Results 201 to 210 of about 5,135,061 (391)

Synthesis of Boronic Acid‐Functionalized Core–Shell Mesoporous Silica–TiO2 Nanocomposite for Specific Enrichment of Glycopeptides From Biological Samples

open access: yesSmall Methods, EarlyView.
The schematic illustrates a workflow showing the current investigation using a boronic acid‐functionalized core–shell mesoporous silica‐TiO₂ (CSMS@TiO₂‐GLYMO‐APB) for N‐glycopeptide enrichment from biological samples, involving trypsin digestion, enrichment, deglycosylation with PNGase F, and subsequent mass spectrometry (MALDI‐TOF MS and Nano‐LC‐MS/MS)
Mohamed Adly Gab‐Allah   +8 more
wiley   +1 more source

Investigating the Utility of Leukocyte Sialic Acid Measurements in Lysosomal Free Sialic Acid Storage Disorder. [PDF]

open access: yesJIMD Rep
Sabir MS   +9 more
europepmc   +1 more source

Diagnostics of Autoimmune Hepatitis Enabled by Non‐Invasive Clinical Proteomics

open access: yesAlimentary Pharmacology &Therapeutics, EarlyView.
Mass‐spectrometry‐based proteomic analyses of paired liver‐plasma samples from patients with AIH enabled discovery of numerous proteins showing high diagnostic accuracy. Proteomics may constitute a novel non‐invasive diagnostic tool for AIH if validated in larger, age‐ and sex‐matched cohorts.
Anne‐Sofie Houlberg Jensen   +20 more
wiley   +1 more source

The physiological and pathological effects of sphingolipid metabolism and signaling in the central nervous system

open access: yesBrain Pathology, EarlyView.
Sphingolipids are vital components of cell membranes. Metabolic disruptions of sphingolipids, including ceramide and sphingosine‐1‐phosphate, are linked to neurological disorders. This article summarizes the classification, structure, and metabolic processes of sphingolipids, and the physiological and pathological effects of sphingolipid metabolism and
Tian Li   +7 more
wiley   +1 more source

Mapping the sialic acid-binding sites of LuIII and H-1 parvovirus. [PDF]

open access: yesJ Virol
Busuttil K   +13 more
europepmc   +1 more source

Exploring Siglecs: Potential Modulators of Immune Cells in Food Allergy and Therapeutic Applications

open access: yesClinical &Experimental Allergy, EarlyView.
Sialic acid‐binding immunoglobulin‐type lectins (Siglecs) are inhibitory receptors present on all immune cells involved in the allergic reaction. Currently, research is mostly focussed on targeting Siglecs on mast cells to possibly treat food allergies.
J. S. H. Schaapherder   +5 more
wiley   +1 more source

Sialic Acid-Containing Glycolipids Extend the Receptor Repertoire of Enterovirus-D68. [PDF]

open access: yesACS Infect Dis
Pereirinha da Silva AK   +9 more
europepmc   +1 more source

Macrophage Efferocytosis as a Therapeutic Strategy in Intervertebral Disc Degeneration

open access: yesCell Proliferation, EarlyView.
Macrophages, integral to degenerated intervertebral discs, play a critical role in disc degeneration. By performing efferocytosis, they clear apoptotic cells. This article explores the process of efferocytosis, its molecular mechanisms, potential therapeutic implications for intervertebral disc degeneration and future strategies for targeted treatments.
Shijie Chen   +9 more
wiley   +1 more source

Home - About - Disclaimer - Privacy