Results 191 to 200 of about 5,135,061 (391)

Structural Analysis of the SARS‐CoV‐2 Spike N‐Terminal Domain Across Wild‐Type and Recent Variants: A Comparative Study

open access: yesProteins: Structure, Function, and Bioinformatics, EarlyView.
ABSTRACT Since its first appearance in China, the molecular evolution of SARS‐CoV‐2 has progressed through altering the properties of the Spike protein, changing the virus ability to transmit and to evade host immune surveillance. Despite receiving less attention than the Receptor Binding Domain (RBD), the Spike N‐Terminal Domain (NTD) is crucial to ...
Miriana Quaranta   +2 more
wiley   +1 more source

The Sialic Acids

open access: hybrid, 1962
George W. Jourdian, Saul Roseman
openalex   +1 more source

From Membrane Composition to Antimicrobial Strategies: Experimental and Computational Approaches to AMP Design and Selectivity

open access: yesSmall, EarlyView.
Antimicrobial peptides (AMPs) are promising candidates for next‐generation antibiotics, acting through mechanisms such as membrane disruption and intracellular targeting. This review examines how variations in bacterial membrane composition critically influence AMP activity.
Paolo Rossetti   +5 more
wiley   +1 more source

Bioactive Polysulfate‐Based Nano‐Assemblies Against Virus Infection

open access: yesSmall, EarlyView.
Nano‐assemblies with a defined brush‐like corona are developed from sulfated polyglycerol to inhibit virus infection. The sulfate residues on the surface can actively bind the virus and entrap it from entering the host cells. This nanosystem is demonstrated potent inhibition against both HSV‐1 and SARs‐CoV‐2.
Guoxin Ma   +9 more
wiley   +1 more source

Biomaterial‐Based Emergency Intervention for Secondary Spinal Cord Injury

open access: yesSmall Science, EarlyView.
Emergency intervention using advanced biomaterials targets key pathological mechanisms to block secondary spinal cord injury (SCI) by inhibiting inflammation, reducing excitotoxicity, restoring the blood−spinal cord barrier, and limiting scar formation, which provides significant neural protection and promotes neural regeneration, offering promising ...
Jincheng Li   +5 more
wiley   +1 more source

Sialic Acid as an Index of the κ-Casein Content of Bovine Skimmilk

open access: bronze, 1963
J.R. Marier, H. Tessier, Dyson Rose
openalex   +1 more source

Tailored Metal‐Organic Framework‐Based Enzyme Hybrids: Immobilization Strategies, Improved Performance, and Biological Applications

open access: yesSmall Science, EarlyView.
Metal‐organic frameworks (MOFs) offer versatile platforms for enzyme immobilization to overcome their inherent fragility. However, challenges such as restricted conformation and mass transfer limitations remain. Advances in precise MOF design can help overcome these obstacles, expanding their applicability across diverse fields, highlighting the ...
Xiang Xu   +4 more
wiley   +1 more source

Home - About - Disclaimer - Privacy