Results 1 to 10 of about 9,035 (197)
Korean Journal of Pediatrics, 2014 Channelopathies are a heterogeneous group of disorders resulting from the dysfunction of ion channels located in the membranes of all cells and many cellular organelles.
June-Bum Kim
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Intellectual Disability and Potassium Channelopathies: A Systematic Review
Frontiers in Genetics, 2020 Intellectual disability (ID) manifests prior to adulthood as severe limitations to intellectual function and adaptive behavior. The role of potassium channelopathies in ID is poorly understood.
Miriam Kessi, Baiyu Chen, Jing Peng
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Journal of Cardiovascular Development and Disease, 2016 Cardiovascular diseases and, among them, channelopathies and cardiomyopathies are a major cause of death worldwide. The molecular and genetic defects underlying these cardiac disorders are complex, leading to a large range of structural and functional ...
Ouarda Taghli-Lamallem +2 more
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Journal of the American Heart Association, 2019 Background Brugada syndrome and long‐QT syndrome may account for at least one third of unexplained sudden cardiac deaths. Dental care in patients with cardiac channelopathies is challenging because of the potential risk of life‐threatening events.
Ana Carolina Guimarães Oliveira +2 more
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Polyunsaturated Phospholipids Increase Cell Resilience to Mechanical Constraints
Cells, 2021 If polyunsaturated fatty acids (PUFAs) are generally accepted to be good for health, the mechanisms of their bona fide benefits still remain elusive. Membrane phospholipids (PLs) of the cardiovascular system and skeletal muscles are particularly enriched
Linette Kadri +7 more
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Inherited arrhythmia syndrome predisposing to sudden cardiac death [PDF]
The Korean Journal of Internal Medicine, 2021 Inherited arrhythmia (IA) is one of the main causes of sudden cardiac death (SCD) in young people, and is reported to be a more prevalent cause of SCD in Asia than in Western countries.
Yun Gi Kim +3 more
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Approach to Neurological Channelopathies and Neurometabolic Disorders in Newborns
Life, 2021 Ion channel disorders (channelopathies) can affect any organ system in newborns before 2 months of life, including the skeletal muscle and central nervous system. Channelopathies in newborns can manifest as seizure disorders, which is a critical issue as
Inn-Chi Lee
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Fayixue Zazhi, 2022 Hereditary cardiac disease accounts for a large proportion of sudden cardiac death （SCD） in young adults. Hereditary cardiac disease can be divided into hereditary structural heart disease and channelopathies.
DONG Yi-ming +3 more
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Frontiers in Cardiovascular Medicine, 2023 Cardiovascular diseases are associated with several morbidities and are the most common cause of worldwide disease-related fatalities. Studies show that treatment and outcome-related differences for cardiovascular diseases disproportionately affect ...
Sahil Zaveri +9 more
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Vulnerability of Human Cerebellar Neurons to Degeneration in Ataxia-Causing Channelopathies
Frontiers in Systems Neuroscience, 2022 Mutations in ion channel genes underlie a number of human neurological diseases. Historically, human mutations in ion channel genes, the so-called channelopathies, have been identified to cause episodic disorders.
David D. Bushart, Vikram G. Shakkottai
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