Interpretable Machine Learning Model for Fungal Infection Prediction: A Real‐World Study
Our study successfully developed and validated a machine learning model based on large‐scale electronic health record data to predict the risk of fungal infections in hospitalized patients. Through a Streamlit‐powered web platform, the model was seamlessly embedded into clinical workflows, completing the full pipeline from model construction to real ...
Jinru Yang +5 more
wiley +1 more source
Association between the difference in estimated GFR based on cystatin C versus creatinine in coronary artery diseases. [PDF]
Liu Z, Jiang W, Song Y, Dou K, Song W.
europepmc +1 more source
Exposure–Response Analyses of Ropeginterferon Alfa‐2b in Essential Thrombocythemia
Abstract Ropeginterferon alfa‐2b is a new‐generation interferon therapy for the treatment of myeloproliferative neoplasms (MPNs), including essential thrombocythemia (ET). This investigation was designed to characterize its population pharmacokinetics–pharmacodynamics (PopPK‐PD) and delineate exposure–response (E‐R) relationships in ET. A population PK
Albert Qin +20 more
wiley +1 more source
The Discrepancy Between Estimated GFR Cystatin C and Estimated GFR Creatinine at 3 Months After Hospitalization and Long-Term Adverse Outcomes. [PDF]
Wen Y +17 more
europepmc +1 more source
Residual and recurrent disease in advanced juvenile nasopharyngeal angiofibromas (JNAs) demonstrate spontaneous involution, reduction in size, or long‐term stability following initial treatment in 95% of patients. In this systematic review of 131 patients with advanced JNA, only 2% of patients demonstrated disease progression during surveillance, but ...
Shivani Angelique Kumar +2 more
wiley +1 more source
Advances in <i>Pseudomonas aeruginosa</i>-Induced Programmed Cell Death and Potential Targeted Treatment Strategies. [PDF]
Tan C, Luo Y.
europepmc +1 more source
• EThcD‐sceHCD‐MS/MS and updated PANDA software decode IgG N‐glycosylation in IIMs. • Unsupervised clustering reveals three novel glyco‐endotypes matching clinical phenotypes. • A seven‐glycopeptide model enables robust endotype prediction beyond conventional subtypes.
Tong Wu +9 more
wiley +1 more source
Cytoskeletal Dynamics in Cancer: From Pathogenesis to Treatment
This review systematically addresses the fundamental roles of the cytoskeleton (actin filaments, microtubules, and intermediate filaments) in cancer progression. We focus on how cytoskeletal dynamics regulate tumor proliferation, metastasis, and programmed cell death, while also modulating the immune microenvironment. Understanding these mechanisms may
Jie Chen +9 more
wiley +1 more source
Hierarchical Porous Egg White Hydrogel Promotes Diabetic Wound Closure through Topography-Guided Cell Recruitment. [PDF]
Su T +9 more
europepmc +1 more source
Colorectal cancer is a heterogeneous, adaptive disease shaped by population‐level risk, genomic and epigenetic alterations, tumor ecosystem evolution, and treatment pressure. This review integrates epidemiology, risk factors, signaling networks, clinical presentation, screening, molecular diagnosis, and stage‐ and biomarker‐guided management while ...
Kairui Wan +6 more
wiley +1 more source

