Results 61 to 70 of about 76,493 (306)

Reciprocal control of viral infection and phosphoinositide dynamics

open access: yesFEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

PENGARUH KEBOCORAN EMERGENCY SHUT DOWN VALVE PADA PROSES BONGKAR MUAT DI MT. IHSAN 1

open access: yes, 2021
Intisari-Emergency shut down (ESD) adalah suatu system yang berfungsi untuk menutup atau menghentikan peralatan-peralatan yang berhubungan dengan sistem pemuatan serta apabila terjadi kerusakan pada pipa ESD valve dapat berakibat potensi bahaya bongkar ...
SATRIA, AJI NUGROHO
core  

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

open access: yesFEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho   +3 more
wiley   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

open access: yesFEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe   +3 more
wiley   +1 more source

COVID-19 Lockdown Time Capsule of South Africa, April 2020

open access: yesThe Thinker, 2020
South Af rica had one of the strictest Covid lockdowns in the world starting on the 26th of March and lasting for 35 days. With five weeks of quarantine where only essential services were open, all educational institutions, places of worship and ...
Various Authors
doaj   +1 more source

Could Anonymous really shut down the internet?

open access: yes, 2012
In a statement posted online last month, hacker collective Anonymous announced plans to shut down the internet. Yes, you read that right. Operation Global Blackout, planned for March 31, is apparently a protest against 'SOPA [Stop Online Piracy Act ...
Philip Branch (18925282)
core   +1 more source

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

open access: yesFEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva   +5 more
wiley   +1 more source

Bleb leak revision with Tenon's autograft

open access: yesAmerican Journal of Ophthalmology Case Reports
This video demonstrates two surgical cases where autologous Tenon grafts are used to shut down leaking trabeculectomies. Variations in this technique with a rotational graft and a hinge graft are explored.
Lauren E. Chen   +4 more
doaj   +1 more source

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

open access: yesFEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li   +2 more
wiley   +1 more source

Human Operators and Simulation within a Chemical Industry

open access: yesMeasurement + Control, 1977
A review is made of the practical application of simulation techniques in a chemical industry. The techniques include mass balance steady state models, sequential plant start-up and shut-down models and simple plant simulators.
R. M. M. Doig
doaj   +1 more source

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