Results 51 to 60 of about 656,034 (277)

Modeling the shortening history of a fault tip fold using structural and geomorphic records of deformation [PDF]

open access: yes, 2007
We present a methodology to derive the growth history of a fault tip fold above a basal detachment. Our approach is based on modeling the stratigraphic and geomorphic records of deformation, as well as the finite structure of the fold constrained from ...
Avouac, Jean-Philippe   +2 more
core   +3 more sources

Conserved structural motifs in PAS, LOV, and CRY proteins regulate circadian rhythms and are therapeutic targets

open access: yesFEBS Letters, EarlyView.
Cryptochrome and PAS/LOV proteins play intricate roles in circadian clocks where they act as both sensors and mediators of protein–protein interactions. Their ubiquitous presence in signaling networks has positioned them as targets for small‐molecule therapeutics. This review provides a structural introduction to these protein families.
Eric D. Brinckman   +2 more
wiley   +1 more source

How to shorten scientific manuscripts

open access: yesEcology and Evolution
Many journals have strict word limits, and authors therefore spend considerable time shortening manuscripts. Here, we provide pointers for efficiently doing so while retaining key content.
Ayco J. M. Tack   +2 more
doaj   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Shortened Regenerating Codes

open access: yesIEEE Transactions on Information Theory, 2019
11 ...
openaire   +2 more sources

Overview of molecular signatures of senescence and associated resources: pros and cons

open access: yesFEBS Open Bio, EarlyView.
Cells can enter a stress response state termed cellular senescence that is involved in various diseases and aging. Detecting these cells is challenging due to the lack of universal biomarkers. This review presents the current state of senescence identification, from biomarkers to molecular signatures, compares tools and approaches, and highlights ...
Orestis A. Ntintas   +6 more
wiley   +1 more source

The Oligocene Reifnitz tonalite (Austria) and its host rocks: implications for Cretaceous and Oligocene–Neogene tectonics of the south-eastern Eastern Alps

open access: yesGeologica Carpathica, 2018
In the south-eastern Eastern Alps, the Reifnitz tonalite intruded into the Austroalpine metamorphic basement of the Wörthersee half-window exposed north of the Sarmatian–Pliocene flexural Klagenfurt basin.
Neubauer Franz   +5 more
doaj   +1 more source

Quantification of three-dimensional folding using fluvial terraces: A case study from the Mushi anticline, northern margin of the Chinese Pamir

open access: yes, 2013
Fold deformation in three dimensions involves shortening, uplift, and lateral growth. Fluvial terraces represent strain markers that have been widely applied to constrain a fold's shortening and uplift.
Burbank, Douglas W.   +4 more
core   +1 more source

Leukocyte telomere shortening in Huntington's disease [PDF]

open access: yes, 2019
Huntington's disease (HD) is an autosomal dominant neurodegenerative disease caused by an expanded CAG repeat. Though symptom onset commonly occurs at midlife and inversely correlates with the CAG repeat expansion, age at clinical onset and progression ...
Corbo, Rm.   +5 more
core   +1 more source

TMC4 localizes to multiple taste cell types in the mouse taste papillae

open access: yesFEBS Open Bio, EarlyView.
Transmembrane channel‐like 4 (TMC4), a voltage‐dependent chloride channel, plays a critical role in amiloride‐insensitive salty taste transduction. TMC4 is broadly expressed in all mature taste cell types, suggesting a possible involvement of multiple cell types in this pathway.
Momo Murata   +6 more
wiley   +1 more source

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