Results 51 to 60 of about 4,290,946 (318)

From In‐Silico Optimized Microfabrication to Experimental Validation: Engineering a Tridimensional Epi‐Intraneural Interface

Advanced Functional Materials, EarlyView.
An epi‐intraneural interface is developed through in silico optimization and a novel tridimensional microfabrication pipeline. The device integrates penetrating and epineural contacts on a flexible substrate. Mechanical, electrochemical, and in vivo testing in rat and pig reveal robust implantation, low‐threshold activation, and site‐dependent ...
Federico Ciotti, Andrea Cimolato, Noemi Gozzi, Pietro Palopoli, Luca Brugnoli, Natalija Katic Secerovic, Rebecca Gallivan, Alexander Shokurov, Carlo Menon, Johannes Weichart, Ignacio Delgado‐Martinez, Weiguo Song, Stavros Zanos, Xavier Navarro, Stanisa Raspopovic   +14 more
wiley   +1 more source

Clinical Outcome and Safety of Lumboperitoneal Shunt in the Treatment of Non-Obstructive Hydrocephalus

Clinical Interventions in Aging, 2023
Ning-Ping Foo,1,2 Yang Chien Tun,3 Che Chao Chang,4,5 Hung-Lin Lin,3 Cheng-Hsin Cheng,2,4,* Hao-Yu Chuang4,6,* 1Department of Emergency, An Nan Hospital, China Medical University, Tainan, 70965 Taiwan; 2Graduate Institute of Medical Sciences ...
Foo NP, Tun YC, Chang CC, Lin HL, Cheng CH, Chuang HY   +5 more
doaj  

Precise Control of Drug Release in Machine Learning‐Designed Antibody‐Eluting Implants for Postoperative Scarring Inhibition in Glaucoma

Advanced Healthcare Materials, EarlyView.
We developed a micro‐sized, biocompatible implant for postoperative sustained delivery of anti‐fibrotic antibodies in glaucoma surgery. Machine learning‐guided optimization of polymer composition, implant geometry, and porosity enabled precise control of drug release.
Mengqi Qin, Wenbing Jiang, Kai Xin Thong, Zeynep Ulker, Brihitejas Patel, Cynthia Yu‐Wai‐Man   +5 more
wiley   +1 more source

Ventriculoperitoneal shunt infection rate and other associated complications of VP shunt insertion in Abuja, Nigeria

World Neurosurgery: X
Background: Complications associated with ventriculoperitoneal shunt insertion constitute a significant cause of morbidity and mortality among hydrocephalus patients.
Obinna M. Ayogu, Kenechukwu K. Igbokwe, Kassim M. Jabir, Efeomo D. Onobun, Cyril I. Okpata, Ugochukwu Ugwuanyi, Ikechi Ekpendu, Edidiong A. Essiet   +7 more
doaj   +1 more source

Four-dimensional microscope- integrated optical coherence tomography to enhance visualization in glaucoma surgeries

Indian Journal of Ophthalmology, 2017
We report the first use of swept-source microscope-integrated optical coherence tomography (SS-MIOCT) capable of live four-dimensional (4D) (three-dimensional across time) imaging intraoperatively to directly visualize tube shunt placement and ...
Neel Dave Pasricha, Paramjit Kaur Bhullar, Christine Shieh, Christian Viehland, Oscar Mijail Carrasco-Zevallos, Brenton Keller, Joseph Adam Izatt, Cynthia Ann Toth, Pratap Challa, Anthony Nanlin Kuo   +9 more
doaj   +1 more source

Transcatheter closure of a residual shunt with posteroinferior deficient rim after surgical closure of an ASD: a case report

BMC Cardiovascular Disorders, 2020
Background There are few reports in the literature of device closure of residual shunts following initial surgical closure of an atrial septal defect (ASD). This case study reports one such case.
Xicheng Deng, Taoyue Yao, Yefeng Wang, Guangxian Yang, Wenjuan Chen, Peng Huang, Zhi Chen   +6 more
doaj   +1 more source

Plasma‐Polymerized Nanoparticles Presenting Fibrillin‐1 Drive Rapid Re‐Endothelialization of Vascular Grafts

Advanced Healthcare Materials, EarlyView.
Commercial vascular grafts are made from ePTFE, a highly hydrophobic, foreign material that fails at a high rate in small‐diameter applications. Plasma polymer nanoparticles (PPN) are a versatile material functionalisation tool, used here to present fibrillin‐1 fragment PF8 on the graft surface.
Bob S. L. Lee, Yuen Ting Lam, Alex H. P. Chan, Praveesuda L. Michael, Timothy C. Mitchell, Jui Chien Hung, Miguel Santos, Khoon S. Lim, Richard P. Tan, Steven G. Wise   +9 more
wiley   +1 more source

Randomized preclinical study of machine perfusion in vascularized composite allografts

BJS (British Journal of Surgery), EarlyView., 2020
This study was designed to identify the optimum machine perfusion parameters for preservation of limbs before transplantation, and determine whether this was better than cold storage. Normothermic machine perfusion at a pressure of 70 mmHg (NMP‐70) provided superior preservation to cold storage after transplantation.
K. R. Amin, J. P. Stone, J. Kerr, A. Geraghty, L. Joseph, A. Montero‐Fernandez, J. K. Wong, J. E. Fildes   +7 more
wiley   +1 more source

Organic Bulk‐Heterojunction‐Integrated Flexible Perovskite Photodetection Arrays for High‐Speed Broadband Optical Communication

Advanced Science, EarlyView.
A flexible broadband photodetector is realized by integrating a perovskite with an organic bulk‐heterojunction. It achieves high external quantum efficiency (EQE) (>80% visible, >60% near‐infrared (NIR)), ultralow dark current, and fast response, enabling self‐powered, high‐detectivity operation.
Xin Hong, Kanghui Ke, Yu Gao, Jiazhi Meng, Bohua Deng, Haoyu Huang, Zhichun Si, H. Y. Fu, Feiyu Kang, Guodan Wei   +9 more
wiley   +1 more source

PARPi Combining Nanoparticle LIN28B siRNA for the Management of Malignant Ascites

Advanced Science, EarlyView.
This study demonstrates that co‐inhibition of LIN28B and PARP using siLin28b/DSSP@lip‐PEG‐FA nanoparticles in combination with the PARP inhibitor BMN673 effectively suppresses the accumulation of malignant ascites associated with advanced cancers.
Yan Fang, Qian Shen, Yao Lin, Jing Zhu, Xiaolan Zhu, Rui Huang, Yijia Wu, Feiyang Shen, Qian Li, Guopei Zheng, Zhe Zhang, Qian Chu, Junhao Hu, Jianfeng Shen   +13 more
wiley   +1 more source