Results 141 to 150 of about 6,463,650 (307)

Supply Chain Systems Architecture and Engineering Design: Green-field Supply Chain Integration [PDF]

open access: yes, 2015
This paper developed a new theory for supply chain architecture, and engineering design that enables integration of the business and supply chain strategies.
Petar Radanliev (16670205)   +2 more
core  

Characterization of therapeutic antibodies targeting lymphatic and vascular resistance factor for the treatment of hypervascularized and highly metastatic cancers

open access: yesMolecular Oncology, EarlyView.
LVRF (lymphatic and vascular resistance factor) is a VEGFA splice variant upregulated in response to anti‐angiogenic therapy that fosters tumor adaptation through enhanced vascularization, lymphangiogenesis, and metastatic dissemination. Targeting LVRF with fully human neutralizing antibodies disrupts these processes and limits resistant tumor growth ...
Marion David   +12 more
wiley   +1 more source

Transforming food systems in Semarang City, Indonesia: A short food supply chain model

open access: yesOpen Agriculture
Industrialized agro-food supply systems often negatively impact health, social relationships, and the environment. Short food supply chains (SFSCs) have emerged as a sustainable alternative, improving farmers’ livelihoods and reconnecting producers with ...
Widianarko Budi   +3 more
doaj   +1 more source

Overcoming platinum resistance by the disulfiram metabolite CuET in novel preclinical models of human carcinomas

open access: yesMolecular Oncology, EarlyView.
Cisplatin‐resistant cancer cells survive DNA‐damaging platinum‐based treatment yet remain sensitive to CuET‐induced proteotoxic stress. The distinct mechanism of action allows CuET to overcome and eliminate cisplatin‐resistant tumour cells, unless highly expressed metallothioneins (MTs) interfere with CuET, thereby highlighting MT levels as candidate ...
Stefanos Arampatzis   +20 more
wiley   +1 more source

Modeling regulatory impacts on medical device supply chains

open access: yes, 2018
Thesis: M. Eng. in Supply Chain Management, Massachusetts Institute of Technology, Supply Chain Management Program, 2018.Cataloged from PDF version of thesis.Includes bibliographical references (page 27).Changing regulatory requirements continues to be ...
Medina, Melissa (Melissa M.)
core  

We are What We Eat: Impact of Food from Short Supply Chain on Metabolic Syndrome. [PDF]

open access: yesJ Clin Med, 2019
Santulli G   +10 more
europepmc   +1 more source

Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies

open access: yesFEBS Open Bio, EarlyView.
We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli   +8 more
wiley   +1 more source

Integrating Healthcare Processes Through Supply Chain Principles

open access: yes, 2023
Healthcare supply chain has increasingly attracted the attention of scholars, researchers, government officials, and clinicians as one of the primary strategies in their efforts to reduce healthcare costs while improving quality.
Altabsh, Mariam
core  

Contributions to digital supply chain : design of short and local supply chains and decentralized planning

open access: yes, 2013
Le concept de chaîne logistique numérique regroupe l'ensemble des modèles, méthodes et outils qui permettent de planifier les décisions sur des prototypes numériques de chaîne logistique. Dans ce travail de thèse, nous proposons deux contributions à la chaîne logistique numérique.
openaire   +1 more source

Aquaporin‐3 and aquaporin‐5 impact the development of pancreatic ductal adenocarcinoma spheroids

open access: yesFEBS Open Bio, EarlyView.
Schematic representation of the role of aquaporin‐3 (AQP3) and aquaporin‐5 (AQP5) in pancreatic ductal adenocarcinoma (PDAC). Both proteins are upregulated in PDAC and are associated with tumor progression and metastatic potential. Silencing AQP3 or AQP5 in PDAC spheroids results in decreased diameter, area, and overall growth, underscoring their key ...
Catarina Pimpão   +3 more
wiley   +1 more source

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