Results 51 to 60 of about 203,392 (300)

Novel applications of shotgun phage display [PDF]

, 2004
In a shotgun phage display library, theoretically, the entire proteome of a bacterium is represented. Phages displaying specific polypeptides can be isolated by affinity selection, while the corresponding gene remains physically linked to the gene ...
Rosander, Anna
core  

The Vaginal Microbiome: Disease, Genetics and the Environment [PDF]

, 2010
The vagina is an interactive interface between the host and the environment. Its surface is covered by a protective epithelium colonized by bacteria and other microorganisms.
Bin Xie, Christopher J. Friedline, Cynthia N. Cornelissen, Elizabeth C. Prom-Wormley, Federico A. Puma, Gregory A. Buck, Huan Mo, James P. Brooks, Jennifer M. Fettweis, Jerome L. Strauss, Joao P. Alves, Joseph F. Borzelleca, Judy L. Silbert, Kimberly K. Jefferson, Lindon J. Eaves, Logan Voegtly, Maria C. Rivera, Mark A. Reimers, Michael D. Harwich, Michael C. Neale, Myrna G. Serrano, Nihar U. Sheth, Philippe Girerd, Seth B. Roberts, Stephanie L. Hendricks, Timothy P. York, Vladimir Lee, Xi Gao, Yuan Gao   +28 more
core   +3 more sources

Gemella morbillorum Promotes Colorectal Carcinogenesis: LPBDCP‐Mediated Invasion Activates Ras Signaling and Destabilizes p53

Advanced Science, EarlyView.
ABSTRACT Gut microbiota dysbiosis promotes colorectal cancer (CRC) tumorigenesis. A global fecal metagenomic analysis identified Gemella morbillorum as a key contributor to the CRC‐associated microbiota. Fluorescence in situ hybridization revealed that Gemella morbillorum is enriched in CRC tumor tissues compared to adjacent normal tissues.
Zhen Wang, Jia Zhang, Haojie Lu, Jingjing Ni, Shuaishuai Yang, Yuting Shi, Shuo Zhang, Pei Zhang, Li Liu   +8 more
wiley   +1 more source

Fishing in the Soup – Pathogen Detection in Food Safety Using Metabarcoding and Metagenomic Sequencing

Frontiers in Microbiology, 2019
In food safety the detection of food contaminations with pathogenic microorganisms is a race against time and often outpaced by error-prone epidemiological approaches. For evidence-based outbreak investigations fast and reliable techniques and procedures
Josephine Grützke, Burkhard Malorny, Jens Andre Hammerl, Anne Busch, Simon H. Tausch, Herbert Tomaso, Carlus Deneke   +6 more
doaj   +1 more source

Violently Possessed: Johnson as the Vehicle for limiting Sentencing Enhancement under the Armed Career Criminals Act [PDF]

, 2015
This commentary previews an upcoming Supreme Court case, Johnson v. United States in which the Court will decide whether conviction for mere possession of a short-barreled shotgun qualifies as a violent felony that warrants sentence-enhancement under ...
Robe, Jonathan
core   +1 more source

ShotgunWSD: An unsupervised algorithm for global word sense disambiguation inspired by DNA sequencing

, 2017
In this paper, we present a novel unsupervised algorithm for word sense disambiguation (WSD) at the document level. Our algorithm is inspired by a widely-used approach in the field of genetics for whole genome sequencing, known as the Shotgun sequencing ...
Butnaru, Andrei M., Hristea, Florentina, Ionescu, Radu Tudor   +2 more
core   +1 more source

From Pine Cones to Read Clouds: Rescaffolding the Megagenome of Sugar Pine (Pinus lambertiana). [PDF]

, 2017
We investigate the utility and scalability of new read cloud technologies to improve the draft genome assemblies of the colossal, and largely repetitive, genomes of conifers.
Crepeau, Marc W, Langley, Charles H, Stevens, Kristian A   +2 more
core   +2 more sources

Combination Immunotherapy as a Promising Strategy to Overcome Immunotherapy Resistance: From Emergence to Next‐Generation Approaches

Advanced Science, EarlyView.
This review examines emerging combination immunotherapy strategies tailored to distinct tumor microenvironments and highlights next‐generation biomarkers that guide response prediction and treatment personalization. It integrates lessons from unsuccessful trials, addresses toxicity challenges, and outlines approaches for early biomarker discovery and ...
Asmita Pandey, Sudhir Kumar Rai, Li Ma, Lauren Higa, Vedbar Khadka, Hua Yang, Youping Deng   +6 more
wiley   +1 more source

The Potential of Pequi Oil as a Modulator of Chaperone Expression to Minimize Heat Stress in Laying Hens

Agriculture
Pequi oil (PO) is a natural feed additive rich in bioactive compounds, which can modulate antioxidant and immunological systems. Thus, the aim of this study was to evaluate the proteomic profile of laying hens supplemented with PO under heat stress ...
Paola Aparecida Damázio Rodrigues, Joyce Andrade da Silva, José Cavalcante Souza Vieira, Gabrieli Andressa de Lima, Laís Garcia Cordeiro, Elis Omar Figueroa Castillo, Júlia de Lima Lopes, Marília Afonso Rabelo Buzalaf, Pedro de Magalhães Padilha, José Roberto Sartori   +9 more
doaj   +1 more source

Proteomics Is Analytical Chemistry: Fitness-for-Purpose in the Application of Top-Down and Bottom-Up Analyses

Proteomes, 2015
Molecular mechanisms underlying health and disease function at least in part based on the flexibility and fine-tuning afforded by protein isoforms and post-translational modifications.
Jens R. Coorssen, Alfred L. Yergey
doaj   +1 more source