Results 111 to 120 of about 20,149 (199)

Electrocardiographic Predictors of Major Adverse Cardiovascular Events in Women With Suspected Ischemia and no Obstructive Coronary Artery Disease: Results of the Women's Ischemia Syndrome Evaluation

Annals of Noninvasive Electrocardiology, Volume 31, Issue 3, May 2026.
A cohort of 481 female participants of the Women's Ischemia Syndrome Evaluation (WISE) Original study clinically phenotyped as having suspect ischemia with no obstructive coronary arteries (INOCA) were evaluated for baseline ECG and clinical predictors of time to incident major adverse cardiac events (MACE).
Jennifer R. Dungan, Yasmeen K. Taha, Qinglin Pei, Michael T. Weaver, Michael J. Tavormina, Steven E. Reis, Eileen M. Handberg, C. Noel Bairey Merz, Carl J. Pepine   +8 more
wiley   +1 more source

Alternative Lead ECG Placements

Annals of Noninvasive Electrocardiology, Volume 31, Issue 3, May 2026.
Alternative ECG lead placements can improve diagnostic yield when the standard 12‐lead ECG is suboptimal or infeasible. This review summarizes practical, scenario‐driven modifications (right‐sided, posterior, seated/prone, Lewis, Fontaine, torso‐based, and monitoring configurations) to better detect ischemia, right ventricular disease/ARVD, and ...
José Luis Morales‐Arteaga, Amin Meghdadi, Derek Wu, Abdullah Bhuiyan, Nicole Langleben, Cengiz Burak, Emily Wilson, Ashley Pellerito, David Aristizábal, Keanu Razzaghi, Juan Maria Farina, Shyla Gupta, Adrian Baranchuk   +12 more
wiley   +1 more source

Population‐Based Study Found Low Risk of Misdiagnosing Long QT Syndrome as Breath‐Holding Spells in Swedish Children

Acta Paediatrica, Volume 115, Issue 5, Page 1116-1125, May 2026.
ABSTRACT Aim An electrocardiogram is commonly recommended in breath‐holding spell management, mainly to rule out long QT syndrome. This retrospective study investigated the risk of long QT syndrome being misdiagnosed as breath‐holding spells in a paediatric population in southern Sweden.
Sanna Hellström Schmidt, Ida Jeremiasen, Erik A. Eklund, Cornelis Jan Pronk   +3 more
wiley   +1 more source

Structural interplay of KV7.1 and KCNE1 is essential for normal repolarization and is compromised in short QT syndrome 2 (KV7.1-A287T)

HeartRhythm Case Reports, 2016
Ina Rothenberg, PhD, Ilaria Piccini, PhD, Eva Wrobel, PhD, Birgit Stallmeyer, PhD, Jovanca Müller, MD, Boris Greber, PhD, Nathalie Strutz-Seebohm, PhD, Eric Schulze-Bahr, MD, Nicole Schmitt, PhD, Guiscard Seebohm, PhD   +9 more
doaj   +1 more source

Opening closed inward rectifier potassium channel doors

British Journal of Pharmacology, Volume 183, Issue 10, Page 2197-2218, May 2026.
Inwardly rectifying potassium (KIR) channels are essential regulators of membrane potential in excitable and non‐excitable tissues. Although KIR channels exhibit a biophysical preference for potassium influx due to voltage‐dependent block of outward current by polyamines and Mg2+, under physiological conditions, they predominantly mediate K+ efflux ...
Anna Stary‐Weinzinger, Fabian Kaiser, Marcel A. G. van der Heyden, Saïd Bendahhou   +3 more
wiley   +1 more source

Utilizing human induced pluripotent stem cells to study atrial arrhythmias in the short QT syndrome.

J Mol Cell Cardiol, 2023
Shiti A, Arbil G, Shaheen N, Huber I, Setter N, Gepstein L.   +5 more
europepmc   +1 more source

Machine Learning‐Based Prediction of Drug‐Induced QTc Changes in a Large Finnish Biobank Cohort

Clinical and Translational Science, Volume 19, Issue 5, May 2026.
ABSTRACT Prolongation of the QT interval is a known precursor to serious arrhythmias and sudden cardiac death, often triggered by medication use. Current medication risk evaluation platforms rely on literature‐based synthesis and may lag behind real‐world developments.
Ville Langén, Aleksi Winstén, Konsta Teppo, Timo Pohjonen, Jari Laukkanen, Arto Mannermaa, Teemu J. Niiranen, Joonatan Palmu   +7 more
wiley   +1 more source

A Scoping Review of Non‐Opioid Therapeutics for Opioid Withdrawal: Translational Relevance to Neonatal Opioid Withdrawal Syndrome (NOWS) Research

Clinical and Translational Science, Volume 19, Issue 5, May 2026.
ABSTRACT In the wake of the ongoing opioid epidemic, the incidence of neonatal opioid withdrawal syndrome (NOWS) has surged. While the short‐term effects of NOWS are well‐characterized, long‐term physiological and molecular consequences remain unclear.
Sara L. Mills‐Huffnagle, Oliver M. Lowden, Rhea E. Sullivan, Taryn E. McFadden, Jennifer E. Nyland   +4 more
wiley   +1 more source

Deciphering the pathogenic role of a variant with uncertain significance for short QT and Brugada syndromes using gene‐edited human‐induced pluripotent stem cell‐derived cardiomyocytes and preclinical drug screening

Clinical and Translational Medicine, 2021
Ibrahim El‐Battrawy, Huan Lan, Lukas Cyganek, Lasse Maywald, Rujia Zhong, Feng Zhang, Qiang Xu, Jihyun Lee, Eliane Duperrex, Andreas Hierlemann, Ardan M. Saguner, Firat Duru, Boldizsar Kovacs, Mengying Huang, Zhenxing Liao, Sebastian Albers, Jonas Müller, Hendrik Dinkel, Lena Rose, Alyssa Hohn, Zhen Yang, Lin Qiao, Yingrui Li, Siegfried Lang, Mandy Kleinsorge, Andreas Mügge, Assem Aweimer, Xuehui Fan, Sebastian Diecke, Ibrahim Akin, Guang Li, Xiaobo Zhou   +31 more
doaj   +1 more source

Mechano-electrical feedback in transgenic rabbit models of long QT syndrome Type 2 and short QT syndrome Type 1. [PDF]

Europace
Alerni N, Buonocunto M, Nimani S, Louradour J, Barbieri M, Giammarino L, Matas L, Lumens J, Delhaas T, Koren G, Lopez R, Zehender M, Brunner M, Ördög B, Heijman J, Odening KE.   +15 more
europepmc   +1 more source