Results 71 to 80 of about 11,813 (259)

Design and analysis strategies for robust microbiome ageing research

open access: yesFEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik   +5 more
wiley   +1 more source

Photometry and Multipolar Magnetic Field Modeling of Polars: BY Camelopardalis and FL Ceti

open access: yesActa Polytechnica CTU Proceedings, 2015
We present new broad band optical photometry of two magnetic cataclysmic variable stars, the asynchronous polar BY Camelopardalis and the short period polar FL Ceti.
P. A. Mason   +5 more
doaj   +1 more source

An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes

open access: yesFEBS Letters, EarlyView.
GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg   +14 more
wiley   +1 more source

Transient Processes in a Binary System with a White Dwarf

open access: yesActa Polytechnica CTU Proceedings, 2015
Using the results of 3D gas dynamic numerical simulations we propose a mechanism that can explain the quiescent multihumped shape of light curves of WZ Sge short-period cataclysmic variable stars.
D. A. Kononov   +3 more
doaj   +1 more source

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch   +13 more
wiley   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

open access: yesMolecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric   +10 more
wiley   +1 more source

Searching for GEMS: Discovery of the Nearby Post-common-envelope Binary System TIC-460388167

open access: yesThe Astrophysical Journal
Short-period white dwarf + main-sequence binaries are post-common-envelope binaries (PCEBs) that have survived a common envelope phase. Such systems, if detached and eclipsing, enable precise measurements of the constituent stars, providing a unique ...
Alexandra Boone   +13 more
doaj   +1 more source

The color changes of certain variable stars of short period.

open access: yesThe Astrophysical Journal, 1919
"Reprinted from the Astrophysical journal, vol. L, no. 3, October, 1919." ; "Private edition, distributed by the University of Chicago libraries, Chicago, Illinois." ; Thesis (Ph. D.)--University of Chicago, 1914. ; Mode of access: Internet.
openaire   +2 more sources

Variable Stars in Leo A: RR Lyrae Stars, Short-Period Cepheids, and Implications for Stellar Content

open access: yesThe Astronomical Journal, 2002
46 pages, 12 figures Accepted by ...
Dolphin, AE   +8 more
openaire   +3 more sources

Stimulator of interferon genes agonist augmented antitumor immunity of osimertinib in Egfr‐mutated lung cancer

open access: yesMolecular Oncology, EarlyView.
Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura   +19 more
wiley   +1 more source

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