Results 61 to 70 of about 15,498 (265)

Parametric Knocking Performance Investigation of Spark Ignition Natural Gas Engines and Dual Fuel Engines

Journal of Marine Science and Engineering, 2020
Both spark ignition (SI) natural gas engines and compression ignition (CI) dual fuel (DF) engines suffer from knocking when the unburnt mixture ignites spontaneously prior to the flame front arrival. In this study, a parametric investigation is performed
La Xiang, Gerasimos Theotokatos, Haining Cui, Keda Xu, Hongkai Ben, Yu Ding   +5 more
doaj   +1 more source

CFD Modelling of Flame Stretch in SI Engines

Energy Procedia, 2015
AbstractThe flame stretch is a phenomenon that affects the combustion initial stage in premixed charge Spark-Ignition (SI) engines with consequences on the laminar burning velocity, so its correct description is fundamental to predict the further turbulent flame development.In the context of a Computational Fluid Dynamics (CFD) investigation, two ...
SFORZA, LORENZO, LUCCHINI, TOMMASO, ONORATI, ANGELO   +2 more
openaire   +2 more sources

Structure‐forward targeting of claudins with synthetic binders

FEBS Letters, EarlyView.
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley   +1 more source

Discerning protein pools by selective staining with self‐labeling tags

FEBS Letters, EarlyView.
Cell surface proteins have an intra‐ and extracellular pool. Combining genetic fusion to self‐labeling tags that can be addressed with small molecule fluorophores allows separating these pools. We highlight recent developments and techniques for state‐of‐the‐art interrogation of cell surface proteins in the complex tissue setting.
Kati Fischermanns, Johannes Broichhagen
wiley   +1 more source

Nutrient/TOR signaling controls adipose mitochondrial transcription factor A (TFAM) to regulate organismal growth in Drosophila

FEBS Letters, EarlyView.
Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas, Shahoon Khan, Abhishek Sharma, Byoungchun Lee, Savraj S. Grewal   +4 more
wiley   +1 more source

Komparasi Paduan Ethanol dan Dietyl Ether (DEE) pada Gasoline Terhadap Performa Spark Ignition (SI) Engine

Infotekmesin: Media Komunikasi Ilmiah Politeknik Cilacap
The limited availability of fossil fuels and the growing demand for energy have led to a global energy crisis. Ethanol and DEE can be used as alternative energy to replace fossil fuels.
Firman Lukman Sanjaya, Faqih Fatkhurrozak, Nur Aidi Ariyanto, Sigit Setijo Budi, Andre Budhi Hendrawan, Syarifudin   +5 more
doaj   +1 more source

Epigenetic reprogramming of lineage switching in cancer

FEBS Letters, EarlyView.
Cancer cells rarely commit to a single identity. Epigenetic mechanisms and tumor microenvironment cues push epithelial cells toward flexible, hybrid states that can shift into mesenchymal, neuroendocrine, or stem‐like fates, driving metastasis, drug resistance, and tumor heterogeneity. Targeting the epigenetic regulators behind these transitions, using
Ezgi Boyvatlı, Burcu Akman, Ezgi Bağırsakçı, Nese Atabey, Serap Erkek‐Ozhan   +4 more
wiley   +1 more source

Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network

FEBS Letters, EarlyView.
Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley   +1 more source

The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers

Molecular Oncology, EarlyView.
The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce, Simone Bini, Marialuisa Sponziello, Giorgio Grani, Giulia Fiscon, Paola Paci, Lorenzo Farina, Rosa Falcone, Valentina Maggisano, Sebastiano Filetti, Cosimo Durante, Antonella Verrienti   +11 more
wiley   +1 more source

Effects of industrial hydrogen-rich gases on the performance of the spark ignition engine under various combustion modes

Case Studies in Thermal Engineering
Hydrogen is emerging as a promising alternative to traditional fossil fuels for the transportation. Additionally, the hydrogen-rich gases (HRG) can produce on a large scale during the process of chemical production.
Xiongbo Duan, Xianghe Chu, Mingchai Lai, Zhiqiang Sun   +3 more
doaj   +1 more source