Results 151 to 160 of about 283,388 (253)

One is not enough: On the effects of reference genome for the mapping and subsequent analyses of short-reads. [PDF]

PLoS Comput Biol, 2021
Valiente-Mullor C, Beamud B, Ansari I, Francés-Cuesta C, García-González N, Mejía L, Ruiz-Hueso P, González-Candelas F.   +7 more
europepmc   +1 more source

Genetic dissection of human ABCE1 in yeast reveals separable requirements for ribosome recycling and suppression of aberrant reinitiation

FEBS Open Bio, EarlyView.
Human ABCE1 cannot functionally replace its yeast ortholog. Yeast–human chimera analysis identified NBD1 as a major interspecies barrier. Genetic screening yielded hABCE1 revertants that rescue yeast viability but fail to suppress aberrant translation reinitiation in the 3′ UTR.
Eriko Nakata, Yuxin Li, Kei Endo, Koichi Ito   +3 more
wiley   +1 more source

Comprehensive detection of structural variations in long and short reads dataset of French cattle. [PDF]

Sci Rep
Naji MM, Klopp C, Eché C, Di Franco A, Birbes C, Marcuzzo C, Suin A, Iampietro C, Kuchly C, Vernette C, Fritz S, Grohs C, Faraut T, Gaspin C, Milan D, Donnadieu C, Boichard D, Sanchez MP, Boussaha M.   +18 more
europepmc   +1 more source

Evaluating the accuracy of Listeria monocytogenes assemblies from quasimetagenomic samples using long and short reads. [PDF]

BMC Genomics, 2021
Commichaux S, Javkar K, Ramachandran P, Nagarajan N, Bertrand D, Chen Y, Reed E, Gonzalez-Escalona N, Strain E, Rand H, Pop M, Ottesen A.   +11 more
europepmc   +1 more source

IGF2 knockout reduces but does not abolish osteosarcoma growth in vitro and in vivo

FEBS Open Bio, EarlyView.
To test whether endogenous IGF2 promotes osteosarcoma growth, IGF2 was knocked out in Saos2 cells via CRISPR‐Cas9. KO cells showed reduced proliferation in vitro, and knockout xenografts in mice reached only ~25% of wild‐type tumor volume. Insulin‐like growth factor 2 (IGF2) is implicated in osteosarcoma, but direct functional evidence of its role is ...
Shun Yao, Marco Archetti
wiley   +1 more source

Testing the limits of short-reads metagenomic classifications programs in wastewater treating microbial communities. [PDF]

Sci Rep
Di Gloria L, Casbarra L, Lotti T, Ramazzotti M.   +3 more
europepmc   +1 more source

Type I interferons modulate autophagy to shape gemcitabine response in pancreatic cancer cells

FEBS Open Bio, EarlyView.
Type I interferons differentially modulate autophagy and the response of pancreatic cancer cells to gemcitabine. IFNα2b stimulates autophagic flux and protects cells from gemcitabine‐induced cell death, contributing to chemoresistance. In contrast, IFNβ1a inhibits autophagosome formation and enhances gemcitabine‐induced cell death, resulting in ...
Lucy E. Bonilla, Martín M. Ledesma, Santiago A. Behr, Matías A. Pibuel, María L. Palanek, Daniel H. Grasso, Maria N. Garcia, Juan Garona, Silvina L. Lompardía, Elida Álvarez, Daniela L. Papademetrio   +10 more
wiley   +1 more source

Optimal spliced alignments of short sequence reads

BMC Bioinformatics, 2008
Rätsch Gunnar, Schneeberger Korbinian, Ossowski Stephan, De Bona Fabio   +3 more
doaj   +1 more source

Construction of edit-distance graphs for large sets of short reads through minimizer-bucketing. [PDF]

Bioinform Adv
Ping P, Li J.
europepmc   +1 more source

Making the Most of Its Short Reads: A Bioinformatics Workflow for Analysing the Short-Read-Only Data of Leishmania orientalis (Formerly Named Leishmania siamensis) Isolate PCM2 in Thailand. [PDF]

Biology (Basel), 2022
Anuntasomboon P, Siripattanapipong S, Unajak S, Choowongkomon K, Burchmore R, Leelayoova S, Mungthin M, E-Kobon T.   +7 more
europepmc   +1 more source