‐prone post‐translational modification regulated by a network of PRMTs. Competitive and compensatory interactions among PRMTs can redistribute methylation across substrate pools shaped by sequence, structural, spatial, and environmental layers, reinforcing RNA‐processing, chromatin, and signaling ...
So Hyun Kwon, Ji Min Lee
wiley +1 more source
Molecules, 2017 Linear, dimeric, tetrameric, and cyclic peptides derived from lactoferricin B–containing non-natural amino acids and the RWQWR motif were synthesized, purified, and characterized using RP-HPLC, MALDI-TOF mass spectrometry, and circular dichroism.
Nataly De Jesús Huertas Méndez +7 more
doaj +1 more source
Molecular mimicry of host short linear motif-mediated interactions utilised by viruses for entry. [PDF]
Mol Biol Rep, 2023 Goswami S, Samanta D, Duraivelan K.
europepmc +1 more source
Penç Motif in Anatolian Seljuk Art
Türk sanatının kökenleri yüzyıllar öncesine dayanır. Sağlam ve derin temeller üzerine kurulan sanatımız, farklı medeniyetlerin kültürüyle yoğrulmuş, dünya sanat tarihine yön vermiştir.
Özsoy, Hamide Nur
core +1 more source
The VHL tumor suppressor at the crossroad of protein folding, aggregation, and cancer
Molecular Oncology, EarlyView.Mutations, environmental stress, and chaperone dysfunction can destabilize pVHL, promoting its conversion from the native folded state into amyloid‐like assemblies. This transition may contribute to protein storage, cell dormancy, survival, and drug resistance.
Lara Abad +2 more
wiley +1 more source