Results 41 to 50 of about 106,975 (303)

Chronic Stress Promotes Gastric Cancer Metastasis by Inducing Microbiota‐Associated Kynurenine Accumulation and Macrophage Remodeling

Advanced Science, EarlyView.
Chronic stress reshapes the gut microbiota and enriches Lactobacillus reuteri, promoting microbiota‐associated kynurenine accumulation through altered tryptophan metabolism. Kynurenine drives immunosuppressive remodeling of tumor‐associated macrophages through TNFR2–C/EBPβ signaling, thereby enhancing gastric cancer dissemination.
Sicheng Zhao, Zhiyuan Song, Jingcheng Zhang, Jiaheng Lou, Shuo Zhang, Boqiang Liu, Yunhai Wei, Fengmei Qiu, Tao Jiang, Guangji Zhang   +9 more
wiley   +1 more source

An Unbiased Geometry‐Resolved Membrane Platform for Proteome‐Scale Discovery of Membrane Curvature Sensors

Advanced Science, EarlyView.
A novel geometry‐resolved membrane platform provides a seamlessly integrated pipeline for studying curvature‐sensing proteins. By linking shotgun proteomics with quantitative imaging, this approach enables both the unbiased discovery and rigorous validation of novel sensors across the entire curvature range—positive, negative, and zero.
Takumi Komikawa, Rikuto Kawakami, Kunanon Chattrairat, Tatsuya Niwa, Taiga Ajiri, Takao Yasui, Masayoshi Tanaka   +6 more
wiley   +1 more source

Sex‐ and Time‐Resolved Physiological and Gut Ecosystem Responses to a Food‐Grade Microbiome‐Targeted Intervention in Collegiate Endurance Athletes

Advanced Science, EarlyView.
In collegiate endurance athletes, a 6‐week randomized CPYE intervention yielded time‐ and sex‐dependent shifts in field‐based cardiorespiratory, metabolic, and redox indices, accompanied by changes in gut multi‐omics profiles. An exploratory extension during intensified training generates hypotheses warranting future validation.
Meng Zhang, Le Ge, Kaiyang Liu, Yanrong Liu, Guolin Zhao, Lai‐Yu Kwok, Zheng Sun, Zhihong Sun, Wenyi Zhang   +8 more
wiley   +1 more source

Shotgun Contigs Statistics

, 2023
Illumina shotgun reads from the fecal microbiomes of two domestic cats were assembled into contigs with ...
Connie A. Rojas (13997751)
core   +1 more source

Gut Microbial Topology and Metabolic Signatures Associated With Colorectal Neoplasia

Advanced Science, EarlyView.
The gut microbiota organizes into two robust association patterns linked to colorectal neoplasia risk. Topological shifts in microbial networks are associated with metabolite alterations and may shape host responses during disease development. ABSTRACT Alterations of gut microbial communities impact health.
Kai Song, Youwen Qin, Jiahui Luo, Liping Liu, Chenyu Luo, Yinbin Qiu, Yiyi Zhong, Huanzi Zhong, Kui Wu, Meng Ni, Dong Wu, Min Dai, Shida Zhu, Hongda Chen   +13 more
wiley   +1 more source

The Potential of Pequi Oil as a Modulator of Chaperone Expression to Minimize Heat Stress in Laying Hens

Agriculture
Pequi oil (PO) is a natural feed additive rich in bioactive compounds, which can modulate antioxidant and immunological systems. Thus, the aim of this study was to evaluate the proteomic profile of laying hens supplemented with PO under heat stress ...
Paola Aparecida Damázio Rodrigues, Joyce Andrade da Silva, José Cavalcante Souza Vieira, Gabrieli Andressa de Lima, Laís Garcia Cordeiro, Elis Omar Figueroa Castillo, Júlia de Lima Lopes, Marília Afonso Rabelo Buzalaf, Pedro de Magalhães Padilha, José Roberto Sartori   +9 more
doaj   +1 more source

Fishing in the Soup – Pathogen Detection in Food Safety Using Metabarcoding and Metagenomic Sequencing

Frontiers in Microbiology, 2019
In food safety the detection of food contaminations with pathogenic microorganisms is a race against time and often outpaced by error-prone epidemiological approaches. For evidence-based outbreak investigations fast and reliable techniques and procedures
Josephine Grützke, Burkhard Malorny, Jens Andre Hammerl, Anne Busch, Simon H. Tausch, Herbert Tomaso, Carlus Deneke   +6 more
doaj   +1 more source

Lung abscess by Fusobacterium nucleatum and Streptococcus spp. co-infection by mNGS: A case series

Open Life Sciences, 2023
The aim of this article was to employ shotgun mNGS for pathogen diagnosis in three patients with lung abscesses. The pleural fluid or bronchoalveolar lavage fluid from patients was sent to traditional culture and the shotgun mNGS test. Laboratory culture
Wang Na, Gao Zhichao, He Shuai, Han Mengzhen, Han Wenjie, Liu Xiaolin, Cao Hui, Jing Mingxi, Sun Tao, Xu Junnan   +9 more
doaj   +1 more source

Omnidirectional Interaction Networks Modulating Phenotypic Plasticity in the Gut Microbiota Towards Ulcerative Colitis

Advanced Science, EarlyView.
This study employs a spouse‐pair cohort design and an idopNetwork model that integrates evolutionary game theory, predator‐prey dynamics, and developmental modularity theory to reconstruct maximally informative microbial interaction networks. This approach reveals how interspecies interactions drive the phenotypic plasticity of the gut microbiota in ...
Huizhen Li, Jiayi Li, Ang Dong, Xiaoyan Guo, Qiuyue Tu, Zelin Feng, Haojia Lin, Yanru Zhang, Yuxuan Hao, Huiying Gong, Yihan Meng, Yu Wang, Shing‐Tung Yau, Xiaocang Cao, Rongling Wu, Xinjuan Liu   +15 more
wiley   +1 more source

Shotgun Metagenomic Characterization of Acne Microbiota Before and After Treatment with a Topical Biotechnological Phytocomplex: Understanding Skin Dysbiosis

Microorganisms
This study assessed the impact of a topical phytocomplex on the acne skin microbiota, encompassing bacterial, fungal, and phage communities. Skin samples obtained from participants exhibiting a positive response to the treatment were analyzed using high ...
Adrià Cruells, Cristina Eguren, Aymée Robainas Barcia, Helena Martínez, Mohammed Sharaf, Carlos Ruiz, Antonio Sánchez-Baos, Nerea Carrón, Lola Bou, Montse Pérez, Raúl De Lucas, Aurora Guerra-Tapia   +11 more
doaj   +1 more source