Results 61 to 70 of about 16,195 (218)

Structural and biochemical analysis of a B12 superbinder

open access: yesFEBS Letters, EarlyView.
BtuG proteins are vitamin B12 scavengers in Bacteroides thetaiotaomicron, a dominant human gut bacterium. We present crystal structures of three BtuG homologs bound to cobalamin and its precursor cobinamide, revealing picomolar binding affinities, among the highest known for any natural protein.
Jose M. Martinez Felices   +3 more
wiley   +1 more source

From junk to function — How weak selection in eukaryotes builds new parts and drives genomic complexity

open access: yesFEBS Letters, EarlyView.
How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley   +1 more source

Effects of industrial hydrogen-rich gases on the performance of the spark ignition engine under various combustion modes

open access: yesCase Studies in Thermal Engineering
Hydrogen is emerging as a promising alternative to traditional fossil fuels for the transportation. Additionally, the hydrogen-rich gases (HRG) can produce on a large scale during the process of chemical production.
Xiongbo Duan   +3 more
doaj   +1 more source

Studi eksperimental pengaturan waktu pengapian pada mesin 4 langkah 1 silinder berbahan bakar E25

open access: yesMekanika, 2018
The use of ethanol as a mixture of premium is for reducing dependency to the primuim, considering that premium is not renewable. The goal of the ethanol addition in a fuel is to increase the octane number.
Arjuna AJi   +2 more
doaj   +1 more source

Prospecting the protein design landscape

open access: yesFEBS Letters, EarlyView.
This review outlines the current state of various protein design approaches. We discuss the current possibilities enabled by recently released tools, highlight future avenues to pursue in protein design, and underscore the crucial role of key databases and resources for successful protein design workflows.
Jakob R. Riccabona   +4 more
wiley   +1 more source

Theoretical Study of the Effects of Spark Timing on the Performance and Emissions of a Light-Duty Spark Ignited Engine Running under Either Gasoline or Ethanol or Butanol Fuel Operating Modes

open access: yesEnergies, 2017
Much research is ongoing to find suitable alternate fuels in order to reduce the exhaust emission levels without deteriorating the basic performance characteristics of conventional spark-ignited (SI) engines.
Roussos G. Papagiannakis   +2 more
doaj   +1 more source

L‐aspartate oxidase provides new insights into fumarate reduction in anaerobic darkness in Synechocystis sp. PCC6803

open access: yesFEBS Letters, EarlyView.
Synechocystis strains deficient in succinate dehydrogenase (SDH) secrete more succinate than the WT under dark anaerobic conditions, supporting that SDH then primarily acts as SDH, not as a fumarate reductase. L‐aspartate oxidase (Laspo) from Synechocystis is functional under anaerobic conditions, reducing fumarate to succinate.
Kateryna Kukil   +3 more
wiley   +1 more source

Artificial molecular machines and motors—Design and control of nanoscale motion

open access: yesFEBS Letters, EarlyView.
Molecules are constantly moving because of thermal fluctuations, but random motion alone cannot be exploited to perform directional tasks. Artificial molecular machines use chemical, electrical, or light energy to bias this motion. Molecular shuttles, rotary motors, and supramolecular pumps illustrate how nanoscale movement can be controlled and ...
Leonardo Andreoni, Alberto Credi
wiley   +1 more source

Turbulent spark-jet ignition in SI gas fuelled engine

open access: yesMATEC Web of Conferences, 2017
The article contains a thermodynamic analysis of a new combustion system that allows the combustion of stratified gas mixtures with mean air excess coefficient in the range 1.4-1.8.
Pielecha Ireneusz   +3 more
doaj   +1 more source

Smaller is better: nanobodies meet NMR

open access: yesFEBS Letters, EarlyView.
Nanobodies are single‐domain antigen‐binding fragments derived from camelid heavy chain antibodies. Their small size, high stability, and exceptional specificity make nanobodies uniquely useful probes for NMR studies of protein dynamics, transient conformational states, and protein–protein interactions.
Oleg Y. Dmitriev
wiley   +1 more source

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