Results 51 to 60 of about 343,438 (289)

A Fracture Mechanics-based Method for Prediction of Cracking of Circular and Elliptical Concrete Rings under Restrained Shrinkage [PDF]

open access: yes, 2014
This article has been made available through the Brunel Open Access Publishing Fund.A new experimental method, utilizing elliptical ring specimens, is developed for assessing the likelihood of cracking and cracking age of concrete subject to restrained ...
Dong, W   +5 more
core   +1 more source

Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics

open access: yesFEBS Letters, EarlyView.
Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt   +8 more
wiley   +1 more source

Free iron oxides modulate the surface properties of Benggang soil on Southern China: insights into erosive mechanisms

open access: yesFrontiers in Environmental Science
Benggang, an erosional phenomenon located in southern China, exhibits distinctive characteristics that can have profound ecological and agricultural consequences as well as pose risks to human life.
Ling Jiang   +6 more
doaj   +1 more source

From junk to function — How weak selection in eukaryotes builds new parts and drives genomic complexity

open access: yesFEBS Letters, EarlyView.
How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley   +1 more source

shrinkage [PDF]

open access: yes, 2014
Citation: 'shrinkage' in the IUPAC Compendium of Chemical Terminology, 3rd ed.; International Union of Pure and Applied Chemistry; 2006. Online version 3.0.1, 2019. 10.1351/goldbook.ST07632 • License: The IUPAC Gold Book is licensed under Creative Commons Attribution-ShareAlike CC BY-SA 4.0 International for individual terms.
openaire   +2 more sources

The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation

open access: yesFEBS Letters, EarlyView.
Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge   +6 more
wiley   +1 more source

From Minimax Shrinkage Estimation to Minimax Shrinkage Prediction

open access: yesStatistical Science, 2012
Published in at http://dx.doi.org/10.1214/11-STS383 the Statistical Science (http://www.imstat.org/sts/) by the Institute of Mathematical Statistics (http://www.imstat.org)
George, Edward I, Liang, Feng, Xu, Xinyi
openaire   +4 more sources

Stimulator of interferon genes agonist augmented antitumor immunity of osimertinib in Egfr‐mutated lung cancer

open access: yesMolecular Oncology, EarlyView.
Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura   +19 more
wiley   +1 more source

Lightweight concrete for 3D-printing with internal curing agent for Portland cement hydration

open access: yesMagazine of Civil Engineering, 2022
The development of 3D printing technology requires solving material science problems to ensure the rheology of concrete mixtures with controlled mobility and high retention of volume after extrusion and also the creation of favorable conditions for the ...
Inozemtcev Aleksandr   +2 more
doaj   +1 more source

Wavelet shrinkage using adaptive structured sparsity constraints [PDF]

open access: yes, 2015
Structured sparsity approaches have recently received much attention in the statistics, machine learning, and signal processing communities. A common strategy is to exploit or assume prior information about structural dependencies inherent in the data ...
Tomassi, Diego Rodolfo   +7 more
core   +1 more source

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