Results 1 to 10 of about 16,999 (238)
Intellectual Disability and Potassium Channelopathies: A Systematic Review
Frontiers in Genetics, 2020 Intellectual disability (ID) manifests prior to adulthood as severe limitations to intellectual function and adaptive behavior. The role of potassium channelopathies in ID is poorly understood.
Miriam Kessi +17 more
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Approach to Neurological Channelopathies and Neurometabolic Disorders in Newborns
Life, 2021 Ion channel disorders (channelopathies) can affect any organ system in newborns before 2 months of life, including the skeletal muscle and central nervous system. Channelopathies in newborns can manifest as seizure disorders, which is a critical issue as
Inn-Chi Lee
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Journal of Cardiovascular Development and Disease, 2016 Cardiovascular diseases and, among them, channelopathies and cardiomyopathies are a major cause of death worldwide. The molecular and genetic defects underlying these cardiac disorders are complex, leading to a large range of structural and functional ...
Ouarda Taghli-Lamallem +2 more
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Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2019 Background Brugada syndrome and long‐QT syndrome may account for at least one third of unexplained sudden cardiac deaths. Dental care in patients with cardiac channelopathies is challenging because of the potential risk of life‐threatening events.
Ana Carolina Guimarães Oliveira +15 more
doaj +3 more sources
Episodic Disorders: Channelopathies and Beyond [PDF]
Annual Review of Physiology, 2015 Louis J Ptáček
exaly +3 more sources
Pleiotropic Effects of the NSAID Fenamates on Chloride Channels: Opportunity for Ion Channelopathies? [PDF]
Pharmacology Research & PerspectivesChloride channels are involved in many cellular processes, including cell volume regulation, modulation of cell excitability, and electrolyte and water secretion.
Paola Laghetti +4 more
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What Should a Clinical Cardiologist Know About Cardiogenetics? [PDF]
Journal of the American Heart Association: Cardiovascular and Cerebrovascular DiseaseInherited cardiovascular diseases are becoming increasingly prominent in clinical practice, significantly impacting diagnosis, risk assessment, and family screening strategies. Progress in genetic testing has broadened access to cardiogenetic evaluations,
Andrea Faggiano +15 more
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Voltage-Gated Sodium Channel Dysfunction in Epilepsy: Zebrafish Models for Therapeutics [PDF]
BiomedicinesVoltage-gated sodium channels (VGSCs) play pivotal roles in cellular function, particularly in the regulation of electrical signaling. Structural defects in these channels cause deleterious effects in a myriad of cell types, leading to various diseases ...
Angela Gyamfi +4 more
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Polyunsaturated Phospholipids Increase Cell Resilience to Mechanical Constraints
Cells, 2021 If polyunsaturated fatty acids (PUFAs) are generally accepted to be good for health, the mechanisms of their bona fide benefits still remain elusive. Membrane phospholipids (PLs) of the cardiovascular system and skeletal muscles are particularly enriched
Linette Kadri +7 more
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Inherited arrhythmia syndrome predisposing to sudden cardiac death [PDF]
The Korean Journal of Internal Medicine, 2021 Inherited arrhythmia (IA) is one of the main causes of sudden cardiac death (SCD) in young people, and is reported to be a more prevalent cause of SCD in Asia than in Western countries.
Yun Gi Kim +3 more
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