Results 151 to 160 of about 10,714 (176)

Proteolysis-Targeting Chimera Molecules Targeting SHP2

Future Medicinal Chemistry, 2022
Hua Li, Hua Li, Lixia Chen
exaly  

AZABICYCLIC SHP2 INHIBITORS

2022
CIAMMAICHELLA ALINA, DI FABIO ROMANO, FERRIGNO FEDERICA, FEZZARDI PAOLA, MONTALBETTI CHRISTIAN, PETROCCHI ALESSIA, RELITTI NICOLA, ROSSETTI ILARIA, SFERRAZZA ALESSIO, TORRENTE ESTHER, FERRANTE LUCA, GRILLO ALESSANDRO   +11 more
openaire   +3 more sources

Phase Separation of Disease-Associated SHP2 Mutants Underlies MAPK Hyperactivation

Cell, 2020
Zhong-Yin Zhang, , Jidong Zhu
exaly  

SHP2

2018
openaire   +1 more source

PYRIMIDINONE DERIVATIVES AS SHP2 ANTAGONISTS

2020
JORAND-LEBRUN CATHERINE, BOIVIN ROCH, JOHNSON THERESA, WANG YANPING, XIAO YUFANG, CHEN XIAOLING, LINDE NINA, MUSCH DOREEN, KUMAR DEEPAK   +8 more
openaire   +4 more sources

Therapeutic potential of targeting SHP2 in human developmental disorders and cancers

European Journal of Medicinal Chemistry, 2020
Tingkai Chen, Meiyang Xi, Runpu Shen
exaly  

Shp2 Inhibits Proliferation of Esophageal Squamous Cell Cancer via Dephosphorylation of Stat3

International Journal of Molecular Sciences, 2017
Hua Tang, Min Jie, Xu Zhifei
exaly  

INHIBITORS OF SHP2

2019
BRÜGGEMEIER ULF, SCHOMBER TIBOR, DRÖBNER KAROLINE, ENGEL DAVID, BECKER MICHAEL   +4 more
openaire   +1 more source

Shp2 Plays a Critical Role in IL-6-Induced EMT in Breast Cancer Cells

International Journal of Molecular Sciences, 2017
, Ruifang Niu, Niu Ruifang
exaly  

Shp2 expression is upregulated in cervical cancer, and Shp2 contributes to cell growth and migration and reduces sensitivity to cisplatin in cervical cancer cells

Pathology Research and Practice, 2019
Dan Gao, , Mengcao Cao
exaly