Results 161 to 170 of about 78,383 (300)

PRMT9 Aggravated Dopaminergic Neurodegeneration in Parkinson's Disease Model by Facilitating the Degradation of DUSP26 and Inducing Mitochondrial Dysfunction

Advanced Science, EarlyView.
In the pathological state of PD induced by MPP+, the upregulated PRMT9 in dopaminergic neurons translocates into mitochondrion and interacts with DUSP26 and catalyzes its arginine methylation, leading to the ubiquitin‐proteasomal degradation of DUSP26 mediated by Trim32.
Tengfei Liu, Xiaomeng Song, Xin Guo, Rui Xiao, Ru Sun, Qiuran Ji, Lu Yu, Yiquan Li, Qingyi Fu, Qidi Xue, Lingjun Kong, Lin Chen, Chengjiang Gao, Huiqing Liu   +13 more
wiley   +1 more source

Mitigating the Shuttle Effect: 3D Covalent Organic Frameworks Anchoring Polysulfides for High-Performance Lithium–Sulfur Batteries

Lithium–sulfur batteries (LSBs) are promising candidates for next-generation high-performance batteries due to their high energy density, low cost, and environmental friendliness. However, issues such as low active material utilization, volume expansion,
Yiming Xie (106577), Zhiyang Wang (335420), Xiaowei Wu (2031751), Shanyue Wei (11864198), Can-Zhong Lu (1444486)   +4 more
core   +1 more source

Velocity and Acceleration of a Shuttle and Effects of Sweep

Sen'i Gakkaishi, 1949
Kamogawa, H., Kiuchi, A., Kitano, T.
openaire   +2 more sources

CREAT: A CRISPR‐Based Genome Trimming Strategy for Systematic Identification of Dispensable Regions and Rapid Genome Reduction

Advanced Science, EarlyView.
Current genome‐reduction methods work in a trial‐and‐error fashion, constituting a long‐standing bottleneck in the research. We developed CREAT (CRISPR‐based genome trimming with a multi‐homology‐arm template), a CRISPR‐based genetic approach that enables systematically classifying essential versus non‐essential genomic regions and subsequently ...
Guanhua Yuan, Zhe Gao, Yingxuan Qi, Yang Zhang, Xuhui Tian, Pengpeng Zhao, Xu Feng, Qunxin She   +7 more
wiley   +1 more source

Bridged h‐BN Nanosheets Coatings: Simultaneous Shielding Atomic‐Oxygen Irradiation and Achieving Superior Friction Performance

Advanced Science, EarlyView.
ABSTRACT To confront extreme space environments, a combination of inorganic and organic coatings can provide a pathway for offering highly durable radiation resistance and anti‐friction simultaneously. Herein, a strong interfacial 3D hydrogen‐bonding network is designed to create robust hexagonal boron nitride (h‐BN) based polymer coatings with ...
Zhuoyi Li, Changning Bai, Xingkai Zhang, Yusheng Liang, Wei Wu, Dingrui Zhou, Tao Du, Chunjin Wang   +7 more
wiley   +1 more source

Suppressing the Shuttle Effect in Lithium-Sulfur Batteries by a UiO-66-Modified Polypropylene Separator. [PDF]

ACS Omega, 2019
Fan Y, Niu Z, Zhang F, Zhang R, Zhao Y, Lu G.   +5 more
europepmc   +1 more source

TDP‐43 Aggregation: The Healthy‐Toxic Balance of the Prion‐Like Domain

Advanced Science, EarlyView.
TDP‐43 function relies on a delicate balance between reversible phase‐separated states and irreversible aggregation. Under physiological conditions, TDP‐43 forms dynamic droplets and oligomers that support normal cellular functions. In pathological contexts, this balance shifts toward aberrant aggregation, leading to toxic species.
Luca Zangrando, Emanuele Buratti, Francesca Paron   +2 more
wiley   +1 more source

Simultaneous Suppression of the Dendrite Formation and Shuttle Effect in a Lithium-Sulfur Battery by Bilateral Solid Electrolyte Interface. [PDF]

Adv Sci (Weinh), 2018
Fan L, Chen S, Zhu J, Ma R, Li S, Podila R, Rao AM, Yang G, Wang C, Liu Q, Xu Z, Yuan L, Huang Y, Lu B.   +13 more
europepmc   +1 more source

Radiation‐Induced Tumor‐Intrinsic LTβR N‐Glycosylation Suppresses Pyroptosis Through TRIM28‐Mediated PCBP2 SUMOylation to Promote Gastric Cancer Radioresistance

Advanced Science, EarlyView.
Radiotherapy triggers LTβR N‐glycosylation, enhancing its overall protein stability and nuclear retention. This accumulation drives TRIM28‐mediated PCBP2 SUMOylation, suppressing pyroptosis and conferring gastric cancer radioresistance. Therapeutically, a targeted nanoplatform (cRGD‐Lipo@EMD) effectively disrupts this regulatory axis, offering a highly
Weijie Zang, Yunlong Ji, Chunwang Zhou, Xiwen Li, Zhuang Lu, Guangze Zhang, Yu Chen, Wanjiang Xue, Yilin Hu   +8 more
wiley   +1 more source

Cosolvent Electrolyte Design for Li-S Batteries: Suppressing the Shuttle Effect via Phase Separation. [PDF]

Adv Mater
Yeo C, Kang S, Lee YJ, Choo S, Kim J, Yu SH, Park JW, Yoo DJ, Kim M.   +8 more
europepmc   +1 more source