Results 191 to 200 of about 651,047 (310)

Cyclic azapeptide CD36 ligand attenuates cardiac injury and reduces long‐chain fatty acid accumulation after myocardial ischemia–reperfusion in mice

FEBS Open Bio, EarlyView.
In a murine model of myocardial ischemia and reperfusion (MI/R), the CD36 azapeptide ligand MPE‐298 reduces cardiac injury and transiently lowers left ventricular long‐chain fatty acids (LCFAs) accumulation 3 h after reperfusion, accompanied by a decrease of oxidative stress and inflammation‐associated genes' expression in the heart and adipose tissue.
Jade Gauvin, Naghme Radmannia, David N. Huynh, Liliane Ménard, Caroline Daneault, Maïté Veilleux, Ahsanullah Ahsanullah, André C. Carpentier, William D. Lubell, Matthieu Ruiz, Huy Ong, Sylvie Marleau, Simon‐Pierre Gravel   +12 more
wiley   +1 more source

SUPPLY CHAINS FACING ATYPICAL DEMAND: OPTIMAL OPERATIONAL POLICIES AND BENEFITS UNDER INFORMATION SHARING

Demand patterns for products with seasonality and or short life-cycles do not follow a clear discernible pattern (to allow predictive time-series modeling of demand) for individual sales events or seasons due to such factors as considerable demand ...
Baruah, Pundarikaksha
core  

Exploring consumers’ attitude towards purchasing in short food supply chains

, 2015
This work investigates consumers’ attitudes that influence the intention to buy food in Short Food Supply Chains (SFSCs), instead of conventional market chains.
Finco A, Giampietri E., DEL GIUDICE, TERESA, Finco, Adele, Giampietri, Elisa   +4 more
core  

Application of the LightGBM algorithm in cross-border supply chain risk management: prediction and mitigation strategy development. [PDF]

Sci Rep
Xi D, Nie V, Li W.
europepmc   +1 more source

Aquaporin‐3 and aquaporin‐5 impact the development of pancreatic ductal adenocarcinoma spheroids

FEBS Open Bio, EarlyView.
Schematic representation of the role of aquaporin‐3 (AQP3) and aquaporin‐5 (AQP5) in pancreatic ductal adenocarcinoma (PDAC). Both proteins are upregulated in PDAC and are associated with tumor progression and metastatic potential. Silencing AQP3 or AQP5 in PDAC spheroids results in decreased diameter, area, and overall growth, underscoring their key ...
Catarina Pimpão, Diogo M. Engrácia, Graça Soveral, Filipa Mendes   +3 more
wiley   +1 more source

From supply to strategy: leveraging central medical stores experiences and information for health system strengthening. [PDF]

J Pharm Policy Pract
Tarrafeta-Sayas MB, Rerat C, Pilon S, Rakotonarivo MV, Koukpemedji LD, Yapo S, Duncan R, Hodjo D, Baki LS, Minoungou A, Ravinetto R.   +10 more
europepmc   +1 more source

Cutaneous Melanoma Drives Metabolic Changes in the Aged Bone Marrow Immune Microenvironment

Aging and Cancer, EarlyView.
Melanoma, the deadliest form of skin cancer, increasingly affects older adults. Our study reveals that melanoma induces changes in iron and lipid levels in the bone marrow, impacting immune cell populations and increasing susceptibility to ferroptosis.
Alexis E. Carey, Murilo Ramos Rocha, Cheyenne Palm, Vania Wang, Denys Balandin, Ethan Black, Kevin Y. Zhang, Fan Huang, Daniel J. Zabransky, Yash Chhabra, Mareike Peters, Gabriel Ghiaur, Ashani Weeraratna   +12 more
wiley   +1 more source

β-Casein Polymorphism as a Potential Evolutionary Trade-Off: The Rise of A1 Under Intensive Selection and Its Implications for Gastrointestinal Tolerance and Agroecological Resilience. [PDF]

Vet Sci
Tóth AJ, Kusza S, Sudár G, Kunszabó A, Battay M, Süth M, Bittsánszky A.   +6 more
europepmc   +1 more source

Long‐Term Follow‐Up of Chemotherapy‐Associated Biological Aging in Women With Early Breast Cancer

Aging and Cancer, EarlyView.
Women threated with adjuvant chemotherapy for early breast cancer have sustained long‐term increase in p16INK4a,, a robust marker of cell senescence, suggesting a chemotherapy‐associated age acceleration. p16INK4a as well as other biomarkers may identify patients at greatest risk for senescence‐related diseases of aging.
Hyman B. Muss, Alexis C. Wardell, Allison M. Deal, Kirsten A. Nyrop, Allison Ross, Yara G. Abdou, Jeffrey D. Aldrich, Lisa A. Cary, E. Claire Dees, Katherine E. Reeder‐Hayes, Emily M. Ray, Natalia Mitin, Denis Tsygankov   +12 more
wiley   +1 more source

Unpacking the problem-the hidden waste in neurointerventional procedures: quantifying packaging waste in neurointerventional supply chains. [PDF]

J Neurointerv Surg
Pfaff JAR, Schober M, Seethaler C, Oellerer A, Scheiber B, Liedtke IL.   +5 more
europepmc   +1 more source