Results 171 to 180 of about 1,450,984 (187)

Associations of Body Composition Biomarkers with Survival, Cardiovascular Events, and Progression in Persons with Chronic Kidney Disease: Insights from the Renal Risk in Derby Study.

Am J Nephrol
Randhay A, Selby NM, Taal MW, Eldehni MT.   +3 more
europepmc   +1 more source

Shrunken pore syndrome in childhood cancer survivors treated with potentially nephrotoxic therapy [PDF]

Scandinavian Journal of Clinical and Laboratory Investigation, 2022
Childhood cancer survivors (CCS) are at risk of kidney dysfunction. Recently, the shrunken pore syndrome (SPS) has been described, which is characterized by selectively impaired filtration of larger molecules like cystatin C, while filtration of smaller ...
Esmee C M Kooijmans, Saskia M F Pluijm, Andrica C H de Vries   +2 more
exaly   +11 more sources

eGFR, cystatin C and creatinine in shrunken pore syndrome

Clinica Chimica Acta, 2019
Shrunken pore syndrome (SPS) is a condition in which the estimated glomerular filtration rate (eGFR) based on serum/plasma cystatin C concentration is significantly lower than the eGFR based on creatinine.
Ning Xu
exaly   +2 more sources

Shrunken pore syndrome - a common kidney disorder with high mortality. Diagnosis, prevalence, pathophysiology and treatment options

Clinical Biochemistry, 2020
Invasive studies show that the glomerular sieving coefficients for 5–30 kDa plasma proteins in the human kidney may be selectively reduced compared to those for small molecules < 0.9 kDa, commonly used to measure glomerular filtration rate (GFR ...
Anders Grubb
exaly   +3 more sources

The shrunken pore syndrome is associated with declined right ventricular systolic function in a heart failure population – the HARVEST study [PDF]

Scandinavian Journal of Clinical and Laboratory Investigation, 2016
The close relationship between heart and kidney diseases was studied with respect to the ‘Shrunken pore syndrome’ that is characterized by a difference in renal filtration between cystatin C and creatinine.
Erasmus Bachus, Anders Grubb, Hannes Holm   +2 more
exaly   +3 more sources

Proteins linked to atherosclerosis and cell proliferation are associated with the shrunken pore syndrome in heart failure patients

Proteomics - Clinical Applications, 2021
PURPOSE: The "Shrunken pore syndrome" (SPS) is characterized by a difference in renal filtration between cystatin C and creatinine, resulting in a low eGFRcystatinC /eGFRcreatinine -ratio.
Erasmus Bachus, Anders Grubb, Hannes Holm   +2 more
exaly   +2 more sources

Mild impairment of renal function (shrunken pore syndrome) is associated with increased risk of a future first-ever myocardial infarction in women

Scandinavian Journal of Clinical and Laboratory Investigation, 2021
Impaired renal function is associated both with the development of cardiovascular disease and its prognosis. A new syndrome called ' Shrunken Pore Syndrome ' has been suggested, as the estimated glomerular filtration rate for cystatin C (eGFR(cystatin C))
Elisabet Söderström, Stefan Söderberg, Torbjörn K Nilsson   +2 more
exaly   +2 more sources

Shrunken pore syndrome and mortality: a cohort study of patients with measured GFR and known comorbidities

Scandinavian Journal of Clinical and Laboratory Investigation, 2020
Shrunken pore syndrome (SPS) is defined by a cystatin C-based estimation of glomerular filtration rate (eGFRCYS) being less than 60% or 70% of a creatinine-based GFR estimation (eGFRCR) in the absence of extrarenal influences on cystatin C or creatinine ...
Magnus Abrahamson, Anders Grubb, Anders Christensson   +2 more
exaly   +2 more sources

Cystatin C as a Multifaceted Biomarker in Kidney Disease and Its Role in Defining “Shrunken Pore Syndrome”

, 2017
Cystatin C, a basic nonglycosylated 13.3 kDa protein comprising a single polypeptide chain of 120 amino acid residues, is produced at a stable rate from a housekeeping gene in all nucleated cells and eliminated from the circulation by free filtration ...
A. Grubb, Grubb, A.
exaly   +3 more sources