Results 81 to 90 of about 76,493 (306)

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

open access: yesFEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura   +2 more
wiley   +1 more source

Erosion in Steam General Tubes in Boiler and ID Fans in Coal Fired FBC Power Plant [PDF]

open access: yesMehran University Research Journal of Engineering and Technology, 2012
The FBC (Fluidized Bed Combustion) is a technique used to make solid particles behave like fluid and grow very fast for the power generation using low grade coal.
Shaheen Aziz   +2 more
doaj  

Diversity and complexity in neural organoids

open access: yesFEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

A tight MIP formulation of the unit commitment problem with start-up and shut-down constraints

open access: yesEURO Journal on Computational Optimization, 2017
This paper provides the convex hull description of the single thermal Unit Commitment (UC) problem with the following basic operating constraints: (1) generation limits, (2) start-up and shut-down capabilities, and (3) minimum up and down times.
C. Gentile, G. Morales-España, A. Ramos
doaj   +1 more source

PS shut down

open access: yes, 1968
A description of the major items of work which will be done on and around the 28 GeV proton synchrotron during the long shut down which has just ...

core  

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

open access: yesFEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz   +11 more
wiley   +1 more source

Renovation as a Catalyst for Change

open access: yesIn the Library with the Lead Pipe, 2011
Introduction This Lead Pipe post is about two libraries attempting to reinvent services, collections, and spaces as the walls of their buildings come crashing down.
Erin Dorney
doaj  

Get an Agreement or Shut It Down

open access: yes, 2018
Secretary of State Christopher takes an active role in the negotiations during the third week, but progress is slow. A frustrated Christopher tells Holbrooke to get an agreement or shut down the talks.
James W. Pardew
core   +1 more source

The ubiquitin ligase RNF115 is required for the clearance of damaged lysosomes

open access: yesFEBS Letters, EarlyView.
Upon lysosomal rupture, an E3 ubiquitin ligase RNF115 translocates from the cytosol to the damaged lysosomal membrane. Moreover, RNF115 depletion impairs the clearance of damaged lysosomes, identifying it as a key regulator of lysosomal quality control.
Sae Nakanaga   +3 more
wiley   +1 more source

Epigenetic blind spots – the role of DNA methylation dynamics in stem cell‐based models of embryogenesis

open access: yesFEBS Letters, EarlyView.
Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil   +4 more
wiley   +1 more source

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