Results 61 to 70 of about 11,815 (249)

Syndrome of inappropriate anti-diuretic hormone secretion in cancer patients: results of the first multicenter Italian study

open access: yesTherapeutic Advances in Medical Oncology, 2019
Background: Hyponatremia in cancer patients is often caused by the syndrome of inappropriate antidiuretic hormone secretion (SIADH). The aim of this observational multicenter study was to analyze the medical and economic implications of SIADH in this ...
Rossana Berardi   +37 more
doaj   +1 more source

An adolescent girl with syndrome of inappropriate antidiuretic hormone secretion preceding the diagnosis of olfactory neuroblastoma – a case report

open access: yesFrontiers in Endocrinology
ObjectivesWe present an adolescent in whom olfactory neuroblastoma (ONB) was detected on follow-up magnetic resonance imaging (MRI) 2.5 years after SIADH diagnosis.
Sabitha Sasidharan Pillai   +16 more
doaj   +1 more source

Idiopathic desquamative interstitial pneumonia in a child: a case report. [PDF]

open access: yes, 2014
Desquamative interstitial pneumonia is a rare form of interstitial lung disease in children. Respiratory symptoms appear progressively, are often subtle, and diagnosis is often delayed by a mean of 6 months after onset.
Aubert, J.D.   +4 more
core   +1 more source

The Evolving Landscape of Immunotoxicity: Charting Mechanisms and Future Strategies for Immune Checkpoint Inhibitor Adverse Events

open access: yesMed Research, Volume 1, Issue 3, Page 322-358, December 2025.
ABSTRACT The use of immune checkpoint inhibitors (ICIs) has significantly improved the efficacy of cancer therapy, but their associated immune‐related adverse events (irAEs) can severely compromise treatment safety. This review systematically summarizes the core mechanisms underlying irAEs, which include multi‐organ damage resulting from T‐cell ...
Anqi Lin   +8 more
wiley   +1 more source

Three Synchronous Tumors Discovered in SIADH Investigation [PDF]

open access: yes
Syndrome of Inappropriate Antidiuretic Hormone Secretion (SIADH) is a common cause of euvolemic hyponatremia which has many possible etiologies such as tumors (mainly lung cancers). We present a case of a 79-year old women hospitalized due to microcytic
Fonseca, Ricardo, Monteiro, Filipa
core   +1 more source

Central Osmolality Sensing for Arginine Vasopressin Release Is Mediated by WNK1‐OSR1/SPAK‐Kv3.1 Cascade

open access: yesThe FASEB Journal, Volume 39, Issue 22, 30 November 2025.
Extracellular hyperosmolality extracts water from the catalytic center of WNK1 increasing the kinase activity. WNK1 phosphorylates and activates OSR1/SPAK leading to increases in Kv3.1 activity. Enhanced Kv3.1 activity accelerates repolarization, increasing afterhyperpolarization (AHP) and/or shortening AP width to increase action potential firing ...
Xin Jin   +5 more
wiley   +1 more source

Hyponatraemia: etiology, management and outcome [PDF]

open access: yes, 2008
OBJECTIVE: To determine the etiology of hyponatraemia, the treatment instituted and the outcome of treatment in a tertiary care hospital setting. STUDY DESIGN: Case series.PLACE AND DURATION OF STUDY: The Aga Khan University Hospital, Karachi, between ...
Akhtar, Jaweed   +5 more
core   +1 more source

Neuroendocrine morbidity after pediatric optic gliomas: a longitudinal analysis of 166 children over 30 years [PDF]

open access: yes, 2015
Context: 50% of pediatric low-grade gliomas affect the optic pathway, hypothalamus and suprasellar areas (OP/HSGs) resulting in significant long-term neuroendocrinopathy.
Aquilina, K   +5 more
core   +1 more source

Guía de práctica clínica sobre el diagnóstico y tratamiento de la hiponatremia [PDF]

open access: yes, 2017
La hiponatremia se define como una concentración sérica de sodio
Allolio, Bruno   +19 more
core   +7 more sources

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