Results 141 to 150 of about 1,450,984 (187)

Interpretable Machine Learning Model for Fungal Infection Prediction: A Real‐World Study

open access: yesHealth Care Science, Volume 5, Issue 5, Page 473-486, October 2026.
Our study successfully developed and validated a machine learning model based on large‐scale electronic health record data to predict the risk of fungal infections in hospitalized patients. Through a Streamlit‐powered web platform, the model was seamlessly embedded into clinical workflows, completing the full pipeline from model construction to real ...
Jinru Yang   +5 more
wiley   +1 more source

Exposure–Response Analyses of Ropeginterferon Alfa‐2b in Essential Thrombocythemia

open access: yesThe Journal of Clinical Pharmacology, Volume 66, Issue 10, October 2026.
Abstract Ropeginterferon alfa‐2b is a new‐generation interferon therapy for the treatment of myeloproliferative neoplasms (MPNs), including essential thrombocythemia (ET). This investigation was designed to characterize its population pharmacokinetics–pharmacodynamics (PopPK‐PD) and delineate exposure–response (E‐R) relationships in ET. A population PK
Albert Qin   +20 more
wiley   +1 more source

The Discrepancy Between Estimated GFR Cystatin C and Estimated GFR Creatinine at 3 Months After Hospitalization and Long-Term Adverse Outcomes. [PDF]

open access: yesKidney Int Rep
Wen Y   +17 more
europepmc   +1 more source

The Natural History of Residual and Recurrent Disease in Advanced Juvenile Nasopharyngeal Angiofibroma: A Systematic Review

open access: yesThe Laryngoscope, Volume 136, Issue 10, Page 4130-4138, October 2026.
Residual and recurrent disease in advanced juvenile nasopharyngeal angiofibromas (JNAs) demonstrate spontaneous involution, reduction in size, or long‐term stability following initial treatment in 95% of patients. In this systematic review of 131 patients with advanced JNA, only 2% of patients demonstrated disease progression during surveillance, but ...
Shivani Angelique Kumar   +2 more
wiley   +1 more source

Glycoproteomic Signatures of IgG Subclass N‐Glycosylation Reveal Molecular Endotypes in Idiopathic Inflammatory Myopathies

open access: yesMedComm, Volume 7, Issue 10, October 2026.
• EThcD‐sceHCD‐MS/MS and updated PANDA software decode IgG N‐glycosylation in IIMs. • Unsupervised clustering reveals three novel glyco‐endotypes matching clinical phenotypes. • A seven‐glycopeptide model enables robust endotype prediction beyond conventional subtypes.
Tong Wu   +9 more
wiley   +1 more source

Cytoskeletal Dynamics in Cancer: From Pathogenesis to Treatment

open access: yesMedComm, Volume 7, Issue 10, October 2026.
This review systematically addresses the fundamental roles of the cytoskeleton (actin filaments, microtubules, and intermediate filaments) in cancer progression. We focus on how cytoskeletal dynamics regulate tumor proliferation, metastasis, and programmed cell death, while also modulating the immune microenvironment. Understanding these mechanisms may
Jie Chen   +9 more
wiley   +1 more source

Colorectal Cancer: Epidemiology, Risk Factors, Signaling Pathways, Clinical Features, Screening, Diagnosis, and Management

open access: yesMedComm, Volume 7, Issue 10, October 2026.
Colorectal cancer is a heterogeneous, adaptive disease shaped by population‐level risk, genomic and epigenetic alterations, tumor ecosystem evolution, and treatment pressure. This review integrates epidemiology, risk factors, signaling networks, clinical presentation, screening, molecular diagnosis, and stage‐ and biomarker‐guided management while ...
Kairui Wan   +6 more
wiley   +1 more source

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