Eco-friendly green synthesis of silver nanoparticles from guajava leaves extract for controlling organophosphorus pesticides hazards, characterization, and in-vivo toxicity assessment. [PDF]
Albadawi EA +5 more
europepmc +1 more source
BTK inhibitors suppress malignant B‐cell signaling while simultaneously reshaping immune regulation through effects on T cells and the tumor microenvironment. These mechanisms support combination immunotherapy strategies and also underlie the expanding application of BTK inhibitors in solid tumors, autoimmune and inflammatory diseases.
Miao Sun, Dengju Li, Jia Wei
wiley +1 more source
Information Design for Early‐Stage Dose‐Finding Trials
ABSTRACT To enhance enrollment rates in early‐stage dose‐finding clinical trials, we propose an information design approach, where the clinical investigator (CI) commits to an information releasing mechanism (IRM) based on the treatment's uncertain efficacy and toxicity to encourage patients to participate in the trial.
Amin Khademi, Ningyuan Chen
wiley +1 more source
Perspectives of parents of children with Dravet syndrome indicate that extreme heat and high temperatures exacerbate epileptic seizures, introduce new seizure triggers, and require the adoption of specific seizure‑management strategies. This original article is commented by Hood on pages 1338–1339 of this issue.
Angel Aledo‐Serrano +8 more
wiley +1 more source
Neutrophil-Membrane Biomimetic Hollow Mesoporous Silica Nanoparticles for Targeted Delivery of Imperatorin to Alleviate Cerebral Ischemia-Reperfusion Injury via Nrf2/ARE/Keap1 Pathway. [PDF]
Chen F +10 more
europepmc +1 more source
ABSTRACT The combination of geographical factors (climate, slope, orientation, lithology, water availability, etc.) and the pathogenicity of agents such as the oomycete from the kingdom Straminopile Phytophthora or Pythium species causes the plant disease known as oak decline in the Iberian Peninsula. Leaving aside the presence of the pathogen, the aim
Mario Corral Ribera +2 more
wiley +1 more source
Aflatoxin B1 triggers ferroptosis via inhibiting the NRF2 signaling pathway in duck granulosa cells. [PDF]
Chen Y +11 more
europepmc +1 more source
Abstract Kenya's aquaculture sector is at a pivotal stage, transitioning from a historical reliance on Nile tilapia and African catfish toward a more diversified production portfolio that integrates indigenous and emerging freshwater and marine species. This shift is increasingly recognized as essential to enhance climate resilience, food security, and
Jonathan Munguti +9 more
wiley +1 more source
Selenoprotein P Deficiency Is Associated with Early Signs of Kidney Disease and Hospitalization Risk in Heart Failure. [PDF]
Ohlsson MA +9 more
europepmc +1 more source
The miR167–ARF8 module coordinates stamen–pistil development and fruit set in tomato
SlMIR167a is the functionally prominent SlMIR167 gene in tomato fruit development. Summary Auxin is an important regulator of reproductive development. The families of the AUXIN RESPONSE FACTOR (ARF) genes, important components of the auxin signal, have expanded in flowering plants.
Nave Man +7 more
wiley +1 more source

