Results 51 to 60 of about 106,975 (303)

Proteomics Is Analytical Chemistry: Fitness-for-Purpose in the Application of Top-Down and Bottom-Up Analyses

Proteomes, 2015
Molecular mechanisms underlying health and disease function at least in part based on the flexibility and fine-tuning afforded by protein isoforms and post-translational modifications.
Jens R. Coorssen, Alfred L. Yergey
doaj   +1 more source

A Postbiotic‐Inducing Ganoderma applanatum Polysaccharide Repairs the Intestinal Barrier via a Phocaeicola vulgatus ‐ Tridecylic Acid Axis

Advanced Science, EarlyView.
This study identifies GAP2, a bioactive polysaccharide fraction derived from Ganoderma applanatum, as a postbiotic inducer that repairs intestinal barrier damage in a gut microbiota‐dependent manner. GAP2 enriches Phocaeicola vulgatus, which degrades GAP2 and promotes tridecylic acid production, triggering Rho/CDC42 signaling and tight‐junction ...
Chuan Zhang, Miaoyu Li, Tiantian Li, Xiaojie Zang, Haiyang Shi, Yaru Liu, Chengcheng Zhang, Jianxin Zhao, Qixiao Zhai, Wei Chen, Fengwei Tian   +10 more
wiley   +1 more source

First Metagenomic Shotgun Sequencing Report on the Microbiome of Local Goat and Sheep Raw Milk in Benin for Dairy Valorization

DNA
Background/Objectives: Goat and sheep farming is an important agro-economic resource in Benin. However, their milk is both underutilized and insufficiently characterized, which limits the development of innovative dairy products and raises concerns about
Yvette Adje, Philippe Sessou, Konstantinos Tegopoulos, Yaovi Mahuton Gildas Hounmanou, Nikistratos Siskos, Ioanna Farmakioti, Paulin Azokpota, Souaïbou Farougou, Lamine Baba-Moussa, George Skavdis, Maria E. Grigoriou   +10 more
doaj   +1 more source

Mass Spectrometry Based Lipidomics: An Overview of Technological Platforms

Metabolites, 2012
One decade after the genomic and the proteomic life science revolution, new ‘omics’ fields are emerging. The metabolome encompasses the entity of small molecules—Most often end products of a catalytic process regulated by genes and proteins—with the ...
Harald C. Köfeler, Alexander Fauland, Gerald N. Rechberger, Martin Trötzmüller   +3 more
doaj   +1 more source

Structural Variants in the Human Genome Associated With Gut Microbiome and Blood Metabolic Traits With Potential Causal Links

Advanced Science, EarlyView.
Based on a multi‐omics cohort of 2002 individuals comprising high‐depth whole‐genome and metagenomic sequencing data, blood metabolites, and detailed questionnaires, we identified 138 859 high‐confidence SVs, uncovering 36 significant SV–microbiome associations and 48 SV–blood metabolite associations.
Qun Zhou, Keqing Wang, Junhong Chen, Haoyu Wang, Xinjiang Tan, Xuanlin Huang, Zhiyin Lin, Xun Xu, Xin Jin, Shaoqiao Zhang, Liang Xiao, Yuanqiang Zou, Tao Zhang, Xiaomin Liu   +13 more
wiley   +1 more source

Shotgun House, circa 1991

A view of a shotgun house. Text from slide presentation: Shotgun houses are narrow, front-gabled dwellings one room wide and two to three rooms deep. They get their name because it was said you can stand on the front porch of a shotgun house and shoot ...

core   +3 more sources

Eye injuries caused by shotgun and air-rifles treated at the University eye clinic in Belgrade 2000-2009 [PDF]

Srpski Arhiv za Celokupno Lekarstvo, 2014
Introduction. Eye injuries caused by shotgun buckshot or air-rifle bullets are not common but are very severe, causing blindness of the injured eye. Objective.
Jovanović Miloš B.
doaj   +1 more source

Engineered Chiral Probiotics Ameliorate MASH via Gut–Liver Axis

Advanced Science, EarlyView.
A chiral gold nanozyme was coated onto the gut commensal bacterium Faecalibacterium duncaniae (F. duncaniae) to create an engineered probiotic. In mouse models of MASH, this orally administered living therapeutic protected the bacterium against oxidative stress, enhanced its gut colonization, reversed steatosis, inflammation, and fibrosis, and improved
Jing Chen, Shen Zhang, Yuli Zhu, Da Zhou, Chunya Ji, Mingrui Zhu, Sirui Wang, Yuting Shen, Jifeng Yu, Heng Zhang, Yan Fang, Huixiong Xu, Haohao Yin   +12 more
wiley   +1 more source

Core of the saliva microbiome: an analysis of the MG-RAST data

BMC Oral Health, 2021
Background Oral microbiota is considered as the second most complex in the human body and its dysbiosis can be responsible for oral diseases. Interactions between the microorganism communities and the host allow establishing the microbiological proles ...
Simone G. Oliveira, Rafaela R. Nishiyama, Claudio A. C. Trigo, Ana Luiza Mattos-Guaraldi, Alberto M. R. Dávila, Rodrigo Jardim, Flavio H. B. Aguiar   +6 more
doaj   +1 more source

Using photovoice to understand community perceptions of firearm risks and protective factors among Asian Americans

American Journal of Community Psychology, EarlyView.
Abstract This study used photovoice methodology to explore Asian Americans' perspectives on the root causes and protective factors of firearm violence in their communities. Photovoice provided a participatory platform for community members to document lived experiences and identify priorities for change.
Tsu‐Yin Wu, Szu‐Hsien Chen, Xining Yang, Ken Resnicow, Hsing‐Fang Hsieh   +4 more
wiley   +1 more source