Results 71 to 80 of about 76,493 (306)

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

Key Assembling Issues Relating to Mechanical Vibration of Fabricated Rotor of Large Induction Machines

open access: yesCommunications, 2019
In many applications, where rotating machines of high power are used, high demands on reliability and safety are laid. Precise manufacturing procedures has to be kept even in case of machines retrofits when e.g. rotors are newly assembled.
Vladimir Kindl   +3 more
doaj   +1 more source

Effect of pipe diameter on heat transfer characteristics of waxy crude oil pipeline during shutdown

open access: yesCase Studies in Thermal Engineering, 2020
Additional specific heat capacity method and momentum source term method are used to establish the mathematical model of the heat transfer process in different diameter waxy crude oil pipeline, and the finite volume method is used to solve the ...
Yue Zhao
doaj   +1 more source

FBI shuts down site that sold $80m worth of drugs, hitmen services and other illegal items.

open access: yes, 2013
US authorities the owner of Silk Road, a website which lived on the Deep Web and allowed users buy and sell illegal drugs using the virtual currency Bitcoin.

core  

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

open access: yesFEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai   +9 more
wiley   +1 more source

The planar cell polarity protein Vangl2 interacts with the PDZ‐domains of Scribble but not with a unique PDZ‐like domain in Inturned

open access: yesFEBS Letters, EarlyView.
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes   +4 more
wiley   +1 more source

Tau acetylation at K331 has limited impact on tau pathology in vivo

open access: yesFEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto   +3 more
wiley   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

open access: yesFEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa   +5 more
wiley   +1 more source

With pokies shut down, coronavirus stress could drive more people to reckless online gambling

open access: yes, 2022
With pokies shut down, coronavirus stress could drive more people to reckless online ...
Livingstone Charles (13894956)   +1 more
core   +1 more source

Probabilistic Operation of Electric Power Systems Considering Environmental Constraint (Part 15) -Consideration of Minimum Shut-down Time Constraints- [PDF]

open access: yes, 1989
application/pdfAn outline of already reported scheduling methods which can satisfy environmental constraints and give maximum reliability is briefly described. This scheduling method is expanded to consider the minimum shut-down time of the thermal power
33337   +3 more
core  

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