Results 161 to 170 of about 5,135,061 (391)

Development of an Artificial Intelligence Verification System Model for Clinical Biochemistry Laboratories Using Machine Learning

open access: yesiLABMED, EarlyView.
The constructed AI verification system performed excellently in terms of accuracy and efficiency. This study provides a new solution for the intelligent verification of clinical biochemistry laboratories and has certain application value. ABSTRACT Background With the exponential growth of testing samples in clinical biochemistry laboratories ...
Lin Zhu   +12 more
wiley   +1 more source

Protein glycosylation in lung cancer from a mass spectrometry perspective

open access: yesMass Spectrometry Reviews, EarlyView.
Abstract Lung cancer is a severe disease for which better diagnostic and therapeutic approaches are urgently needed. Increasing evidence implies that aberrant protein glycosylation plays a crucial role in the pathogenesis and progression of lung cancer.
Mirjam Balbisi   +2 more
wiley   +1 more source

Mass spectrometry imaging of N‐linked glycans: Fundamentals and recent advances

open access: yesMass Spectrometry Reviews, EarlyView.
Abstract With implications in several medical conditions, N‐linked glycosylation is one of the most important posttranslation modifications present in all living organisms. Due to their nontemplate synthesis, glycan structures are extraordinarily complex and require multiple analytical techniques for complete structural elucidation.
Tana V. Palomino, David C. Muddiman
wiley   +1 more source

Evaluation of L-fucose and Sialic Acid Levels in Patients With Colorectal Cancer and Control Subject

open access: yesResearch in Molecular Medicine, 2020
Background: Currently, glycans, which are known as functional molecules in the biological system, are being under study as potential cancer markers. This study aimed to determine the level of serum L-fucose and sialic acid as the biomarkers in patients ...
Roya Abbasinatajomrani   +3 more
doaj  

Mass Spectrometry Structural Proteomics Enabled by Limited Proteolysis and Cross‐Linking

open access: yesMass Spectrometry Reviews, EarlyView.
ABSTRACT The exploration of protein structure and function stands at the forefront of life science and represents an ever‐expanding focus in the development of proteomics. As mass spectrometry (MS) offers readout of protein conformational changes at both the protein and peptide levels, MS‐based structural proteomics is making significant strides in the
Haiyan Lu   +4 more
wiley   +1 more source

Increased Serum Sialic Acids in Depression.

open access: yesمجلة كلية الطب, 2007
Background: Total serum sialic acid (TSA) and lipid associated sialic acid (LSA) have not been measured yet in depressive disorders. Aim :The present study was undertaken to show if there is any change in the concentration of different forms of sialic ...
Hussein Kadhem Abdul Hussein   +2 more
doaj  

Quantifying Protein–Glycan Interactions Using Native Mass Spectrometry

open access: yesMass Spectrometry Reviews, EarlyView.
ABSTRACT Interactions between glycan‐binding proteins (GBPs) and carbohydrates (glycans) are essential to many biological processes relevant to human health and disease. For most GBPs, however, their glycan interactome—the repertoire of glycans recognized and their specificities—is poorly defined.
Duong T. Bui   +4 more
wiley   +1 more source

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